Amrizole 500 Mg Tablets

Amrizole 500 Mg Tablets

Description:

Amrizole 500 mg Tablets is a prescription oral antibiotic and antiprotozoal medicine containing metronidazole. It is used to treat a wide range of protozoal infections and anaerobic bacterial infections, particularly in the gastrointestinal tract, genital tract, oral cavity, and post-surgical settings. Amrizole 500 mg is commonly prescribed for amoebiasis, giardiasis, trichomonas vaginitis, and anaerobic infections, helping to eliminate the causative organisms and relieve associated symptoms such as abdominal pain, diarrhea, and vaginal discharge. This product is intended for adult use under medical supervision.

Indications:

• Amoebiasis (intestinal and extra-intestinal), including acute and chronic amoebic dysentery and amoebic liver abscess.
• Giardiasis (Giardia lamblia infection) causing diarrhea, abdominal cramps, and malabsorption.
• Trichomonas vaginitis and urogenital trichomoniasis.
• Pseudomembranous enterocolitis caused by susceptible organisms.
• Anaerobic bacterial infections, including intra-abdominal infections, pelvic infections, post-operative anaerobic infections, brain abscess, and endocarditis, as part of appropriate antibiotic therapy.
• Helicobacter pylori-associated infections as part of combination eradication regimens (as directed by a physician).
• Acute ulcerative gingivitis and other oral anaerobic infections.

Active Ingredients / Key Components:

• Metronidazole – 500 mg per tablet.
• Excipients: Other inactive ingredients (tablet core and coating) are present but specific excipient names and concentrations , please check the product leaflet or the manufacturer’s official website.

Dosage & Administration / How to Use:

• Dosage must always be determined by a physician based on the type and severity of infection, age, and body weight.
• Typical adult doses (for guidance only – follow your doctor’s instructions):
  • Amoebiasis: Common regimens use metronidazole 500 mg 2–3 times daily for 5–10 days.
  • Giardiasis: Often 250–500 mg 2–3 times daily for 5–7 days.
  • Trichomonas vaginitis: Single high dose or divided doses over several days, as prescribed.
  • Anaerobic infections: Initial higher doses may be followed by 500 mg every 8 hours, as directed by the physician.
• Route of administration: Oral, swallowed whole with a glass of water. Do not crush or chew unless your doctor or pharmacist advises otherwise.
• May be taken with or after food to reduce stomach upset, unless otherwise directed.
• Duration of treatment: Complete the full course prescribed, even if symptoms improve earlier, to prevent recurrence and resistance.
• If a dose is missed: Take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Avoid alcohol during treatment and for at least 48 hours after the last dose due to risk of a disulfiram-like reaction (flushing, nausea, vomiting, headache).

Clinical Benefits:

• Effectively treats protozoal infections such as amoebiasis, giardiasis, and trichomoniasis by directly killing the causative organisms.
• Provides strong activity against many anaerobic bacteria, helping manage serious intra-abdominal, pelvic, and post-surgical infections.
• Helps relieve symptoms associated with gastrointestinal and genital infections, including diarrhea, abdominal pain, and abnormal vaginal discharge.
• Supports comprehensive treatment regimens for Helicobacter pylori and certain oral infections (e.g., ulcerative gingivitis) when used as part of combination therapy.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to metronidazole or other nitroimidazole derivatives.
• Use with caution in patients with severe liver impairment, blood dyscrasias, or central nervous system disorders (e.g., epilepsy, peripheral neuropathy). Dose adjustment may be required.
• Avoid alcohol and alcohol-containing products during treatment and for at least 48 hours after stopping metronidazole due to risk of severe nausea, vomiting, flushing, and palpitations.
• Prolonged or repeated use may increase the risk of peripheral neuropathy or other neurologic effects; inform your doctor if you experience numbness, tingling, or weakness.
• May interact with anticoagulants (e.g., warfarin), lithium, phenytoin, phenobarbital, and other medicines. Inform your doctor about all medications and supplements you are taking.
• Consult your doctor before use if pregnant or planning pregnancy. Metronidazole should be used in pregnancy only if clearly needed and prescribed by a physician.
• Metronidazole is excreted in breast milk; breastfeeding women should consult a healthcare provider before use.
• May cause dizziness, confusion, or visual disturbances; avoid driving or operating machinery if affected.
• Consult your doctor before use if you have liver disease, kidney disease, blood disorders, neurological disease, or a history of seizures.
• Keep out of reach of children.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision.

Side Effects:

• Common side effects: Nausea, vomiting, abdominal discomfort, diarrhea or constipation, metallic taste in the mouth, loss of appetite, headache, and dry mouth.
• Less common side effects: Dizziness, fatigue, dark-colored urine, oral thrush, or vaginal candidiasis due to alteration of normal flora.
• Serious side effects (seek immediate medical attention): Severe allergic reactions (rash, itching, swelling of face or throat, difficulty breathing), seizures, confusion, severe dizziness, peripheral neuropathy (numbness, tingling, or pain in hands or feet), severe abdominal pain, or persistent vomiting.
• If you experience any unusual or persistent symptoms, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the tablets in their original blister or container, tightly closed. Do not use after the expiry date printed on the pack. Keep out of reach of children.

Specifications:

• Product form: Tablets for oral use.
• Strength: 500 mg metronidazole per tablet.
• Pack size: 20 tablets per pack (amrizole 500 mg 20 tabs).
• Intended use: Prescription medicine for treatment of protozoal and anaerobic bacterial infections in adults, as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.