Coveram 5Mg/10Mg 15Tab

Coveram 5Mg/10Mg 15Tab

Description:

Coveram 5 mg/10 mg 15 tablets is a prescription combination antihypertensive medicine containing amlodipine and perindopril, used for the long-term management of high blood pressure and cardiovascular risk reduction. It combines a calcium channel blocker (amlodipine) with an angiotensin-converting enzyme (ACE) inhibitor (perindopril) in a single daily tablet to improve blood pressure control, protect the heart and blood vessels, and support long-term cardiovascular health. This product is intended for adult patients under the supervision of a healthcare professional.

Indications:

• Treatment of mild to moderate essential hypertension (high blood pressure).
• Management of patients with stable coronary artery disease to reduce cardiovascular risk (such as risk of heart attack or cardiovascular events), especially in those with a history of myocardial infarction or revascularization procedures, as per perindopril indications.
• May be used in patients requiring combination therapy with a calcium channel blocker and an ACE inhibitor for better blood pressure control, as prescribed by a physician.
• Helps relieve and prevent complications related to uncontrolled hypertension such as increased cardiovascular strain and risk of stroke, heart attack, and other vascular events.

Active Ingredients / Key Components:

• Amlodipine – 5 mg per tablet (dihydropyridine calcium channel blocker).
• Perindopril – 10 mg per tablet (angiotensin-converting enzyme (ACE) inhibitor). The exact salt form (e.g. perindopril arginine or erbumine) is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).
• Excipients: Not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.). For a full list of inactive ingredients, refer to the official package leaflet.

Dosage & Administration / How to Use:

• Usual dose: One tablet of Coveram 5 mg/10 mg once daily, or as directed by your physician. Do not exceed the prescribed dose.
• Administration: Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
• Timing: Preferably taken once daily at the same time each morning, with or without food, to maintain consistent blood levels.
• Duration of use: This medicine is usually intended for long-term treatment. Do not stop taking it without consulting your doctor, even if you feel well, as high blood pressure often has no symptoms.
• Missed dose: If you forget a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed tablet.
• Special populations: Dose adjustments may be required in elderly patients, those with kidney or liver impairment, or in patients on other antihypertensive medications. Follow your doctor’s instructions carefully.

Clinical Benefits:

• Provides effective blood pressure reduction by combining two complementary mechanisms: vasodilation via calcium channel blockade (amlodipine) and inhibition of the renin–angiotensin–aldosterone system (perindopril).
• Helps reduce cardiovascular risk in hypertensive patients and those with stable coronary artery disease, supporting long-term heart and vascular protection.
• Improves blood flow by relaxing peripheral and coronary blood vessels, decreasing peripheral vascular resistance and myocardial oxygen demand.
• Once-daily fixed-dose combination improves treatment convenience and may enhance adherence compared to taking separate tablets.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to amlodipine, perindopril, other dihydropyridine calcium channel blockers, other ACE inhibitors, or any component of the product.
• Contraindicated in patients with a history of angioedema associated with previous ACE inhibitor therapy or hereditary/idiopathic angioedema.
• Do not use in pregnancy, especially during the second and third trimesters, as ACE inhibitors can cause serious harm to the fetus. If pregnancy is planned or suspected, consult your doctor immediately.
• Not recommended during breastfeeding unless clearly needed and directed by a physician.
• Use with caution in patients with severe hypotension, aortic stenosis, hypertrophic cardiomyopathy, heart failure, renal artery stenosis, kidney impairment, liver impairment, or electrolyte disturbances (especially hyperkalemia).
• Monitor blood pressure, kidney function, and serum potassium regularly, particularly in elderly patients or those on diuretics, potassium supplements, or potassium-sparing diuretics.
• May cause dizziness or fatigue; use caution when driving or operating machinery until you know how the medicine affects you.
• Consult your doctor before use if you are taking other medications such as diuretics, other antihypertensives, NSAIDs, lithium, potassium supplements, potassium-sparing diuretics, or certain immunosuppressants, as interactions may occur.
• Consult your doctor before use if pregnant, nursing, taking medications, or have medical conditions such as kidney disease, liver disease, heart failure, diabetes, or vascular disease.
• Not intended to diagnose, treat, cure, or prevent any disease outside its approved medical indications.
• Keep out of reach of children.

Side Effects:

• Common side effects may include headache, dizziness, flushing, palpitations, ankle or leg swelling (peripheral edema), fatigue, cough (typical of ACE inhibitors), and gastrointestinal discomfort such as nausea or abdominal pain.
• Less common side effects may include low blood pressure (hypotension), muscle cramps, rash, pruritus, or changes in kidney function or potassium levels.
• Serious but rare side effects include angioedema (swelling of the face, lips, tongue, or throat), severe hypotension, chest pain, irregular heartbeat, or severe allergic reactions. Stop the medicine and seek urgent medical attention if any of these occur.
• If you experience persistent dry cough, marked swelling, difficulty breathing, severe dizziness, fainting, or any unusual symptoms, contact your doctor promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the outer carton to protect from light. Keep container tightly closed and out of reach of children. Do not use after the expiry date stated on the packaging.

Specifications:

• Product type: Prescription antihypertensive medicine (fixed-dose combination).
• Form: Film-coated tablets.
• Strength: Each tablet contains amlodipine 5 mg + perindopril 10 mg.
• Pack size: 15 tablets per pack.
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.