Coveram 10/10 Mg 15 Tablets

Coveram 10/10 Mg 15 Tablets

Description:

Coveram 10/10 mg is a prescription combination antihypertensive medicine containing perindopril (an angiotensin-converting enzyme inhibitor) and amlodipine (a calcium channel blocker). It is used for the long-term management of high blood pressure and certain heart and vascular conditions in adults, helping to reduce cardiovascular risk such as heart attack and stroke. By combining two complementary mechanisms of action in one tablet, Coveram 10/10 mg improves blood pressure control, supports heart function, and enhances adherence to therapy.

Indications:

• Treatment of mild to moderate essential hypertension (high blood pressure) in adults, particularly when blood pressure is not adequately controlled by either perindopril or amlodipine alone.
• Management of stable coronary artery disease in adults to reduce the risk of cardiovascular events such as myocardial infarction (heart attack) and stroke.
• Reduction of cardiovascular risk in hypertensive patients with a history of myocardial infarction and/or established stable coronary disease.
• May be used in patients requiring both an ACE inhibitor and a calcium channel blocker for optimal blood pressure and vascular protection, as directed by a physician.

Active Ingredients / Key Components:

• Perindopril arginine – 10 mg per tablet (ace inhibitor). Exact salt form and equivalence may vary by market; 10 mg is the labeled strength.
• Amlodipine – 10 mg per tablet (dihydropyridine calcium channel blocker).
• Excipients: Information on inactive ingredients (such as lactose, cellulose, or others) is not provided in the available data. Full excipient list and concentrations are unavailable here; please refer to the official package leaflet.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician experienced in the management of hypertension and cardiovascular disease.
• Typical adult dose: 1 tablet of Coveram 10/10 mg once daily, preferably taken in the morning at the same time each day. The exact dose and strength are individualized by the doctor.
• Route of administration: Oral. Swallow the tablet whole with a glass of water; do not crush or chew.
• With or without food: Can generally be taken with or without food; however, take it consistently in the same way each day as advised by your doctor.
• Duration of use: Long-term treatment. Do not stop taking Coveram without consulting your doctor, even if you feel well, as high blood pressure often has no symptoms.
• Missed dose: If you forget a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed tablet.
• Special populations: Dose adjustment may be required in elderly patients, those with kidney or liver impairment, or patients on other antihypertensive drugs. Follow physician instructions strictly.

Clinical Benefits:

• Provides dual antihypertensive action by combining an ace inhibitor (perindopril) and a calcium channel blocker (amlodipine) for more effective blood pressure control.
• Helps reduce the risk of major cardiovascular events such as heart attack and stroke in patients with hypertension and/or stable coronary artery disease.
• Improves blood flow by relaxing peripheral and coronary blood vessels, decreasing peripheral vascular resistance and myocardial oxygen demand.
• Supports long-term heart and vascular health in patients with a history of myocardial infarction or established coronary disease when used as part of a comprehensive treatment plan.
• Convenient once-daily single-tablet regimen that may enhance treatment adherence compared with taking perindopril and amlodipine separately.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to perindopril, other ace inhibitors, amlodipine, other dihydropyridine calcium channel blockers, or any component of the formulation.
• Contraindicated in patients with a history of angioedema (swelling of the face, lips, tongue, or throat) associated with previous ace inhibitor therapy or hereditary/idiopathic angioedema.
• Contraindicated during the second and third trimesters of pregnancy; ace inhibitors can cause serious harm or death to the developing fetus. Use in the first trimester is not recommended.
• Contraindicated in severe hypotension, cardiogenic shock, or in patients with hemodynamically unstable heart failure after acute myocardial infarction (amlodipine-related).
• Use with caution in patients with renal impairment, renal artery stenosis, liver impairment, heart failure, aortic stenosis, hypertrophic cardiomyopathy, or those on diuretics or other blood pressure–lowering drugs.
• Monitor kidney function and serum potassium periodically, especially in patients with renal impairment, diabetes, or those taking potassium-sparing diuretics, potassium supplements, or other medications that increase potassium.
• May cause symptomatic hypotension, particularly in volume-depleted patients (e.g., on high-dose diuretics, low-salt diet, vomiting, or diarrhea). Start and adjust dose under medical supervision.
• Use with caution in patients with diabetes; ace inhibitors may affect blood glucose control and require monitoring.
• Alcohol may enhance the blood pressure–lowering effect and increase the risk of dizziness or fainting.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding, or if you have kidney disease, liver disease, heart failure, coronary artery disease, diabetes, or are taking other antihypertensive or cardiovascular medications.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision; it is a prescription-only medicine that must be used under a doctor’s care.
• Keep out of reach of children.
• Do not share this medication with others, even if they have similar symptoms or conditions.

Side Effects:

• Common side effects may include headache, dizziness, flushing, fatigue, ankle or leg swelling (peripheral edema), palpitations, cough (typically dry, related to ace inhibitor), nausea, abdominal discomfort, or gastrointestinal upset.
• Less common side effects can include muscle cramps, rash, pruritus (itching), changes in taste, low blood pressure (hypotension), or sleep disturbances.
• Serious but rare side effects: angioedema (swelling of face, lips, tongue, or throat), severe hypotension, chest pain or worsening angina, irregular heartbeat, severe dizziness or fainting, jaundice or signs of liver problems, or significant decrease in urine output or kidney function.
• Stop the medication and seek immediate medical attention if you experience signs of angioedema, severe allergic reaction, chest pain, difficulty breathing, or severe dizziness/fainting.
• This is not a complete list of side effects. For full safety information, consult your doctor or pharmacist and read the official patient information leaflet.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the packaging. Store at or below the temperature specified on the pack (exact temperature range not provided here; refer to the product carton or leaflet).

Specifications:

• Product type: Prescription antihypertensive medicine (ace inhibitor + calcium channel blocker combination).
• Strength: 10 mg perindopril + 10 mg amlodipine per tablet.
• Form: Film-coated tablets.
• Pack size: 15 tablets per pack.
• Intended users: Adult patients as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.