Bone Care Alfacalcidol 0.25 Mcg

Bone Care Alfacalcidol 0.25 mcg

Description:

Bone Care Alfacalcidol 0.25 mcg is an oral prescription vitamin D analogue used as a medicine to manage disorders of calcium and bone metabolism. Each capsule contains alfacalcidol, an active metabolite of vitamin D, which is rapidly converted in the body to calcitriol, the hormonally active form of vitamin D3. It is commonly prescribed in patients with chronic kidney disease, hypoparathyroidism, and other conditions that cause low calcium levels and bone demineralization. By improving calcium and phosphate balance, Bone Care Alfacalcidol 0.25 mcg helps support bone mineralization, reduce bone pain, and prevent complications such as osteomalacia and renal osteodystrophy.

Indications:

• Treatment and prevention of hypocalcaemia (low blood calcium levels) associated with impaired vitamin D activation.
• Management of hypoparathyroidism (reduced parathyroid hormone function) leading to disturbed calcium and phosphate balance.
• Treatment of hypophosphataemia (low blood phosphate levels) related to vitamin D metabolism disorders.
• Management of renal osteodystrophy in patients with chronic renal failure, especially those on dialysis.
• Treatment of osteomalacia (softening of the bones) due to vitamin D deficiency or impaired vitamin D activation.
• Supportive therapy in bone health where active vitamin D is required to enhance calcium absorption and bone mineralization, as directed by a physician.

Active Ingredients / Key Components:

• Alfacalcidol – 0.25 mcg per capsule.
• Other inactive ingredients/excipients: Information on the full excipient list is not available in the provided data. Please refer to the package insert for complete details.

Dosage & Administration / How to Use:

• Bone Care Alfacalcidol 0.25 mcg capsules are for oral use only and must be taken exactly as prescribed by a physician.
• Typical adult oral dosing (general reference): The usual starting dose of alfacalcidol in adults is 1 mcg per day, with a maintenance dose generally ranging from 0.25 mcg to 1 mcg per day, adjusted according to clinical response, serum calcium, and phosphate levels. Your doctor will determine the exact dose and may use multiple capsules to reach the prescribed daily dose.
• Capsules may be taken with or without food, preferably at the same time each day to maintain consistent blood levels.
• Swallow the capsule whole with a glass of water; do not crush or chew unless your doctor or pharmacist advises otherwise.
• Regular monitoring of serum calcium, phosphate, alkaline phosphatase, and renal function is essential. Your doctor may adjust the dose or temporarily stop treatment based on these results.
• If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed one.
• Do not change the dose, stop, or restart the medication without consulting your healthcare provider.

Clinical Benefits:

• Helps correct and maintain normal calcium levels in patients with impaired vitamin D activation or hypoparathyroidism.
• Supports proper bone mineralization, helping to manage and prevent osteomalacia and renal osteodystrophy.
• Improves intestinal absorption of calcium and phosphate, contributing to stronger bones and reduced risk of bone pain and fractures.
• Provides an active form of vitamin D suitable for patients with chronic kidney disease who cannot adequately convert standard vitamin D to its active form.

Warnings & Contraindications:

• Use only under medical supervision. Alfacalcidol is a potent active vitamin D analogue and inappropriate dosing may cause serious hypercalcaemia.
• Contraindications: Known hypersensitivity to alfacalcidol, other vitamin D analogues, or any component of the formulation; existing hypercalcaemia; evidence of vitamin D toxicity.
• Use with extreme caution in patients with renal impairment, nephrolithiasis (kidney stones), arteriosclerosis, sarcoidosis, or other granulomatous diseases, as they may be more prone to hypercalcaemia.
• Monitor serum calcium, phosphate, and renal function regularly during therapy. Treatment may need to be adjusted or temporarily stopped if hypercalcaemia or hyperphosphataemia occurs.
• Concomitant use with other vitamin D preparations, calcium supplements, or thiazide diuretics may increase the risk of hypercalcaemia; inform your doctor about all medicines and supplements you are taking.
• Consult your doctor before use if pregnant or nursing; dosing and monitoring must be individualized in pregnancy and lactation.
• Patients with liver disease, cardiovascular disease, or those on digitalis (cardiac glycosides) should use with caution, as hypercalcaemia may precipitate arrhythmias.
• Not intended to diagnose, treat, cure, or prevent any disease without a physician’s supervision; this is a prescription medicine and must be used according to medical advice.
• Keep out of reach of children.

Side Effects:

• Common side effects (usually related to elevated calcium levels): nausea, vomiting, loss of appetite, constipation, abdominal pain, dry mouth, metallic taste, headache, dizziness, fatigue, muscle or bone pain.
• Signs of hypercalcaemia: increased thirst, frequent urination, weakness, confusion, drowsiness, pruritus, and in severe cases, cardiac rhythm disturbances. If these occur, contact your doctor immediately.
• Less common/serious side effects: kidney stone formation, worsening of renal function, calcification of soft tissues, hypertension, and arrhythmias, especially in patients taking digitalis.
• Stop the medication and seek urgent medical attention if you experience severe or persistent side effects, signs of allergic reaction (rash, itching, swelling of face or throat, difficulty breathing), or symptoms suggestive of severe hypercalcaemia.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature specified on the package insert, and protect from excessive heat and moisture.

Specifications:

• Form: Oral capsules.
• Strength: 0.25 mcg alfacalcidol per capsule.
• Pack size: 30 capsules per pack.
• Intended use: Prescription medicine for disorders of calcium and bone metabolism, as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.