EPIROVASTIN 20MG 14TAB

EPIROVASTIN 20MG 14TAB

Description:

EPIROVASTIN 20 mg 14 film-coated tablets is a prescription lipid-lowering medicine containing rosuvastatin, a statin (HMG-CoA reductase inhibitor) used to reduce high cholesterol and triglycerides and to help prevent cardiovascular events. It works by inhibiting cholesterol synthesis in the liver, lowering low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL), while modestly increasing high-density lipoprotein (HDL). EPIROVASTIN is indicated as part of a comprehensive cardiovascular risk-reduction plan that includes diet, exercise, and lifestyle modification.

Indications:

• Treatment of primary hypercholesterolemia (including familial and non-familial) and mixed dyslipidemia as an adjunct to diet.
• Treatment of homozygous familial hypercholesterolemia as an adjunct to diet and other lipid-lowering treatments (such as LDL apheresis) or when such treatments are not available.
• Reduction of elevated total cholesterol, LDL-cholesterol, non-HDL cholesterol, apolipoprotein B, and triglycerides.
• Increase of HDL-cholesterol in patients with dyslipidemia.
• Prevention of major cardiovascular events (such as myocardial infarction, stroke, or revascularization procedures) in patients at high risk of atherosclerotic cardiovascular disease, as part of an overall risk-management strategy.

Active Ingredients / Key Components:

• Rosuvastatin (as rosuvastatin calcium) – 20 mg per film-coated tablet.
• Other inactive ingredients (excipients, film-coating agents, stabilizers) are present but specific composition is not available in the provided information.

Dosage & Administration / How to Use:

• Dosage must always be individualized by a physician based on treatment goals, baseline lipid levels, and patient response.
• Typical adult starting dose for hypercholesterolemia is 5–10 mg once daily; some patients may be started on 20 mg once daily depending on cardiovascular risk and baseline LDL levels. This product strength provides 20 mg per tablet.
• Usual dose range: 5–40 mg once daily. The 40 mg dose is reserved for patients with severe hypercholesterolemia and high cardiovascular risk who do not achieve goals on lower doses and requires close medical supervision.
• Take once daily, at the same time each day, with or without food. Swallow the tablet whole with water; do not crush or chew.
• Continue standard cholesterol-lowering diet before and during treatment.
• In patients with renal or hepatic impairment, in the elderly, or in those taking interacting medicines, lower starting doses and maximum doses may be required; follow physician instructions strictly.
• If a dose is missed, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not double the dose.

Clinical Benefits:

• Effectively lowers LDL-cholesterol and non-HDL cholesterol, helping to control high cholesterol levels.
• Reduces hepatic synthesis of VLDL and lowers plasma triglyceride levels, improving overall lipid profile.
• Increases HDL-cholesterol, contributing to better cardiovascular protection.
• Helps reduce the risk of atherosclerotic cardiovascular events such as heart attack and stroke when used as part of a comprehensive risk-reduction strategy.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to rosuvastatin or any component of the formulation.
• Contraindicated in active liver disease or unexplained persistent elevations of serum transaminases.
• Contraindicated during pregnancy and breastfeeding; statins may harm the fetus and may pass into breast milk.
• Use with caution in patients with a history of liver disease, heavy alcohol use, renal impairment, hypothyroidism, or personal/family history of hereditary muscle disorders.
• Risk of myopathy and rhabdomyolysis increases with higher doses, advanced age, renal impairment, uncontrolled hypothyroidism, and concomitant use of certain drugs (e.g., some fibrates, niacin at lipid-lowering doses, certain antivirals, cyclosporine). Inform your doctor about all medications and supplements you are taking.
• Periodic monitoring of liver function tests and creatine kinase (CK) may be recommended, especially after dose increases or if symptoms occur.
• Stop treatment and seek medical advice immediately if you experience unexplained muscle pain, tenderness, weakness, or dark-colored urine, particularly if accompanied by malaise or fever.
• Consult your doctor before use if pregnant, nursing, planning pregnancy, taking other medications, or if you have medical conditions such as liver disease, kidney disease, thyroid disorders, diabetes, or muscle disorders.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include headache, dizziness, abdominal pain, constipation, nausea, muscle pain (myalgia), and weakness.
• Less common side effects can include itching, rash, pruritus, joint pain, and elevated liver enzymes on blood tests.
• Serious but rare side effects include myopathy, rhabdomyolysis (severe muscle breakdown) with or without acute kidney failure, severe liver injury, and hypersensitivity reactions (such as angioedema).
• Some patients may experience increased blood sugar levels or new-onset diabetes, especially those already at risk.
• Seek immediate medical attention if you notice severe muscle pain, dark urine, yellowing of the skin or eyes (jaundice), severe abdominal pain, difficulty breathing, facial or tongue swelling, or any signs of a severe allergic reaction.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Strength: 20 mg rosuvastatin per film-coated tablet.
• Form: Film-coated tablet.
• Pack size: 14 tablets per pack.
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.