Dapaveldactin 10 Mg

Dapaveldactin 10 Mg

Description:

Dapaveldactin 10 mg 28 f.c. tabs is an oral prescription antidiabetic medicine containing dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It is used as part of comprehensive diabetes care to help control blood glucose levels in adults with type 2 diabetes mellitus, usually in combination with diet and exercise and often alongside other antidiabetic medications such as metformin. By promoting urinary glucose excretion, Dapaveldactin 10 mg supports long-term glycemic control and contributes to overall health and disease prevention in patients at risk of diabetes-related complications.

Indications:

• Type 2 diabetes mellitus in adults, as monotherapy when metformin is inappropriate due to intolerance or contraindication.
• Type 2 diabetes mellitus in adults, as add-on therapy to other glucose-lowering medicines (e.g., metformin, insulin, sulfonylureas) when these do not provide adequate glycemic control alone.
• Helps lower elevated fasting and postprandial blood glucose levels.
• Helps reduce glycated hemoglobin (HbA1c) as part of long-term diabetes management.
• May assist in modest weight reduction and blood pressure improvement in patients with type 2 diabetes (as observed with SGLT2 inhibitors in general).
• Used as part of a comprehensive diabetes care plan including diet, exercise, and regular blood glucose monitoring.

Active Ingredients / Key Components:

• Dapagliflozin – 10 mg per film-coated tablet.
• Other tablet excipients (film-coating agents, fillers, binders, etc.) – exact composition and concentrations , please check the product leaflet or the manufacturer’s official website; please refer to the official package leaflet for the full excipient list.

Dosage & Administration / How to Use:

• Usual adult dose: 10 mg dapagliflozin (one tablet) once daily, or as directed by the prescribing physician.
• Administration: Swallow the film-coated tablet whole with a glass of water. Do not crush, chew, or break the tablet.
• Timing: Can be taken with or without food, preferably at the same time each day to support adherence.
• Use in combination therapy: When used with insulin or insulin secretagogues (e.g., sulfonylureas), a dose reduction of these agents may be required to reduce the risk of hypoglycemia. Follow your doctor’s instructions carefully.
• Renal or hepatic impairment: Dose adjustment or avoidance may be required in patients with moderate to severe renal impairment or significant liver disease. Use only under strict medical supervision in these cases.
• Missed dose: If a dose is missed, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not take a double dose to make up for a missed one.
• Duration of use: Long-term treatment as prescribed. Do not stop taking Dapaveldactin 10 mg without consulting your doctor, as this may worsen blood glucose control.
• Monitoring: Regularly monitor blood glucose and HbA1c as recommended by your healthcare provider. Kidney function, blood pressure, and volume status should also be periodically assessed.

Clinical Benefits:

• Improves glycemic control in adults with type 2 diabetes by reducing renal glucose reabsorption and increasing urinary glucose excretion.
• Helps lower HbA1c levels when used alone or in combination with other antidiabetic medications.
• Promotes heavy glycosuria, which contributes to calorie loss and may support modest weight reduction in many patients.
• May help reduce systolic blood pressure due to mild osmotic diuresis and volume reduction, as seen with SGLT2 inhibitors.
• Supports comprehensive diabetes management, potentially reducing the risk of long-term microvascular and macrovascular complications when combined with lifestyle modifications and other standard treatments.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to dapagliflozin or any of the excipients in the formulation.
• Not indicated for the treatment of type 1 diabetes mellitus or for diabetic ketoacidosis (DKA); may increase the risk of ketoacidosis in susceptible patients.
• Use with caution in patients with impaired renal function; efficacy is reduced in moderate to severe renal impairment and the risk of adverse effects may be increased. Your doctor should assess kidney function before and during treatment.
• Risk of volume depletion: May cause intravascular volume depletion leading to hypotension or dizziness, especially in elderly patients, those on diuretics, or those with low blood pressure. Ensure adequate hydration.
• Increased risk of genital mycotic (fungal) infections and urinary tract infections; maintain good personal hygiene and seek medical advice if symptoms occur.
• Use with caution in patients with a history of recurrent urinary tract infections or genital infections.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding; dapagliflozin is generally not recommended during pregnancy or lactation unless clearly needed and prescribed by a specialist.
• Consult your doctor before use if you have liver disease, kidney disease, low blood pressure, recurrent infections, or are taking diuretics, antihypertensives, insulin, or other antidiabetic medications.
• May increase the risk of diabetic ketoacidosis even with moderately elevated blood glucose; seek urgent medical attention if you develop nausea, vomiting, abdominal pain, excessive thirst, difficulty breathing, confusion, or unusual fatigue.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision; this medicine must be used only under a healthcare professional’s guidance.
• Keep out of reach of children.

Side Effects:

• Common side effects: Increased urination, thirst, genital fungal infections (e.g., vulvovaginal candidiasis, balanitis), urinary tract infections, mild dehydration, and dyslipidemia (slight changes in blood lipids).
• Less common side effects: Dizziness, hypotension (low blood pressure), rash, pruritus (itching), and back pain.
• Serious but rare side effects: Diabetic ketoacidosis (DKA), severe urinary tract infections (e.g., pyelonephritis, urosepsis), severe dehydration, acute kidney injury, and severe hypersensitivity reactions (angioedema, anaphylaxis).
• Seek immediate medical attention if you experience signs of severe infection (fever, chills, flank pain), symptoms of ketoacidosis (nausea, vomiting, abdominal pain, rapid breathing, confusion), signs of allergic reaction (swelling of face, lips, tongue, or throat; difficulty breathing; severe rash), or marked dizziness/fainting.
• If any side effect persists, worsens, or if you notice any other unusual symptoms, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the package. Store at or below the temperature recommended in the official package insert (specific temperature information is not available in the provided data; refer to the product carton or leaflet).

Specifications:

• Form: Film-coated tablets.
• Strength: 10 mg dapagliflozin per tablet.
• Pack size: 28 film-coated tablets per pack.
• Route of administration: Oral.
• Intended users: Adults with type 2 diabetes mellitus, as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.