Concor Amlo 5 Mg 30 Tablets

Concor Amlo 5 Mg 30 Tablets

Description:

Concor Amlo 5 mg 30 tablets is a prescription antihypertensive medicine combining a beta-blocker (bisoprolol fumarate) and a calcium channel blocker (amlodipine) in a single tablet. It is used as substitution therapy in adult patients whose blood pressure is already adequately controlled with the same doses of bisoprolol and amlodipine taken as separate tablets. By simplifying treatment into one daily tablet, Concor Amlo helps improve adherence and supports long-term control of high blood pressure, thereby reducing cardiovascular risk when used under medical supervision.

Indications:

• Treatment of essential hypertension (high blood pressure) in adults.
• Substitution therapy in patients adequately controlled with bisoprolol and amlodipine given concurrently at the same dose levels as in this fixed-dose combination but as separate tablets.
• Helps reduce the risk associated with uncontrolled high blood pressure, such as heart disease, stroke, and vascular complications, when used as part of a comprehensive cardiovascular risk management plan prescribed by a physician.

Active Ingredients / Key Components:

• Bisoprolol fumarate – 5 mg (beta-1 selective adrenergic receptor blocker)
• Amlodipine (as amlodipine besilate or equivalent salt) – 5 mg (dihydropyridine calcium channel blocker)
• Excipients: tablet core and coating excipients (full excipient list and exact concentrations , please check the product leaflet or the manufacturer’s official website; please refer to the official package leaflet).

Dosage & Administration / How to Use:

• The recommended dose is one tablet of Concor Amlo 5 mg once daily, or as directed by your physician.
• Intended as substitution therapy only in patients already stabilized on the same doses of bisoprolol and amlodipine taken separately.
• Take the tablet in the morning, with or without food.
• Swallow the tablet whole with a sufficient amount of water; do not chew, crush, or break the tablet.
• Take the medicine at the same time each day to maintain consistent blood levels and optimal blood pressure control.
• Do not abruptly discontinue treatment unless instructed by your doctor, as sudden withdrawal may lead to temporary worsening of your clinical condition (e.g., rebound hypertension, worsening angina in susceptible patients).
• If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to make up for a missed tablet.
• Dosage adjustments, including any changes in strength, must only be done by a healthcare professional based on blood pressure response and clinical status.

Clinical Benefits:

• Provides dual antihypertensive action by combining a beta-blocker and a calcium channel blocker in one tablet for effective blood pressure control.
• Supports long-term cardiovascular protection by helping reduce high blood pressure, a major risk factor for heart attack, stroke, and other vascular complications.
• Improves treatment convenience and adherence by replacing two separate tablets with a single daily fixed-dose combination.
• Helps maintain stable blood pressure throughout the day with once-daily dosing when taken regularly as prescribed.

Warnings & Contraindications:

• Use only under medical supervision. Not suitable for self-medication.
• Contraindicated in patients with known hypersensitivity to bisoprolol, amlodipine, other dihydropyridines, or any component of the formulation.
• Contraindicated in severe hypotension, cardiogenic shock, severe bradycardia, second- or third-degree atrioventricular (AV) block (without a pacemaker), sick sinus syndrome, acute heart failure or decompensated chronic heart failure requiring intravenous inotropic therapy, and severe aortic stenosis (due to amlodipine component).
• Use with caution in patients with heart failure, conduction disturbances, Prinzmetal angina, peripheral arterial disease, diabetes mellitus (may mask signs of hypoglycemia), hyperthyroidism, severe hepatic impairment, or renal impairment.
• May cause dizziness, fatigue, or lightheadedness; avoid driving, operating machinery, or performing tasks requiring alertness until you know how the medicine affects you.
• Alcohol may enhance the blood pressure-lowering effect and increase dizziness; limit or avoid alcohol unless advised otherwise by your doctor.
• Inform your doctor about all other medications you are taking, including other antihypertensives, antiarrhythmics, calcium channel blockers, digitalis glycosides, NSAIDs, antidepressants, and any over-the-counter or herbal products, due to potential drug interactions.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. Use during pregnancy or lactation only if clearly needed and prescribed by a physician.
• Not intended for use in children and adolescents unless specifically prescribed by a specialist (safety and efficacy data in pediatric populations are limited).
• Do not stop taking Concor Amlo suddenly; dose reduction or discontinuation must be gradual and supervised by a physician to avoid rebound effects.
• Consult your doctor before use if you have liver disease, kidney disease, heart rhythm problems, peripheral vascular disease, or diabetes.
• Keep out of reach of children.

Side Effects:

• Common side effects may include headache, dizziness, fatigue, flushing, ankle or leg swelling (peripheral edema), palpitations, slow heart rate (bradycardia), cold extremities, and gastrointestinal discomfort (nausea, abdominal pain).
• Other possible side effects can include sleep disturbances, depression, shortness of breath, muscle cramps, and mild blood pressure drops, especially at treatment initiation or dose changes.
• Serious but less common side effects may include severe hypotension, worsening heart failure, significant bradycardia, AV block, chest pain or worsening angina, allergic reactions (rash, itching, swelling, difficulty breathing), or liver function disturbances.
• Stop taking the medicine and seek immediate medical attention if you experience severe dizziness or fainting, chest pain, difficulty breathing, swelling of the face, lips, tongue, or throat, or any signs of a severe allergic reaction.
• If any side effect persists, worsens, or you notice any other unexpected symptoms, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the pack. Do not store above the temperature indicated on the package insert (specific temperature range is not available in the provided information; refer to the official leaflet).

Specifications:

• Product type: Prescription antihypertensive medicine (fixed-dose combination).
• Strength: Bisoprolol fumarate 5 mg + amlodipine 5 mg per tablet.
• Form: Film-coated tablet.
• Pack size: 30 tablets per pack.
• Intended use: Adult patients requiring substitution therapy for hypertension, as determined by a physician.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.