Cefaxone Im 500 Mg Vials

Cefaxone Im 500 Mg Vials

Description:

Cefaxone im 500 mg vial is a prescription systemic antibiotic medication containing ceftriaxone, a third-generation cephalosporin, for intramuscular (im) injection. It is used in hospitals and outpatient clinical settings for the treatment of moderate to severe bacterial infections caused by susceptible gram-positive and gram-negative organisms. Cefaxone works by inhibiting bacterial cell wall synthesis, providing broad-spectrum bactericidal activity for serious infections such as meningitis, pneumonia, septicemia, urinary tract infections, and for perioperative prophylaxis. This product is intended for professional use and must be administered by a healthcare provider.

Indications:

• Meningitis caused by susceptible bacteria.
• Septicaemia and bacteraemia (bloodstream infections).
• Typhoid fever and other serious systemic salmonella infections.
• Complicated and uncomplicated urinary tract infections (uti), including pyelonephritis.
• Lower respiratory tract infections, including community-acquired and hospital-acquired pneumonia.
• Pelvic inflammatory disease and other gynecological infections caused by susceptible organisms.
• Sexually transmitted diseases (std) caused by susceptible pathogens (e.g. gonorrhea, where appropriate per guidelines).
• Skin and soft tissue infections, bone and joint infections, and intra-abdominal infections when caused by ceftriaxone-sensitive bacteria.
• Perioperative prophylaxis in surgical procedures to reduce the risk of postoperative infections, as directed by a physician.

Active Ingredients / Key Components:

• Ceftriaxone sodium – 500 mg per vial (equivalent to 500 mg ceftriaxone base) for intramuscular injection.
• Excipients: Specific excipients and stabilizers are not listed on the provided data; full excipient information is unavailable and should be checked on the official package insert.

Dosage & Administration / How to Use:

• Cefaxone im 500 mg vials are for intramuscular injection only and must be prepared and administered by a qualified healthcare professional.
• Adult dosage: The usual dose of ceftriaxone in adults is 1–2 g once daily or divided into two doses, depending on the type and severity of infection. The 500 mg vial may be used as part of the total daily dose according to the physician’s prescription. Exact dosing must follow the doctor’s instructions and official guidelines.
• Paediatric dosage: Dose is weight-based (mg/kg/day) and must be strictly determined by a paediatrician according to age, weight, and infection severity. Do not use in children without medical supervision.
• Reconstitution: The 500 mg powder is reconstituted with an appropriate volume of a suitable diluent (e.g. sterile water for injection or lidocaine solution for im use, as per the approved leaflet). The specific diluent type and volume must follow the manufacturer’s instructions in the package insert.
• Route of administration: Deep intramuscular injection, usually into a large muscle mass (e.g. gluteal muscle). Injection should be given slowly to minimize discomfort.
• Duration of therapy: Treatment duration depends on the type of infection and clinical response, typically 4–14 days or as directed by the treating physician. Therapy should be continued for at least 48–72 hours after the patient becomes afebrile or evidence of bacterial eradication is achieved.
• Do not self-inject or adjust the dose. Always follow the exact dosing schedule and duration prescribed by your doctor.

Clinical Benefits:

• Broad-spectrum bactericidal activity against many gram-positive and gram-negative organisms by inhibiting bacterial cell wall synthesis.
• Effective in serious systemic infections such as meningitis, septicaemia, and pneumonia, helping to control infection and improve clinical outcomes.
• Convenient once-daily dosing in many indications due to prolonged half-life, which can improve adherence in hospital and outpatient settings.
• Useful for perioperative prophylaxis to reduce the risk of postoperative infections in selected surgical procedures.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to ceftriaxone, other cephalosporins, or any component of the formulation. Use with caution in patients with a history of severe hypersensitivity (e.g. anaphylaxis) to penicillins or other beta-lactam antibiotics.
• Serious, potentially fatal hypersensitivity reactions (including anaphylaxis) can occur. Immediate medical attention is required if signs of allergy (rash, itching, swelling, severe dizziness, difficulty breathing) appear.
• Use with caution in patients with severe renal impairment, hepatic impairment, or both; dosage adjustment or monitoring may be required as per physician’s judgment.
• May cause biliary sludge, gallbladder pseudolithiasis, or kidney stones, especially at high doses or in predisposed patients. Monitor for abdominal pain or jaundice.
• Do not mix or administer simultaneously with calcium-containing solutions in neonates due to risk of precipitation. Special precautions apply in infants and children; follow official guidelines.
• Prolonged use may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, appropriate therapy should be instituted.
• May interfere with certain laboratory tests (e.g. Coombs test, urine glucose tests). Inform the laboratory and your doctor that you are receiving ceftriaxone.
• Consult your doctor before use if pregnant or nursing. Ceftriaxone crosses the placenta and is excreted in breast milk; use only if clearly needed and prescribed by a physician.
• Consult your doctor before use if you have kidney disease, liver disease, gallbladder disease, history of gastrointestinal disease (especially colitis), or previous severe allergic reactions to antibiotics.
• Not intended to diagnose, treat, cure, or prevent any disease without a physician’s supervision. This is a prescription-only medicine and must be used under medical guidance.
• Keep out of reach of children. Accidental injection or misuse can cause serious adverse effects.

Side Effects:

• Common side effects: Pain, redness, or swelling at the injection site; mild diarrhoea; nausea; vomiting; headache; or transient changes in liver enzymes or blood counts.
• Less common but important: Rash, itching, fever, oral or vaginal candidiasis (thrush), dizziness, or changes in blood clotting tests.
• Serious side effects (seek immediate medical attention): Severe allergic reactions (anaphylaxis, angioedema, difficulty breathing), severe or persistent diarrhoea (possible Clostridioides difficile-associated diarrhoea), jaundice, severe abdominal pain, unusual bleeding or bruising, seizures, or significant changes in urine output.
• If any unexpected or severe side effects occur, stop treatment and contact your doctor or go to the nearest emergency department.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Protect the dry powder from moisture and excessive heat. After reconstitution, follow the manufacturer’s instructions regarding in-use storage conditions and time limits; use the reconstituted solution within the recommended period and discard any unused portion safely.

Specifications:

• Product type: Prescription systemic antibiotic medicine for intramuscular injection.
• Strength: 500 mg ceftriaxone per vial.
• Form: Sterile powder for solution for injection (im).
• Route of administration: Intramuscular injection by healthcare professionals only.
• Pack size: 1 vial of 500 mg (actual commercial pack configuration may vary; check outer packaging for exact count).

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.