Azrolid syrup 200 mg/5 ml (22.5ml )

Azrolid syrup 200 mg/5 ml (22.5ml )

Description:

Azrolid syrup 200 mg/5 ml is an oral antibiotic medicine containing azithromycin, a semi-synthetic macrolide of the azalide class. It is used to treat a wide range of bacterial infections, particularly of the respiratory tract, skin and soft tissues, and certain sexually transmitted infections. The syrup form and pediatric-strength concentration make it suitable for children and adults who prefer or require a liquid dosage form. Azithromycin works by binding to the 50s subunit of bacterial ribosomes, inhibiting RNA-dependent protein synthesis and stopping bacterial growth. This product is intended for use under medical supervision and according to a doctor’s prescription.

Indications:

• Upper and lower respiratory tract infections caused by susceptible organisms (e.g., pharyngitis, tonsillitis, sinusitis, bronchitis, pneumonia).
• Skin and soft tissue infections (e.g., uncomplicated skin infections, cellulitis, impetigo) due to susceptible bacteria.
• Otitis media (middle ear infection) in children, as directed by a physician.
• Certain sexually transmitted infections such as uncomplicated chlamydial urethritis and chancroid, as prescribed.
• Typhoid fever and other systemic infections caused by susceptible organisms, according to physician guidance.
• Prevention and treatment of disseminated Mycobacterium avium complex (MAC) infections in appropriate patients, in combination with other antimycobacterial agents, as directed by a specialist.
• Other bacterial infections where azithromycin is indicated and prescribed by a healthcare professional.

Active Ingredients / Key Components:

• Azithromycin – 200 mg per 5 ml oral suspension (equivalent to 40 mg/ml).
• Each bottle: 22.5 ml of powder for oral suspension after reconstitution (exact total azithromycin content per bottle is not specified on the label and may vary by pack size; refer to package insert).
• Excipients: Specific inactive ingredients (sweeteners, suspending agents, flavoring agents, preservatives) are not listed in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.). Please refer to the official package leaflet for the full excipient list.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician. Dosage depends on the type and severity of infection, patient age, and body weight.
• General adult oral dosing (for reference, usually with tablets or equivalent total dose):
  • Respiratory tract, skin and soft tissue infections: 500 mg once daily for 3 days, or 500 mg on day 1 followed by 250 mg once daily on days 2–5 (total 1.5 g).
  • Typhoid fever: 500 mg once daily for 7 days.
  • Uncomplicated gonorrhoea: 2 g as a single dose.
  • Granuloma inguinale: 1 g on day 1, then 500 mg once daily until all lesions have completely healed.
  • Chancroid / chlamydial urethritis: 1 g as a single dose.
  • Prophylaxis of disseminated MAC infection: 1.2 g once weekly.
  • Treatment or secondary prophylaxis of MAC (with other antimycobacterials): 500 mg once daily.
• Pediatric dosing: Typically based on body weight (mg/kg/day) using the 200 mg/5 ml suspension. The exact dose, frequency, and duration must be determined by the pediatrician. Do not calculate or adjust the dose without medical advice.
• Shake the bottle well before each use to ensure uniform suspension.
• Measure the dose accurately using the provided measuring syringe or cup; do not use household teaspoons.
• Azithromycin may be taken with or without food; however, taking it with food may reduce gastrointestinal discomfort.
• Take at the same time each day to maintain consistent blood levels.
• Complete the full course of therapy even if symptoms improve earlier, unless your doctor advises otherwise.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed dose.

Clinical Benefits:

• Broad-spectrum antibacterial activity against many common respiratory, skin, and soft tissue pathogens.
• Convenient once-daily dosing, which may improve treatment adherence compared to multiple daily doses.
• Liquid syrup form facilitates use in children and adults who have difficulty swallowing tablets or capsules.
• Long half-life (approximately 68 hours) allows shorter treatment courses for many infections while maintaining effective tissue levels.
• Effective in the management of certain sexually transmitted infections and MAC-related conditions when used as directed.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to azithromycin, erythromycin, other macrolide or ketolide antibiotics, or any component of the formulation.
• Use with caution in patients with severe liver impairment; azithromycin is primarily eliminated by the liver.
• Use with caution in patients with pre-existing heart conditions (e.g., QT prolongation, arrhythmias, bradycardia) or those taking other drugs known to prolong the QT interval.
• Use with caution in patients with significant renal impairment.
• Antibiotic-associated diarrhea and Clostridioides difficile-associated diarrhea may occur; discontinue and seek medical advice if severe, persistent, or bloody diarrhea develops.
• Overuse or inappropriate use of antibiotics may promote the development of resistant bacteria; use only when prescribed and for bacterial infections, not viral illnesses such as common cold or flu.
• Consult your doctor before use if pregnant or nursing; azithromycin should be used during pregnancy and lactation only if clearly needed and prescribed.
• Inform your doctor about all medications you are taking, especially antiarrhythmics, other macrolides, fluoroquinolones, antipsychotics, antidepressants, or drugs affecting liver enzymes.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision and prescription.
• Keep out of reach of children.

Side Effects:

• Common side effects: nausea, vomiting, abdominal pain, diarrhea, flatulence, indigestion, and mild headache.
• Less common side effects: dizziness, taste disturbances, rash, itching, or photosensitivity.
• Serious side effects (seek immediate medical attention): severe allergic reactions (swelling of face, lips, tongue, or throat; difficulty breathing), severe skin reactions (Stevens–Johnson syndrome, toxic epidermal necrolysis), severe or persistent diarrhea, jaundice or signs of liver dysfunction (dark urine, yellowing of skin or eyes), palpitations or irregular heartbeat, chest pain, or fainting.
• If any unexpected or bothersome side effects occur, stop using the product and consult your doctor or pharmacist.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. After reconstitution (if supplied as powder for suspension), follow the storage conditions and expiry period stated in the package insert (e.g., usually refrigerated or at room temperature for a limited number of days). Do not use after the expiry date printed on the pack.

Specifications:

• Product type: Prescription antibiotic medicine (oral suspension).
• Active ingredient concentration: azithromycin 200 mg/5 ml (40 mg/ml).
• Form: Syrup / powder for oral suspension after reconstitution.
• Pack size: 22.5 ml bottle (exact usable volume after reconstitution as per manufacturer’s instructions).
• Intended users: Adults and children as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.