Doliprane 1000 Mg 20 Tab

Doliprane 1000 Mg 20 Tab

Description:

Doliprane 1000 mg is a branded paracetamol (acetaminophen) medicine from Sanofi, formulated as oral tablets for effective relief of pain and reduction of fever. Each tablet contains 1000 mg of paracetamol, a well-established non‑narcotic analgesic and antipyretic that acts primarily in the central nervous system to raise the pain threshold and normalize elevated body temperature. It is commonly used for headache, migraine, toothache, musculoskeletal pain, menstrual pain, and fever associated with colds, flu, and other infections. Doliprane 1000 mg is intended for adult use and should be taken exactly as directed to avoid overdose and liver toxicity.

Indications:

• Relief of mild to moderate pain such as headache, migraine, toothache, back pain, muscle pain, and joint pain.
• Reduction of fever associated with common cold, influenza, and other infectious conditions.
• Symptomatic relief of pain and fever in acute conditions such as sore throat, post‑vaccination reactions, and minor injuries.
• Adjunctive treatment for pain in acute gout attacks (as an analgesic and antipyretic, not disease‑modifying).
• Suitable when non‑steroidal anti‑inflammatory drugs (NSAIDs) are not tolerated or contraindicated (e.g., gastric sensitivity, certain cardiovascular or renal conditions), as advised by a physician.

Active Ingredients / Key Components:

• Paracetamol (Acetaminophen) – 1000 mg per tablet.
• Excipients: Other inactive ingredients (tablet bases, binders, coatings, etc.) are present but specific excipient names and concentrations , please check the product leaflet or the manufacturer’s official website.

Dosage & Administration / How to Use:

• Route of administration: Oral use only.
• Adults and adolescents (usually ≥ 15 years, depending on body weight): 1 tablet (1000 mg) per dose, taken with a full glass of water.
• Dosing interval: Leave at least 4–6 hours between doses.
• Maximum daily dose: Do not exceed 3000–4000 mg paracetamol per day (i.e., 3–4 tablets of 1000 mg) including all other paracetamol‑containing products. In patients with liver impairment or as advised by a doctor, lower maximum daily doses may be required.
• Food: Can be taken with or without food. Taking with food may reduce gastric discomfort in sensitive individuals.
• Duration of use without medical advice: Do not use for more than 3 days for fever or 5 days for pain without consulting a healthcare professional.
• Special populations: Use with caution and under medical supervision in patients with hepatic or renal impairment, chronic alcoholism, or low body weight. Not recommended for children due to the high 1000 mg strength; pediatric formulations with appropriate doses should be used instead.
• Missed dose: If a dose is missed, take it when remembered, but never double the dose or take two doses close together to make up for a missed dose.

Clinical Benefits:

• Provides effective analgesia by raising the pain threshold through central inhibition of cyclo‑oxygenase in the brain.
• Reduces fever by acting on the hypothalamic thermoregulatory center and blocking the effects of endogenous pyrogens.
• Non‑narcotic profile, so it does not cause opioid‑type dependence or respiratory depression at recommended doses.
• Generally well tolerated when used at recommended doses, making it suitable for patients who cannot take NSAIDs due to gastric, renal, or cardiovascular concerns (under medical guidance).

Warnings & Contraindications:

• Do not exceed the recommended dose. Overdose of paracetamol can cause serious, potentially fatal liver damage.
• Contraindications: Known hypersensitivity or allergy to paracetamol or any component of the formulation; severe hepatic impairment or active severe liver disease, unless specifically directed by a physician.
• Avoid concomitant use with other medicines containing paracetamol (acetaminophen) to prevent unintentional overdose.
• Use with extreme caution in patients with liver disease, chronic alcoholism, malnutrition, or dehydration, as the risk of hepatotoxicity is increased.
• Use with caution in renal impairment; dose adjustment or extended dosing interval may be necessary as advised by a doctor.
• Drug interactions: Cholestyramine may reduce absorption of paracetamol if taken close in time. Activated charcoal given immediately after ingestion reduces paracetamol absorption. Domperidone and metoclopramide can enhance absorption and speed of onset. Chronic excessive alcohol intake potentiates paracetamol‑induced liver toxicity.
• Consult your doctor before use if you are pregnant or breastfeeding. Paracetamol is generally considered compatible when used at recommended doses, but medical advice is recommended.
• Consult your doctor before use if you are taking other medications, especially anticoagulants (e.g., warfarin), enzyme‑inducing drugs, or have conditions such as liver disease, kidney disease, chronic alcohol use, or malnutrition.
• Discontinue use and seek medical advice if pain or fever persists, worsens, or is accompanied by other worrying symptoms (e.g., rash, persistent headache, stiff neck, shortness of breath).
• Not intended to diagnose, treat, cure, or prevent any disease beyond its approved indications as an analgesic and antipyretic.
• Keep out of reach of children.

Side Effects:

• Common (usually mild): Nausea, vomiting, mild gastrointestinal discomfort, or abdominal pain may occur in some individuals.
• Allergic reactions: Skin rash, itching, urticaria, facial or tongue swelling, and difficulty breathing may indicate hypersensitivity. Stop the medicine and seek immediate medical attention if these occur.
• Hepatic effects: High doses or prolonged use, especially in patients with liver disease or chronic alcohol use, can cause serious liver damage. Symptoms of overdose or liver injury may include nausea, vomiting, loss of appetite, sweating, abdominal pain, and jaundice (yellowing of skin or eyes). Immediate medical attention is required if overdose is suspected.
• Hematologic effects (rare): Thrombocytopenia, leukopenia, or other blood disorders have been reported rarely; seek medical advice if you notice unusual bleeding, bruising, or persistent infections.
• In case of any unexpected or severe side effects, stop taking Doliprane 1000 mg and consult a healthcare professional promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer packaging to protect from light. Do not store above the temperature indicated on the pack (specific temperature not available in the provided information). Keep container tightly closed and keep out of reach of children.

Specifications:

• Form: Tablets for oral use.
• Strength: 1000 mg paracetamol per tablet.
• Pack size: 20 tablets per pack.
• Product type: Analgesic and antipyretic medicine.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.