Co Aprovel 150 Mg 14 Tablets

Co Aprovel 150 Mg 14 Tablets

Description:

Co Aprovel 150 mg 14 tablets (Coaprovel 150/12.5 mg) is a prescription antihypertensive medicine that combines two active ingredients: irbesartan (an angiotensin II receptor blocker – ARB) and hydrochlorothiazide (a thiazide diuretic). It is used to lower high blood pressure (hypertension) in adults, especially when blood pressure is not adequately controlled with irbesartan alone. By relaxing blood vessels and increasing the excretion of excess salt and water, Co Aprovel helps reduce cardiovascular risk, protect the heart, kidneys, and blood vessels, and support long‑term blood pressure control.

Indications:

• Treatment of essential hypertension (high blood pressure) in adults.
• Management of patients whose blood pressure is not adequately controlled by irbesartan alone.
• Helps reduce the risk of complications related to uncontrolled hypertension such as stroke, heart attack, and kidney damage (as part of a comprehensive cardiovascular risk management plan prescribed by a doctor).
• May be used in patients who require both an angiotensin II receptor blocker and a diuretic to achieve target blood pressure levels, as directed by a physician.

Active Ingredients / Key Components:

• Irbesartan – 150 mg per tablet (angiotensin II receptor blocker – ARB).
• Hydrochlorothiazide – 12.5 mg per tablet (thiazide diuretic).
• Excipients: Full list of inactive ingredients (such as tablet fillers, binders, colorants, and coating agents) is not available in the provided information. Please refer to the official package leaflet for complete excipient details.

Dosage & Administration / How to Use:

• Co Aprovel 150/12.5 mg is for oral use only and should be taken exactly as prescribed by your doctor.
• Typical adult dose: One tablet once daily. Your doctor may adjust the dose based on your blood pressure response and clinical condition. Do not change your dose without medical advice.
• Can be taken with or without food. Swallow the tablet whole with a glass of water; do not crush or chew unless advised by your pharmacist or doctor.
• Try to take the tablet at the same time each day to maintain consistent blood levels and improve adherence.
• If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed tablet.
• Do not stop taking Co Aprovel suddenly without consulting your doctor, as this may cause your blood pressure to rise again.
• Regular monitoring of blood pressure, kidney function, and electrolytes (especially potassium, sodium, and magnesium) is recommended during treatment.

Clinical Benefits:

• Effectively lowers high blood pressure by combining two complementary mechanisms: vasodilation (irbesartan) and diuresis (hydrochlorothiazide).
• Helps reduce the risk of serious cardiovascular events associated with uncontrolled hypertension, such as stroke and heart attack, when used as part of a comprehensive treatment plan.
• Supports kidney protection in hypertensive patients by reducing intraglomerular pressure and overall blood pressure load (especially beneficial in patients with additional risk factors, as evaluated by the physician).
• Once‑daily dosing improves treatment adherence and provides sustained 24‑hour blood pressure control for many patients.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to irbesartan, hydrochlorothiazide, other sulfonamide‑derived drugs, or any component of the tablet.
• Contraindicated during the second and third trimesters of pregnancy. Use of ARBs is not recommended in the first trimester. If pregnancy is planned or suspected, inform your doctor immediately to switch to a safer alternative.
• Contraindicated in severe kidney impairment, anuria (inability to produce urine), or severe liver impairment, unless specifically evaluated and approved by a specialist.
• Contraindicated in patients with refractory hypokalemia, hypercalcemia, or severe hyponatremia.
• Use with caution in patients with kidney disease, liver disease, heart failure, coronary artery disease, diabetes, gout, or a history of electrolyte imbalance.
• May cause electrolyte disturbances (low potassium, low sodium, low magnesium, or high uric acid). Regular blood tests are recommended.
• May increase sensitivity to sunlight (photosensitivity) due to hydrochlorothiazide; avoid excessive sun exposure and use sun protection.
• Can interact with other medicines such as lithium, other antihypertensives, potassium‑sparing diuretics, potassium supplements, NSAIDs, and certain antidiabetic drugs. Inform your doctor about all medications and supplements you are taking.
• Not recommended for use in children and adolescents, as safety and efficacy have not been well established in this age group.
• Consult your doctor before use if pregnant, nursing, taking medications, or have medical conditions such as kidney disease, liver disease, diabetes, heart failure, or gout.
• Keep out of reach of children.
• This product is a prescription antihypertensive medicine and should only be used under medical supervision.

Side Effects:

• Common side effects may include dizziness, headache, fatigue, weakness, nausea, abdominal discomfort, or increased urination, especially at the beginning of treatment.
• Electrolyte disturbances such as low potassium (hypokalemia), low sodium (hyponatremia), or increased uric acid (which may trigger gout) can occur due to the diuretic component.
• Less common side effects may include muscle cramps, palpitations, dry mouth, changes in kidney function tests, or mild increases in blood sugar or cholesterol.
• Serious but rare side effects include severe allergic reactions (rash, itching, swelling of face/lips/tongue, difficulty breathing), severe dizziness or fainting, significant decrease in urine output, severe electrolyte imbalance, or jaundice. Seek immediate medical attention if these occur.
• If you experience persistent or bothersome side effects, contact your doctor or pharmacist for advice.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer carton to protect from light. Do not store above the temperature specified on the package (usually below 25°c, if indicated). Keep container tightly closed and keep out of reach of children. Do not use after the expiry date printed on the pack.

Specifications:

• Form: Tablets for oral use.
• Strength per tablet: Irbesartan 150 mg + hydrochlorothiazide 12.5 mg.
• Pack size: 14 tablets (sufficient for 14 days of once‑daily therapy, unless otherwise directed by your physician).
• Product type: Prescription antihypertensive combination medicine.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.