Concor Plus 5 Mg 30 Tablets

Concor Plus 5 Mg 30 Tablets

Description:

Concor Plus 5 mg 30 Tablets is a prescription antihypertensive medicine used for the treatment of high blood pressure. It is a fixed-dose combination containing a beta-blocker (bisoprolol fumarate) and a thiazide diuretic (usually hydrochlorothiazide), designed to provide effective and long-lasting blood pressure control in adults who require combination therapy. By lowering blood pressure, Concor Plus helps reduce the risk of serious cardiovascular events such as stroke, heart attack, and heart failure. This product is intended for use under medical supervision only.

Indications:

• Treatment of essential (primary) hypertension in adults.
• Patients whose blood pressure is not adequately controlled with bisoprolol or a thiazide diuretic alone.
• Long-term management of high blood pressure to help reduce the risk of cardiovascular complications such as stroke, myocardial infarction, and heart failure.
• Control of symptoms related to elevated blood pressure such as headache, dizziness, and palpitations, as part of overall hypertension management.

Active Ingredients / Key Components:

• Bisoprolol fumarate – 5 mg per tablet (beta-1 selective adrenergic blocker).
• Hydrochlorothiazide – exact strength per tablet is not specified in the available product information (thiazide diuretic). The precise hydrochlorothiazide concentration is unavailable.
• Excipients: Other inactive ingredients (tablet core and coating components) are present but not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).

Dosage & Administration / How to Use:

• The usual recommended dose for adults is 1 tablet of Concor Plus 5 mg once daily, or as directed by your physician.
• Take the tablet in the morning, with or without food, at the same time each day to maintain consistent blood levels.
• Swallow the tablet whole with a sufficient amount of water; do not chew, crush, or break the tablet.
• The dose may be adjusted by your doctor based on your blood pressure response and clinical condition. Do not change your dose or stop taking the medicine without medical advice.
• Treatment with beta-blockers such as bisoprolol must not be abruptly discontinued, especially in patients with ischemic heart disease, as this may lead to temporary worsening of the clinical condition (e.g., angina, arrhythmias, or myocardial infarction). Any discontinuation should be gradual under medical supervision.
• If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed tablet.

Clinical Benefits:

• Provides effective blood pressure reduction through dual action: beta-blockade (bisoprolol) and diuretic effect (hydrochlorothiazide).
• Helps reduce the risk of serious cardiovascular events such as stroke, heart attack, and heart failure associated with uncontrolled hypertension.
• Once-daily dosing supports better treatment adherence and stable 24-hour blood pressure control.
• Combination therapy in a single tablet simplifies the regimen for patients previously taking separate tablets of bisoprolol and a thiazide diuretic.

Warnings & Contraindications:

• Contraindicated in patients with hypersensitivity to bisoprolol, hydrochlorothiazide, other sulfonamide-derived drugs, or any component of the product.
• Contraindicated in severe bradycardia, second- or third-degree atrioventricular (AV) block (without pacemaker), sick sinus syndrome, cardiogenic shock, acute heart failure, or decompensated heart failure requiring intravenous inotropic therapy.
• Contraindicated in severe asthma or severe chronic obstructive pulmonary disease (COPD) where beta-blockade may cause bronchospasm.
• Contraindicated in severe peripheral arterial circulatory disorders, untreated pheochromocytoma (unless adequately treated with alpha-blockers), and metabolic acidosis.
• Use with caution in patients with diabetes mellitus, as bisoprolol may mask symptoms of hypoglycemia (such as tachycardia); regular blood glucose monitoring is recommended.
• Use with caution in patients with renal or hepatic impairment, electrolyte disturbances (especially low potassium or sodium), gout, or history of kidney stones due to the diuretic component.
• May interact with other antihypertensives, antiarrhythmics, calcium channel blockers (e.g., verapamil, diltiazem), NSAIDs, lithium, and certain anti-diabetic drugs; inform your doctor about all medicines you are taking.
• Consult your doctor before use if you are pregnant, planning pregnancy, or breastfeeding. Thiazide diuretics and beta-blockers are generally not recommended in pregnancy unless clearly needed.
• May cause dizziness or fatigue; use caution when driving or operating machinery until you know how the medicine affects you.
• Not intended to diagnose, treat, cure, or prevent any disease without appropriate medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include dizziness, headache, fatigue, weakness, cold extremities, slow heart rate (bradycardia), and gastrointestinal disturbances such as nausea, vomiting, abdominal pain, or diarrhea.
• Due to the diuretic component, increased urination, electrolyte imbalances (low potassium, low sodium), muscle cramps, and increased uric acid (which may trigger gout in susceptible individuals) can occur.
• Less common side effects may include sleep disturbances, depression, shortness of breath, hypotension (low blood pressure), skin rash, or photosensitivity.
• Serious side effects requiring immediate medical attention include severe dizziness or fainting, very slow heartbeat, difficulty breathing or wheezing, severe skin reactions, signs of severe electrolyte imbalance (confusion, irregular heartbeat, severe muscle weakness), or signs of allergic reaction (swelling of face, lips, tongue, or throat).
• If you experience any unusual or persistent symptoms, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer carton to protect from light. Do not store above the temperature specified on the package (commonly below 25°c, if stated). Keep container tightly closed and keep out of reach of children. Do not use after the expiry date printed on the pack.

Specifications:

• Product type: Prescription antihypertensive medicine (beta-blocker + thiazide diuretic combination).
• Strength: Bisoprolol fumarate 5 mg per tablet; hydrochlorothiazide strength not specified in available information.
• Form: Film-coated tablets.
• Pack size: 30 tablets per pack.
• Intended use: Adult patients for the treatment and long-term management of high blood pressure under medical supervision.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.