Alfacareno Oral Drops

Alfacareno Oral Drops

Description:

Alfacareno Oral Drops 2 mcg/ml is a prescription vitamin d analogue (alfacalcidol) used as a systemic medicine to manage disorders of calcium and phosphate metabolism. It is indicated in conditions such as hypocalcaemia, hypoparathyroidism, hypophosphataemia, renal osteodystrophy, and osteomalacia, where active vitamin d support is required to improve bone mineralization and maintain healthy bones and joints. Each 10 ml bottle of oral drops allows precise dose adjustment under medical supervision, making it suitable for long-term management of chronic bone and mineral disorders.

Indications:

• Treatment and prevention of hypocalcaemia (low blood calcium levels).
• Management of hypoparathyroidism and related disturbances of calcium and phosphate balance.
• Treatment of hypophosphataemia associated with vitamin d–dependent conditions (as prescribed by the physician).
• Management of renal osteodystrophy in patients with chronic kidney disease.
• Treatment of osteomalacia (softening of the bones) due to vitamin d deficiency or impaired activation.
• Support of bone health and mineralization in patients requiring active vitamin d analogue therapy.

Active Ingredients / Key Components:

• Alfacalcidol – 2 mcg/ml (active vitamin d analogue; exact excipients and their concentrations , please check the product leaflet or the manufacturer’s official website).

Dosage & Administration / How to Use:

• Use only under medical supervision and according to your doctor’s prescription.
• Adults (oral): Typical recommended starting dose is 1 mcg/day. Maintenance dose usually ranges from 0.25–1 mcg/day, adjusted based on clinical response and laboratory values (serum calcium, phosphate, and parathyroid hormone levels).
• The total daily dose in drops should be calculated by the prescribing physician according to the concentration 2 mcg/ml. Your pharmacist or doctor will explain how many drops correspond to your prescribed dose.
• Take the drops by mouth. They may be taken with or without food, preferably at the same time each day.
• Swallow directly or mix the prescribed number of drops with a small amount of water or other suitable liquid, as advised by your healthcare provider.
• Do not change the dose, frequency, or duration of use without consulting your doctor.
• Regular monitoring of blood calcium, phosphate, and kidney function is essential during treatment to avoid hypercalcaemia and other complications.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.

Clinical Benefits:

• Helps normalize and maintain serum calcium and phosphate levels in patients with impaired vitamin d activation.
• Supports bone mineralization and helps manage bone pain and weakness associated with osteomalacia and renal osteodystrophy.
• Assists in reducing complications related to chronic hypocalcaemia, such as muscle cramps, tetany, and neuromuscular irritability.
• Provides an active form of vitamin d analogue that bypasses hepatic 25-hydroxylation, beneficial in patients with impaired vitamin d metabolism.

Warnings & Contraindications:

• Use only under the supervision of a physician experienced in managing calcium and bone metabolism disorders.
• Contraindicated in patients with hypercalcaemia, hyperphosphataemia (except when due to hypoparathyroidism), vitamin d toxicity, or known hypersensitivity to alfacalcidol or any component of the formulation.
• Use with extreme caution in patients with severe renal impairment, nephrolithiasis (kidney stones), or sarcoidosis, and in those at risk of hypercalcaemia.
• Frequent monitoring of serum calcium, phosphate, alkaline phosphatase, and renal function is required; dose adjustments may be necessary.
• Concomitant use with other vitamin d products, calcium supplements, or thiazide diuretics may increase the risk of hypercalcaemia; inform your doctor about all medicines and supplements you are taking.
• Consult your doctor before use if pregnant, nursing, planning pregnancy, taking other medications, or having medical conditions such as kidney disease, heart disease, or a history of kidney stones.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision; it is a prescription medicine for specific indications.
• Keep out of reach of children.
• Do not exceed the prescribed dose; prolonged excessive intake may lead to serious hypercalcaemia and related complications (kidney damage, cardiac arrhythmias).

Side Effects:

• Common side effects may include nausea, vomiting, loss of appetite, constipation, abdominal discomfort, headache, or dry mouth, often related to elevated calcium levels.
• Signs of hypercalcaemia may include excessive thirst, frequent urination, weakness, drowsiness, confusion, bone pain, or irregular heartbeat. Contact your doctor immediately if these occur.
• Rarely, allergic reactions such as rash, itching, swelling, or breathing difficulties may occur. Seek urgent medical attention if any signs of severe allergy appear.
• Long-term uncontrolled hypercalcaemia can lead to kidney stones, calcification of soft tissues, and renal impairment; regular laboratory monitoring is essential.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the package. Do not freeze.

Specifications:

• Product type: Oral vitamin d analogue medicine (alfacalcidol drops).
• Concentration: 2 mcg/ml alfacalcidol.
• Form: Oral drops.
• Pack size: 10 ml bottle.
• Intended use: Management of calcium and bone metabolism disorders under medical supervision.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.