Colona 30 Tablets

Colona 30 Tablets

Description:

Colona 30 Tablets is a prescription-only antispasmodic and gastrointestinal medication used for the management of irritable bowel syndrome (IBS) and functional gastrointestinal disorders. It combines mebeverine, a direct-acting smooth muscle relaxant of the gut, with sulpiride, a dopamine antagonist that helps modulate gut–brain interaction and relieve associated psychosomatic and mood-related symptoms. Colona helps reduce abdominal pain, cramps, bloating, gas, and bowel habit disturbances, improving overall digestive comfort and quality of life. It is intended for adult use under medical supervision.

Indications:

• Management of irritable bowel syndrome (IBS).
• Relief of abdominal cramps and painful contractions of the small and large intestine.
• Management of changes in bowel habits such as constipation, diarrhea, or alternating patterns associated with IBS.
• Reduction of bloating, gas, and abdominal discomfort due to functional bowel disorders.
• Functional gastrointestinal disorders with a psychosomatic or anxiety-related component.
• Adjunctive treatment in patients with digestive symptoms associated with mild mental or mood disturbances, as assessed by a physician.

Active Ingredients / Key Components:

• Mebeverine hydrochloride – concentration per tablet not clearly specified in available references (commonly 135 mg, but exact strength for this specific pack is not confirmed).
• Sulpiride – concentration per tablet not clearly specified in available references (commonly low-dose, but exact strength for this specific pack is not confirmed).
• Other excipients: Full list of inactive ingredients (e.g., fillers, binders, coating agents) is not available in the provided information. Please refer to the product leaflet for complete excipient details.

Dosage & Administration / How to Use:

• Use only as prescribed by your physician. Do not self-medicate.
• Typical adult dosing for IBS and functional bowel disorders is usually 1 tablet taken 2–3 times daily, but the exact dose, frequency, and duration must be determined by the treating doctor based on the patient’s condition and response.
• Tablets should be swallowed whole with a sufficient amount of water. Do not crush, chew, or break the tablets unless your doctor or pharmacist specifically instructs otherwise.
• Colona may be taken before meals to help prevent post-meal abdominal cramps, unless otherwise directed by your doctor.
• Do not exceed the prescribed dose or extend the duration of treatment without medical advice.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• In elderly patients or those with other medical conditions, dosing adjustments may be required at the discretion of the physician.

Clinical Benefits:

• Helps relax intestinal smooth muscles, reducing spasms and painful contractions in the small and large intestine.
• Alleviates key IBS symptoms such as abdominal pain, cramps, bloating, and gas.
• Contributes to normalization of bowel habits, helping reduce episodes of constipation, diarrhea, or alternating patterns associated with functional bowel disorders.
• Supports management of psychosomatic digestive complaints by modulating dopamine activity in the brain–gut axis, which may help improve associated mood or anxiety-related symptoms under medical supervision.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to mebeverine, sulpiride, or any of the excipients in the formulation.
• Contraindicated in patients with prolactin-dependent tumors (e.g., prolactinomas, breast cancer) due to the dopamine antagonist effect of sulpiride.
• Use with extreme caution in patients with a history of epilepsy, seizures, or conditions that lower seizure threshold.
• Use with caution in patients with severe renal impairment or hepatic impairment; dose adjustment or alternative therapy may be required.
• Sulpiride may cause drowsiness or dizziness; avoid driving, operating machinery, or performing tasks requiring alertness until you know how the medicine affects you.
• May increase prolactin levels; consult your doctor if you experience breast tenderness, galactorrhea, menstrual disturbances, or sexual dysfunction.
• Inform your doctor about all other medications you are taking, especially antipsychotics, antidepressants, antiarrhythmics, levodopa, and medications that affect heart rhythm or central nervous system.
• Consult your doctor before use if pregnant or planning pregnancy. Use during pregnancy should only occur if clearly needed and prescribed by a physician.
• Breastfeeding: Sulpiride may pass into breast milk; breastfeeding is generally not recommended during treatment unless specifically advised by your doctor.
• Patients with a history of mood disorders, depression, or other psychiatric conditions should be closely monitored by their physician while using this product.
• Not intended for use in children unless specifically prescribed by a pediatric specialist.
• Consult your doctor before use if you have heart disease, arrhythmias, a family history of QT prolongation, electrolyte disturbances, or if you are taking other medicines that may prolong QT interval.
• Consult your doctor before use if you have diabetes, kidney disease, liver disease, or any chronic medical condition.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include mild gastrointestinal disturbances such as nausea, stomach discomfort, or constipation.
• Sulpiride-related side effects can include drowsiness, dizziness, restlessness, weight changes, or increased prolactin levels leading to breast tenderness, galactorrhea, or menstrual irregularities.
• Less common but serious side effects may include extrapyramidal symptoms (muscle stiffness, tremor, involuntary movements), severe allergic reactions (rash, itching, swelling, difficulty breathing), or significant mood or behavioral changes.
• Very rare but serious cardiac side effects such as QT prolongation or arrhythmias may occur, especially in predisposed patients or when combined with other QT-prolonging drugs.
• If you experience severe abdominal pain, persistent vomiting, high fever, severe dizziness, fainting, palpitations, difficulty breathing, or any other worrying symptoms, stop taking the medicine and seek immediate medical attention.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature specified on the package insert (exact temperature range not available in the provided information; refer to the official leaflet).

Specifications:

• Product form: film-coated tablets.
• Pack size: 30 tablets per pack.
• Intended use: prescription antispasmodic and gastrointestinal medicine for adults, used under medical supervision.
• Route of administration: oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.