Candalkan Plus 16/12.50 Mg

Candalkan Plus 16/12.50 Mg

Description:

Candalkan Plus 16/12.50 mg is a prescription antihypertensive medicine combining an angiotensin II receptor blocker (ARB) and a thiazide diuretic. It is formulated as film‑coated tablets for the long‑term management of high blood pressure (hypertension) in adults. By blocking the effects of angiotensin II and promoting gentle diuresis, Candalkan Plus helps lower elevated blood pressure, reduce cardiovascular risk, and support overall heart and vascular health when used as part of a comprehensive hypertension treatment plan prescribed by a physician.

Indications:

• Treatment of essential hypertension (high blood pressure) in adults.
• Indicated in patients whose blood pressure is not adequately controlled with candesartan or hydrochlorothiazide alone.
• Helps reduce the risk of hypertension-related complications such as stroke, heart attack, and kidney damage when used regularly under medical supervision.

Active Ingredients / Key Components:

• Candesartan cilexetil – 16 mg per film‑coated tablet (angiotensin II receptor antagonist / ARB).
• Hydrochlorothiazide – 12.5 mg per film‑coated tablet (thiazide diuretic).
• Other tablet excipients (film‑coating agents, fillers, binders, etc.) are present but detailed composition and concentrations , please check the product leaflet or the manufacturer’s official website.

Dosage & Administration / How to Use:

• Candalkan Plus 16/12.50 mg is for oral use only and should be taken exactly as prescribed by your doctor.
• Usual adult dose: one film‑coated tablet once daily, preferably at the same time each day. The exact dose and duration are determined by the treating physician based on blood pressure response and clinical condition.
• Tablets may be taken with or without food. Swallow whole with a glass of water; do not crush or chew unless your doctor or pharmacist advises otherwise.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed tablet.
• Do not stop taking Candalkan Plus suddenly without consulting your doctor, as uncontrolled blood pressure can increase the risk of serious cardiovascular events.
• Regular monitoring of blood pressure, kidney function, and electrolytes (especially potassium and sodium) is recommended during treatment.

Clinical Benefits:

• Effectively lowers high blood pressure by combining two complementary mechanisms: blockade of angiotensin II (vasodilation) and mild diuresis (increased excretion of salt and water).
• Reduces peripheral vascular resistance, helping the heart pump more efficiently and easing strain on the cardiovascular system.
• Helps decrease the risk of hypertension-related complications such as stroke, myocardial infarction, heart failure, and kidney damage when used long term under medical supervision.
• Once‑daily dosing supports better adherence and stable 24‑hour blood pressure control.

Warnings & Contraindications:

• Contraindicated in patients with hypersensitivity to candesartan cilexetil, hydrochlorothiazide, other sulfonamide‑derived drugs, or any component of the formulation.
• Contraindicated during the second and third trimesters of pregnancy; use in the first trimester is not recommended. ARBs can cause injury and even death to the developing fetus. If pregnancy is detected, discontinue immediately and contact your doctor.
• Contraindicated in severe renal impairment, anuria, or severe hepatic impairment, and in patients with refractory hypokalemia, hypercalcemia, or symptomatic hyperuricemia/gout related to thiazides.
• Use with caution in patients with renal artery stenosis, heart failure, volume depletion (e.g., due to high‑dose diuretics, vomiting, or diarrhea), or electrolyte imbalances (low sodium, low potassium, or magnesium).
• Monitor potassium levels carefully, especially when used with potassium‑sparing diuretics, potassium supplements, or other drugs that increase serum potassium, due to risk of hyperkalemia.
• Drug interactions: Diuretics and other antihypertensives may increase the risk of hypotension; lithium levels may increase (risk of lithium toxicity); non‑steroidal anti‑inflammatory drugs (nsaids) may reduce the antihypertensive effect and impact kidney function.
• May cause dizziness or fatigue; avoid driving or operating machinery until you know how the medicine affects you.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding; if you have kidney disease, liver disease, diabetes, gout, heart failure, or are taking other prescription or over‑the‑counter medicines.
• Keep out of reach of children.
• Not intended to diagnose, treat, cure, or prevent any disease outside the approved medical indications.

Side Effects:

• Common side effects may include dizziness, headache, fatigue, upper respiratory tract infections, back pain, or mild gastrointestinal discomfort (nausea, abdominal pain).
• Due to the diuretic component, changes in laboratory values can occur such as decreased sodium or potassium, increased uric acid (which may trigger gout in susceptible individuals), and slight increases in blood glucose or lipids.
• Less common but serious side effects may include severe hypotension (very low blood pressure), kidney function impairment, significant electrolyte disturbances, or allergic reactions (rash, itching, swelling, difficulty breathing).
• Seek immediate medical attention if you experience severe dizziness or fainting, marked decrease in urine output, swelling of the face, lips, tongue, or throat, difficulty breathing, or any other severe or unusual symptoms.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Form: Film‑coated tablet.
• Strength per tablet: candesartan cilexetil 16 mg + hydrochlorothiazide 12.5 mg.
• Pack size: 14 film‑coated tablets (14 f.c. tabs) per pack.
• Intended use: Prescription antihypertensive medicine for adults.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.