GEOCAND PLUS 16.0MG 21 TAB

GEOCAND PLUS 16.0MG 21 TAB

Description:

GEOCAND PLUS 16/12.5 mg 21 tab is a prescription antihypertensive medicine that combines candesartan cilexetil (an angiotensin II receptor blocker) with hydrochlorothiazide (a thiazide diuretic). It is used to lower high blood pressure in adults when monotherapy is insufficient, helping to reduce the risk of cardiovascular complications such as stroke and heart attack. This fixed-dose combination from Geopharma provides dual blood pressure control by relaxing blood vessels and promoting gentle removal of excess salt and water.

Indications:

• Treatment of essential hypertension (high blood pressure) in adults.
• Patients whose blood pressure is not adequately controlled with candesartan cilexetil alone.
• Patients already stabilized on candesartan cilexetil and hydrochlorothiazide given separately, who may benefit from a fixed-dose combination.
• Helps reduce the risk of cardiovascular events associated with long-term uncontrolled hypertension, such as stroke, myocardial infarction, and heart failure (as part of a comprehensive treatment plan).

Active Ingredients / Key Components:

• Candesartan cilexetil – 16 mg per tablet (angiotensin II receptor blocker / ARB).
• Hydrochlorothiazide – 12.5 mg per tablet (thiazide diuretic).
• Other excipients: Information on inactive ingredients is not available in the provided data. Refer to the package insert for full excipient list.

Dosage & Administration / How to Use:

• Usual adult dose: One tablet of GEOCAND PLUS 16/12.5 mg once daily, or as directed by the prescribing physician.
• Swallow the tablet whole with a glass of water; do not crush or chew.
• Can be taken with or without food, preferably at the same time each day to maintain consistent blood levels.
• Dosage may be adjusted by the physician based on blood pressure response and clinical status. Do not change your dose or stop the medication without medical advice.
• If a dose is missed, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not take a double dose.
• Regular monitoring of blood pressure, kidney function, and electrolytes (especially potassium, sodium) is recommended during treatment.
• Use only under medical supervision in patients with renal impairment, hepatic impairment, or in the elderly; dose adjustments may be required.

Clinical Benefits:

• Provides effective blood pressure reduction through dual mechanism: vasodilation (candesartan) and mild diuresis (hydrochlorothiazide).
• Helps lower peripheral vascular resistance and fluid overload, supporting better control of essential hypertension.
• Fixed-dose combination improves treatment convenience and may enhance adherence compared with taking two separate medicines.
• By controlling high blood pressure, it contributes to lowering the long-term risk of stroke, heart attack, and other hypertension-related complications when used as part of a comprehensive cardiovascular risk management plan.

Warnings & Contraindications:

• Contraindicated in patients with hypersensitivity to candesartan cilexetil, hydrochlorothiazide, other sulfonamide-derived drugs, or any component of the formulation.
• Contraindicated during pregnancy, especially in the second and third trimesters, due to risk of fetal injury and death. If pregnancy is detected, discontinue immediately and consult a doctor.
• Contraindicated in severe renal impairment, anuria, or severe hepatic impairment/cholestasis unless specifically advised by a specialist.
• Use with caution in patients with renal artery stenosis, heart failure, electrolyte imbalance (hypokalemia, hyponatremia, hypercalcemia), gout, diabetes mellitus, or history of severe allergic reactions.
• Concomitant use with lithium may increase lithium blood levels and toxicity; combination is generally not recommended. If necessary, monitor lithium levels closely.
• Concomitant use with other antihypertensives or diuretics may enhance blood pressure lowering and increase risk of hypotension.
• Non-steroidal anti-inflammatory drugs (nsaids) may reduce the antihypertensive effect and increase risk of renal impairment, especially in dehydrated or elderly patients.
• Concomitant use with potassium-sparing diuretics, potassium supplements, or salt substitutes containing potassium may increase risk of hyperkalemia; monitor serum potassium.
• May cause dizziness or fatigue; use caution when driving or operating machinery until you know how the medicine affects you.
• Consult your doctor before use if pregnant, nursing, planning pregnancy, taking other medications, or if you have kidney disease, liver disease, heart failure, diabetes, or gout.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision; it is a prescription medicine for specific conditions only.
• Keep out of reach of children.

Side Effects:

• Common side effects may include dizziness, headache, fatigue, and mild gastrointestinal discomfort (nausea, abdominal pain).
• Due to the diuretic component, electrolyte disturbances may occur, such as low sodium (hyponatremia), low potassium (hypokalemia), or increased uric acid, which may precipitate gout in susceptible individuals.
• Less common side effects can include hypotension (low blood pressure), especially after the first doses or in volume-depleted patients, palpitations, muscle cramps, or rash.
• Serious but rare side effects may include severe allergic reactions, angioedema (swelling of face, lips, tongue, or throat), significant kidney function deterioration, severe electrolyte imbalance, or visual disturbances. Seek immediate medical attention if these occur.
• If you experience persistent dizziness, fainting, severe dehydration, reduced urine output, or any unusual symptoms, contact your doctor promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Form: Tablet.
• Strength per tablet: candesartan cilexetil 16 mg + hydrochlorothiazide 12.5 mg.
• Pack size: 21 tablets per pack.
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.