Depofort B12 1000 Mcg/Ml - 5 Ampoules

Depofort B12 1000 mcg/ml - 5 Ampoules

Description:

Depofort B12 1000 mcg/ml is an injectable vitamin B12 (hydroxocobalamin) preparation from Pharco, supplied in 5 sterile ampoules for intramuscular administration. It is used therapeutically to treat and prevent vitamin B12 deficiency, which can lead to megaloblastic anemia, neurological disturbances, and general fatigue. As a prescription medicine, Depofort B12 supports normal red blood cell formation, nervous system function, and energy metabolism in patients with confirmed or suspected vitamin B12 deficiency or malabsorption.

Indications:

• Treatment of vitamin B12 deficiency due to dietary insufficiency, malabsorption, or increased requirements.
• Megaloblastic anemia caused by vitamin B12 deficiency (e.g., pernicious anemia, post-gastrectomy states, intestinal malabsorption).
• Neurological manifestations associated with vitamin B12 deficiency, such as peripheral neuropathy, paresthesia, and impaired concentration (as part of a physician-supervised regimen).
• Supportive therapy in patients with chronic gastrointestinal diseases that impair vitamin B12 absorption (e.g., inflammatory bowel disease, celiac disease) as directed by a doctor.
• Prophylaxis of vitamin B12 deficiency in patients at risk (e.g., strict vegetarians/vegans, elderly, patients on long-term metformin or acid-suppressing therapy) when injectable therapy is indicated by a physician.

Active Ingredients / Key Components:

• Hydroxocobalamin (vitamin B12) – 1000 mcg (1 mg) per 1 ml ampoule.
• Each pack contains 5 ampoules, each with 1 ml solution for injection.
• Other inactive ingredients/excipients: Not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.) (please refer to the printed package leaflet for full excipient list).

Dosage & Administration / How to Use:

• Depofort B12 1000 mcg/ml is for intramuscular injection only and must be administered by a healthcare professional or under strict medical supervision.
• Typical adult dosing for vitamin B12 deficiency (general guidance – exact regimen must be determined by the physician):
  • Initial treatment phase: frequent injections (e.g., daily or several times per week) until hematologic and clinical response is achieved.
  • Maintenance phase: injections at longer intervals (e.g., every 1–3 months) to maintain adequate vitamin B12 levels, especially in chronic malabsorption or pernicious anemia.
• Dosage in children, elderly patients, pregnant or breastfeeding women must be individualized by the treating doctor.
• Do not self-inject unless properly trained and instructed by a healthcare professional.
• Do not exceed the prescribed dose or change the dosing schedule without consulting your doctor.
• If a dose is missed, contact your healthcare provider for instructions; do not double the next dose.

Clinical Benefits:

• Helps correct and prevent vitamin B12 deficiency, supporting normal red blood cell formation and reducing the risk of megaloblastic anemia.
• Supports healthy nervous system function and may improve neurological symptoms related to B12 deficiency under medical supervision.
• Contributes to normal energy-yielding metabolism, helping reduce fatigue and weakness associated with low vitamin B12 levels.
• Provides a depot (long-acting) injectable form of vitamin B12, useful in patients with poor gastrointestinal absorption or adherence issues with oral therapy.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to hydroxocobalamin, other cobalamins, or any component of the formulation.
• Use with caution in patients with Leber’s hereditary optic neuropathy, as vitamin B12 may precipitate or worsen optic nerve damage in these individuals.
• Inform your doctor if you have kidney disease, liver disease, any blood disorders, or a history of allergic reactions to injectable vitamins.
• Vitamin B12 therapy may mask folate deficiency; your doctor may check and correct folate levels if needed.
• Consult your doctor before use if pregnant or breastfeeding; treatment should be based on clear medical indication and supervised by a healthcare professional.
• Inform your physician about all medicines you are taking, including other vitamins, supplements, and prescription drugs, to avoid interactions or interference with laboratory tests.
• Not intended for self-diagnosis or self-treatment of anemia or fatigue; proper medical evaluation and laboratory testing are essential.
• Keep out of reach of children.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision.

Side Effects:

• Common or mild side effects may include pain, redness, or swelling at the injection site, mild fever, or general discomfort after injection.
• Less common side effects can include headache, dizziness, nausea, vomiting, diarrhea, or skin rash.
• Allergic or hypersensitivity reactions (e.g., itching, hives, facial or tongue swelling, difficulty breathing) are rare but can be serious; seek immediate medical attention if these occur.
• Very high doses may, in rare cases, cause acneiform eruptions or flushing; inform your doctor if you notice unusual skin changes.
• If you experience chest pain, severe dizziness, difficulty breathing, or any severe or persistent side effects, stop further injections and contact your doctor or emergency services immediately.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Protect from excessive heat and moisture. Keep ampoules in the original packaging until use. Do not freeze. Keep container tightly closed and out of reach of children. Do not use after the expiry date printed on the pack, and do not use if the solution is discolored or contains particles.

Specifications:

• Form: Solution for injection (ampoules).
• Strength: 1000 mcg (1 mg) hydroxocobalamin per 1 ml.
• Pack size: 5 ampoules x 1 ml each.
• Route of administration: Intramuscular injection, as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.