Coversyl Plus 5/1.25 Mg 15 Tablets

Coversyl Plus 5/1.25 Mg 15 Tablets

Description:

Coversyl Plus 5/1.25 mg is a prescription antihypertensive medicine combining perindopril (an ace inhibitor) and indapamide (a thiazide-like diuretic) in tablet form. It is used for long-term management of high blood pressure (hypertension) in adults, especially when a combination of an ace inhibitor and a diuretic is clinically indicated. By relaxing blood vessels and promoting mild fluid and salt loss, Coversyl Plus helps reduce blood pressure, lower cardiovascular risk, and protect heart and blood vessel health. This product is intended for use under medical supervision only.

Indications:

• Treatment of essential (primary) hypertension in adults.
• Management of high blood pressure in patients who require combination therapy with an ace inhibitor and a diuretic.
• Reduction of cardiovascular risk associated with uncontrolled hypertension, such as risk of stroke, heart attack, and other vascular complications (as part of a comprehensive treatment plan prescribed by a physician).
• Control of blood pressure in patients who have not achieved adequate response with perindopril or indapamide alone (as decided by the treating doctor).

Active Ingredients / Key Components:

• Perindopril arginine – 5 mg per tablet (ace inhibitor; prodrug converted to active perindoprilat).
• Indapamide – 1.25 mg per tablet (thiazide-like diuretic).
• Other excipients: Exact list of inactive ingredients (such as fillers, binders, coating agents, preservatives, and coloring agents) is not available in the provided information. Please refer to the official package leaflet for the full excipient list.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician. Do not self-medicate or adjust the dose without medical advice.
• Typical adult dose: 1 tablet once daily. The exact dose, timing, and duration are determined by your doctor based on your blood pressure, kidney function, and overall health.
• Administration: Swallow the tablet whole with a glass of water. Do not crush or chew.
• Timing: Often taken in the morning, preferably at the same time each day. It may be taken with or without food, as directed by your doctor.
• If you miss a dose: Take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed tablet.
• Do not stop taking Coversyl Plus suddenly without consulting your doctor, even if you feel well, as hypertension often has no symptoms.
• Your doctor may regularly monitor blood pressure, kidney function, and blood electrolytes (especially potassium and sodium) during treatment.

Clinical Benefits:

• Provides effective blood pressure control by combining two complementary mechanisms: vasodilation (perindopril) and mild diuresis (indapamide).
• Helps reduce both systolic and diastolic blood pressure, supporting long-term cardiovascular protection.
• Improves arterial compliance and reduces total peripheral resistance, enhancing overall vascular health.
• Decreases sodium and water retention, which can help reduce blood volume and blood pressure.
• Supports heart function and may contribute to lowering the risk of complications such as stroke, heart attack, and heart failure when used as part of a comprehensive treatment plan.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to perindopril, other ace inhibitors, indapamide, sulfonamides, or any component of the formulation.
• Contraindicated in patients with a history of angioedema (hereditary, idiopathic, or ace inhibitor–induced).
• Contraindicated in severe renal impairment, severe hepatic impairment, and in patients with anuria or severe electrolyte disturbances (such as severe hypokalemia).
• Do not use during the second and third trimesters of pregnancy; ace inhibitors can cause serious fetal harm. Use in the first trimester is also not recommended.
• Not recommended during breastfeeding unless clearly needed and under strict medical supervision.
• Use with caution in patients with renal artery stenosis, dehydration, heart failure, liver disease, diabetes, or those on a low-salt diet.
• Concomitant use with potassium-sparing diuretics, potassium supplements, or salt substitutes containing potassium may increase the risk of hyperkalemia; requires close monitoring.
• May cause dizziness or fatigue, especially at the start of treatment or when the dose is changed. Avoid driving or operating machinery until you know how the medicine affects you.
• Alcohol may enhance the blood pressure–lowering effect and increase the risk of dizziness or fainting.
• Consult your doctor before use if pregnant, nursing, taking other medications (especially diuretics, other antihypertensives, lithium, nsaids, or potassium-altering drugs), or if you have kidney disease, liver disease, heart failure, diabetes, or electrolyte imbalances.
• Not intended to diagnose, treat, cure, or prevent any disease without a doctor’s prescription and supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects: dizziness, headache, fatigue, low blood pressure (hypotension), cough (dry, persistent), gastrointestinal discomfort (nausea, abdominal pain, constipation, or diarrhea).
• Possible effects related to diuretic component: increased urination, changes in blood electrolytes (low potassium, low sodium), muscle cramps, or weakness.
• Less common but serious side effects: angioedema (swelling of face, lips, tongue, or throat), severe dizziness or fainting, irregular heartbeat, severe abdominal pain, jaundice (yellowing of skin or eyes), or signs of severe dehydration.
• Stop the medicine and seek immediate medical attention if you experience difficulty breathing, swelling of the face or throat, severe dizziness, chest pain, or signs of an allergic reaction.
• This is not a complete list of side effects. Always consult your doctor or pharmacist if you notice any unusual symptoms.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Do not store above the temperature recommended in the official leaflet (exact temperature range is not available in the provided information; refer to the package insert).

Specifications:

• Product type: Prescription antihypertensive medicine (ace inhibitor + thiazide-like diuretic combination).
• Strength: Perindopril arginine 5 mg + indapamide 1.25 mg per tablet.
• Form: Film-coated tablets.
• Pack size: 15 tablets per pack.
• Intended use: Adult patients as prescribed by a healthcare professional for the management of high blood pressure.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.