Macrofuran 100 Mg 30 Capsules

Macrofuran 100 Mg 30 Capsules

Description:

Macrofuran 100 mg 30 capsules is a prescription oral antibiotic medicine containing nitrofurantoin, a nitrofuran derivative used primarily as a urinary germicide. It is indicated for the treatment and prevention of susceptible bacterial urinary tract infections (UTIs), especially infections of the lower urinary tract such as cystitis. Macrofuran works by inhibiting bacterial DNA, RNA, and cell wall synthesis, leading to the suppression and elimination of sensitive bacteria in the urinary tract. It is suitable for adults and, when prescribed, for certain pediatric patients, under direct medical supervision.

Indications:

• Treatment of acute uncomplicated urinary tract infections (UTIs) caused by susceptible organisms.
• Management of lower urinary tract infections such as acute cystitis and recurrent cystitis, as prescribed by a physician.
• Prevention of recurrent urinary tract infections in selected patients when recommended by a healthcare professional.
• Relief of UTI-related symptoms such as burning during urination, frequent urination, urgency, and lower abdominal discomfort, as the infection is treated.

Active Ingredients / Key Components:

• Nitrofurantoin – 100 mg per capsule.
• Other inactive ingredients (excipients) are not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).

Dosage & Administration / How to Use:

• Use only as prescribed by a physician. Do not self-medicate with antibiotics.
• Typical adult dose for uncomplicated urinary tract infection (for reference only; your doctor may adjust): nitrofurantoin 100 mg taken orally twice daily with food, for the duration specified by the doctor (commonly 5–7 days). Exact regimen must be determined by the prescriber.
• Always take capsules with food or milk to improve absorption and reduce gastrointestinal side effects.
• Swallow the capsule whole with a glass of water. Do not crush or chew unless your doctor or pharmacist specifically advises otherwise.
• Take doses at evenly spaced intervals to maintain effective antibiotic levels in the urine.
• Complete the full course of therapy even if symptoms improve earlier, to prevent recurrence and antibiotic resistance.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Use in children, elderly patients, and those with kidney or liver problems must be strictly under medical supervision with adjusted dosing as required.

Clinical Benefits:

• Effectively targets and eliminates susceptible bacteria causing urinary tract infections.
• Concentrates in the urine, providing strong local antibacterial action in the urinary tract.
• Helps relieve UTI symptoms such as burning, frequency, and urgency as the infection resolves.
• May be used in selected patients to help prevent recurrent UTIs when prescribed for prophylaxis.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to nitrofurantoin or any component of the formulation.
• Contraindicated in patients with significantly impaired renal function (severe kidney disease) due to reduced drug clearance and increased risk of toxicity.
• Use with caution in patients with liver disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency, anemia, diabetes, electrolyte imbalance, or vitamin B deficiency, and in elderly patients.
• May cause pulmonary (lung) reactions, including acute or chronic pulmonary fibrosis; discontinue immediately and seek medical help if you develop cough, chest pain, shortness of breath, or fever.
• May cause hepatic (liver) toxicity; seek medical advice if you notice jaundice (yellowing of skin/eyes), dark urine, severe fatigue, or abdominal pain.
• Drug interactions: anticholinergic drugs may increase nitrofurantoin bioavailability by delaying gastric emptying; probenecid may decrease renal clearance and increase serum levels, raising toxicity risk; magnesium trisilicate may delay or decrease absorption; food increases nitrofurantoin bioavailability.
• May interfere with certain laboratory tests, including serum glucose (decrease), elevated serum bilirubin and alkaline phosphatase, elevated urinary creatinine, and false-positive urinary glucose with Benedict’s reagent.
• Consult your doctor before use if you are pregnant or breastfeeding. Nitrofurantoin is generally avoided at term (late pregnancy) and in neonates due to risk of hemolytic anemia.
• Not suitable for infants below 1 month of age unless specifically directed by a specialist.
• Do not use for viral infections (such as cold or flu) or for infections outside the urinary tract.
• Do not share this medicine with others, even if they have similar symptoms.
• Consult your doctor before use if pregnant, nursing, taking other medications, or if you have kidney disease, liver disease, anemia, lung disease, diabetes, or G6PD deficiency.
• Keep out of reach of children.

Side Effects:

• Common side effects: nausea, vomiting, loss of appetite, abdominal discomfort, diarrhea, headache, and dizziness. Taking the medicine with food may reduce stomach upset.
• Less common side effects: rash, itching, fever, chills, drowsiness, or mild shortness of breath.
• Serious side effects (seek immediate medical attention): severe allergic reactions (swelling of face, lips, tongue, or throat; difficulty breathing), severe skin reactions, persistent cough, chest pain, marked shortness of breath, jaundice, dark urine, severe fatigue, numbness or tingling in hands or feet (possible peripheral neuropathy), or unusual bruising/bleeding.
• If you experience persistent or worsening side effects, stop the medication and contact your doctor promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the container tightly closed and store at or below the temperature recommended on the package (specific temperature not provided in available information). Do not use after the expiry date printed on the pack. Keep out of reach of children.

Specifications:

• Product type: Oral antibiotic medicine (systemic urinary tract antibiotic).
• Active ingredient strength: nitrofurantoin 100 mg per capsule.
• Form: Hard capsules for oral use.
• Pack size: 30 capsules per pack.
• Intended users: Adults and selected pediatric patients as prescribed by a physician.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.