Heparin sodium-nile 5000 i.u./ml

Heparin sodium-nile 5000 i.u./ml

Description:

Heparin sodium-nile 5000 i.u./ml is a prescription anticoagulant injectable solution used to prevent and treat blood clots in various medical conditions. It contains heparin sodium, a fast-acting blood thinner that works by enhancing the activity of antithrombin III, thereby inhibiting key clotting factors and reducing the formation and extension of thrombi. This medicine is commonly used in hospitals and clinical settings for the management of venous and arterial thromboembolic disorders and during procedures where anticoagulation is required.

Indications:

• Treatment and prevention of deep vein thrombosis (dvt)
• Treatment and prevention of pulmonary embolism (pe)
• Management of disseminated intravascular coagulation (dic) under specialist supervision
• Treatment and prevention of peripheral arterial embolism
• Atrial fibrillation with risk of embolism (to reduce thromboembolic complications)
• Prevention and treatment of venous thrombosis in high-risk patients (e.g., post-surgery, prolonged immobilization), as directed by a physician
• Anticoagulation during certain medical procedures (e.g., dialysis, some surgeries) as per hospital protocol

Active Ingredients / Key Components:

• Heparin sodium – 5000 international units (i.u.) per ml
• Excipients: The full list of inactive ingredients (e.g., preservatives, stabilizers, buffer components) is not available in the provided information. Please refer to the official package leaflet for complete excipient details.

Dosage & Administration / How to Use:

• Heparin sodium-nile 5000 i.u./ml must be used only under medical supervision.
• Dosage, route (intravenous or subcutaneous), and duration of therapy are determined individually by the treating physician based on the indication, body weight, renal function, and coagulation test results.
• For treatment of acute thromboembolic disorders, an initial intravenous bolus dose may be followed by continuous intravenous infusion or regular subcutaneous injections, according to hospital protocol.
• For prophylaxis of venous thrombosis, lower-dose subcutaneous regimens are typically used; exact dosing must follow the physician’s prescription and current clinical guidelines.
• Do not self-inject unless you have been clearly instructed and trained by a healthcare professional on the correct technique and dose.
• Do not adjust the dose or stop treatment without consulting your doctor, as sudden interruption may increase the risk of thrombosis.
• Regular monitoring of coagulation parameters (such as aptt or anti-xa levels, as appropriate) and platelet counts is usually required during therapy.
• Use only clear, particle-free solution. Do not use if the ampoule is damaged, cracked, or the solution appears discolored or contains particles.

Clinical Benefits:

• Rapid anticoagulant effect to help prevent the formation of new blood clots.
• Reduces the extension and propagation of existing thrombi in veins and arteries.
• Helps lower the risk of serious complications such as pulmonary embolism, stroke, and organ damage due to emboli.
• Supports safe anticoagulation during high-risk medical procedures and periods of immobilization under professional supervision.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to heparin or any of the excipients.
• Contraindicated in patients with active major bleeding, severe thrombocytopenia, or a history of heparin-induced thrombocytopenia (hit) unless under strict specialist supervision.
• Use with extreme caution in patients with bleeding disorders, recent surgery, trauma, peptic ulcer, severe uncontrolled hypertension, liver disease, kidney impairment, or conditions predisposing to bleeding.
• Concomitant use with other anticoagulants, antiplatelet agents, thrombolytics, or nsaids may increase bleeding risk; such combinations must be managed and monitored by a physician.
• Spinal/epidural anesthesia or lumbar puncture in patients receiving heparin increases the risk of spinal/epidural hematoma, which may result in long-term or permanent paralysis; follow specialist guidance strictly.
• Consult your doctor before use if pregnant, nursing, taking any medications, or if you have medical conditions such as bleeding disorders, liver disease, kidney disease, hypertension, or recent surgery.
• Not intended to diagnose, treat, cure, or prevent any disease without a physician’s prescription and supervision.
• Keep out of reach of children.
• Do not use beyond the expiry date printed on the pack. Do not share this medication with others.

Side Effects:

• Common side effects: Mild bleeding or bruising at the injection site, minor nosebleeds, or easy bruising may occur.
• Serious side effects: Major bleeding (e.g., gastrointestinal bleeding, intracranial hemorrhage), black or bloody stools, blood in urine, coughing or vomiting blood, sudden severe headache, weakness, dizziness, or vision changes – seek immediate medical attention.
• Heparin-induced thrombocytopenia (hit): A serious immune-mediated drop in platelet count that may paradoxically increase the risk of thrombosis; symptoms may include new or worsening clots, skin changes at the injection site, or unusual bleeding. Immediate medical evaluation is required if suspected.
• Allergic reactions: Rash, itching, swelling, severe dizziness, or difficulty breathing require urgent medical care.
• Long-term use at high doses may rarely cause osteoporosis or hair loss; monitoring is advised in prolonged therapy.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not freeze. Store at the temperature range specified on the outer carton or leaflet. Discard any unused portion of an opened ampoule; do not store partially used ampoules.

Specifications:

• Product type: Injectable anticoagulant medicine (parenteral solution)
• Strength: 5000 i.u. heparin sodium per 1 ml solution
• Pack size: 100 ampoules (exact volume per ampoule is not specified in the provided information; refer to the pack for details)
• Route of administration: Intravenous or subcutaneous, as directed by a healthcare professional

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.