Azrolid 500 Mg 3 Tablets

Azrolid 500 Mg 3 Tablets

Description:

Azrolid 500 mg 3 tablets is a prescription systemic antibiotic containing azithromycin, a semi-synthetic macrolide of the azalide class. It is used to treat a wide range of bacterial infections, particularly of the respiratory tract, skin and soft tissues, and certain sexually transmitted and gastrointestinal infections. Azithromycin works by binding to the 50s subunit of bacterial ribosomes, inhibiting RNA-dependent protein synthesis and stopping bacterial growth. Azrolid is intended for use under medical supervision in adults and adolescents as directed by a healthcare professional.

Indications:

• Respiratory tract infections (such as bronchitis, community-acquired pneumonia, pharyngitis, tonsillitis) caused by susceptible bacteria.
• Skin and soft tissue infections (such as uncomplicated skin infections, cellulitis, and infected wounds) due to susceptible organisms.
• Typhoid fever (enteric fever) as part of appropriate antibiotic therapy.
• Uncomplicated gonorrhoea (as a single-dose regimen when recommended by a physician).
• Granuloma inguinale (donovanosis) until complete healing of lesions, as directed by a doctor.
• Chancroid and chlamydial urethritis or cervicitis (as a single-dose regimen when indicated).
• Prophylaxis of disseminated Mycobacterium avium complex (MAC) infections in at-risk patients, and treatment or secondary prophylaxis in combination with other antimycobacterial agents, as per specialist guidance.
• Other infections caused by azithromycin-sensitive bacteria as determined by culture, sensitivity testing, and physician judgment.

Active Ingredients / Key Components:

• Azithromycin – 500 mg per film-coated tablet.
• Other tablet excipients: exact excipient composition and concentrations , please check the product leaflet or the manufacturer’s official website. Refer to the package leaflet for full excipient list.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician. Do not self-medicate or change the dose without medical advice.
• Adults (typical regimens, to be confirmed by your doctor):
  • Respiratory tract, skin and soft tissue infections: 500 mg once daily for 3 days, or 500 mg on day 1 followed by 250 mg once daily on days 2 to 5.
  • Typhoid fever: 500 mg once daily for 7 days, or as directed by your physician.
  • Uncomplicated gonorrhoea: 2 g as a single oral dose (may require combination therapy as per guidelines).
  • Granuloma inguinale: initial dose 1 g on day 1, then 500 mg once daily until all lesions have completely healed.
  • Chancroid / chlamydial urethritis or cervicitis: 1 g as a single oral dose, as directed by a doctor.
  • Prophylaxis of disseminated MAC infection: 1.2 g once weekly.
  • Treatment or secondary prophylaxis of MAC: 500 mg once daily in combination with other antimycobacterial agents, under specialist supervision.
• Azrolid tablets are usually taken once daily, preferably at the same time each day.
• Can be taken with or without food; however, taking with food may help reduce gastrointestinal discomfort.
• Swallow the tablet whole with a sufficient amount of water. Do not crush or chew unless advised by your doctor.
• Complete the full prescribed course even if symptoms improve early, to prevent relapse and antibiotic resistance.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed dose.
• Dosage in children, elderly patients, and those with kidney or liver impairment must be determined by a physician. Do not use in children without medical advice.

Clinical Benefits:

• Provides broad-spectrum antibacterial activity against many common respiratory, skin, and sexually transmitted pathogens.
• Convenient once-daily dosing and short treatment courses (often 3–5 days) support better adherence compared with some other antibiotics.
• High tissue penetration and long half-life (approximately 68 hours) allow sustained antibacterial levels at the site of infection.
• Effective in the management of community-acquired pneumonia, bronchitis, and ENT infections when caused by susceptible organisms.
• Offers targeted therapy for certain sexually transmitted infections (such as chlamydial infections and uncomplicated gonorrhoea) as per current guidelines.
• Useful in prophylaxis and treatment of disseminated MAC infections in high-risk patients under specialist care.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to azithromycin, other macrolide or ketolide antibiotics, or any component of the formulation.
• Use with caution in patients with existing liver disease or hepatic dysfunction; cases of severe hepatotoxicity have been reported with azithromycin. Discontinue and seek medical help if signs of hepatitis (fatigue, jaundice, dark urine, abdominal pain) occur.
• Use with caution in patients with renal impairment; dose adjustment may be required in severe renal dysfunction as determined by a physician.
• Azithromycin may prolong the QT interval; use with caution in patients with known QT prolongation, history of torsades de pointes, clinically relevant bradycardia, cardiac arrhythmias, uncompensated heart failure, or those taking other QT-prolonging drugs.
• Use with caution in patients with electrolyte disturbances (such as hypokalemia or hypomagnesemia) which may increase the risk of arrhythmias.
• Antibiotic-associated colitis (including Clostridioides difficile-associated diarrhea) may occur. Persistent or severe diarrhea should be reported immediately to a doctor.
• May cause allergic reactions, including severe reactions such as angioedema and anaphylaxis. Stop treatment and seek emergency medical attention if rash, swelling, or breathing difficulties occur.
• Use during pregnancy and breastfeeding only if clearly needed and prescribed by a physician. Discuss potential risks and benefits with your doctor.
• May interact with other medications (e.g., certain antiarrhythmics, warfarin, digoxin, ergot derivatives, some antacids). Inform your doctor and pharmacist about all medicines and supplements you are taking.
• Do not use for viral infections such as the common cold or influenza; inappropriate use promotes antibiotic resistance.
• Consult your doctor before use if pregnant, nursing, taking medications, or have medical conditions such as liver disease, kidney disease, heart disease, arrhythmias, or electrolyte imbalances.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include nausea, vomiting, abdominal pain, diarrhea, flatulence, indigestion, and headache.
• Less common side effects can include dizziness, fatigue, taste disturbances, skin rash, itching, and mild elevations in liver enzymes.
• Serious side effects (seek immediate medical attention): severe allergic reactions (swelling of face, lips, tongue, or throat; difficulty breathing), severe skin reactions (Stevens–Johnson syndrome, toxic epidermal necrolysis), severe or persistent diarrhea (possible C. difficile colitis), jaundice or other signs of liver problems, palpitations or irregular heartbeat, chest pain, or fainting.
• If any side effect is severe, persistent, or worrying, stop the medication and contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature stated on the package insert (specific storage temperature information is not available in the provided data; refer to the original pack).

Specifications:

• Product type: Prescription systemic antibiotic medicine.
• Active ingredient: azithromycin 500 mg per film-coated tablet.
• Form: Film-coated tablets (f.c. tabs).
• Pack size: 3 tablets per pack.
• Route of administration: Oral (by mouth).
• Intended users: Adults and adolescents as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.