Coloverin Sr 30 Tablets

Coloverin Sr 30 Tablets

Description:

Coloverin Sr 30 Tablets is a prescription oral antispasmodic and anxiolytic medicine commonly used in Egypt for the management of irritable bowel syndrome (IBS) and functional gastrointestinal disorders associated with abdominal cramps, spasm, and anxiety. It combines an intestinal smooth muscle relaxant with a benzodiazepine derivative to help relieve painful bowel spasms, regulate bowel movements, and reduce associated tension and anxiety that may worsen digestive symptoms. Coloverin Sr is designed for sustained release (sr), providing prolonged symptom control throughout the day when taken as directed by a physician.

Indications:

• Management of irritable bowel syndrome (ibs) with abdominal pain, cramps, and bowel habit disturbances (diarrhea, constipation, or alternating patterns).
• Relief of intestinal and colonic smooth muscle spasm in functional bowel disorders.
• Adjunctive treatment of gastrointestinal conditions where anxiety and tension aggravate symptoms.
• Symptomatic relief of abdominal discomfort, bloating, and colicky pain related to spastic colon and other spastic gastrointestinal conditions, as prescribed by a doctor.

Active Ingredients / Key Components:

• Chlordiazepoxide – exact strength per tablet is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.) (benzodiazepine derivative with anxiolytic, sedative, and muscle relaxant properties).
• Mebeverine hydrochloride – exact strength per tablet is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.) (direct-acting smooth muscle antispasmodic acting on the gastrointestinal tract).
• Other excipients: Not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).

Dosage & Administration / How to Use:

• Use only as prescribed by a physician; dosage may vary according to the patient’s condition and response.
• Typical adult regimen for similar mebeverine/chlordiazepoxide combinations is 1 tablet taken 1–3 times daily; however, the exact recommended dose for Coloverin Sr 30 Tablets is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.) and must be confirmed by your doctor.
• Swallow the tablet whole with a sufficient amount of water. Do not crush, chew, or break, as it is a sustained-release (sr) formulation.
• Usually taken before meals to help prevent meal-related abdominal cramps, unless your doctor advises otherwise.
• Do not exceed the prescribed dose or duration. Long-term use of chlordiazepoxide-containing products may lead to dependence; treatment should be regularly reviewed by the physician.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.

Clinical Benefits:

• Helps relieve abdominal cramps and colicky pain by relaxing smooth muscles of the gastrointestinal tract.
• Reduces bowel spasm and discomfort associated with irritable bowel syndrome and functional bowel disorders.
• Provides anxiolytic and sedative effects via chlordiazepoxide, helping to reduce stress and anxiety that may exacerbate digestive symptoms.
• Sustained-release formulation supports more stable symptom control over an extended period with fewer daily doses, improving treatment adherence.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to chlordiazepoxide, mebeverine, benzodiazepines, or any component of the product.
• Contraindicated in patients with severe respiratory insufficiency, severe hepatic impairment, myasthenia gravis, sleep apnea syndrome, or a history of benzodiazepine dependence or abuse, unless strictly supervised by a specialist.
• Use with extreme caution in elderly patients, those with liver or kidney impairment, respiratory disease, depression, history of substance abuse, or other psychiatric disorders.
• May cause drowsiness, dizziness, or impaired concentration. Avoid driving, operating machinery, or performing tasks requiring alertness until you know how the medicine affects you.
• Abrupt discontinuation after prolonged use may lead to withdrawal symptoms (e.g., anxiety, insomnia, irritability, tremors). Dose should be tapered gradually under medical supervision.
• Avoid alcohol and other central nervous system depressants while taking this medicine, as they may enhance sedative effects and increase the risk of serious side effects.
• Consult your doctor before use if pregnant or planning pregnancy. Benzodiazepines may pose risks to the fetus, especially in the first and third trimesters.
• Consult your doctor before use if breastfeeding, as chlordiazepoxide and/or its metabolites may pass into breast milk.
• Inform your doctor about all medicines you are taking, including other sedatives, antidepressants, antipsychotics, opioids, antihistamines, and muscle relaxants, due to potential drug interactions.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include drowsiness, dizziness, fatigue, lightheadedness, mild sedation, dry mouth, nausea, constipation, or headache.
• Less common side effects may include confusion (especially in the elderly), blurred vision, changes in mood, decreased alertness, or gastrointestinal disturbances such as diarrhea or abdominal discomfort.
• Serious side effects (seek immediate medical attention) may include severe allergic reactions (rash, itching, swelling of face or tongue, difficulty breathing), severe drowsiness, respiratory depression, jaundice, marked changes in behavior, suicidal thoughts, or signs of dependence and withdrawal.
• If you experience any unusual or persistent symptoms, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack or container tightly closed. Do not store above the temperature recommended on the package (exact temperature not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.)). Keep out of reach of children.

Specifications:

• Product type: Oral prescription medicine – antispasmodic and anxiolytic.
• Form: Sustained-release tablet.
• Pack size: 30 tablets per pack.
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.