Duphalac 667 gm Syrup 200 ml

Duphalac 667 gm Syrup 200 ml

Description:

Duphalac 667 gm/l Syrup 200 ml is a medicinal osmotic laxative containing lactulose, used to treat constipation and certain liver-related conditions. It works by drawing water into the bowel, softening stools and promoting regular bowel movements, and by reducing the absorption of ammonia in patients with hepatic encephalopathy. Manufactured by Abbott Laboratories, Duphalac syrup is suitable for adults, the elderly, and children under medical supervision and is commonly used for safe, effective relief from chronic and occasional constipation.

Indications:

• Treatment of chronic and occasional constipation, including constipation associated with a low-fiber diet, reduced mobility, or post-surgical conditions.
• Regulation of bowel movements in patients with hemorrhoids or after anorectal surgery where soft stools are desirable.
• Management of hepatic encephalopathy (portal-systemic encephalopathy) by helping reduce blood ammonia levels.
• Supportive therapy in patients with chronic liver disease where reduction of intestinal ammonia production is required.
• Relief of hard, dry stools and associated symptoms such as straining, bloating, and discomfort.

Active Ingredients / Key Components:

• Lactulose – 667 mg/ml (667 g/l) syrup (osmotic laxative and ammonia detoxicant)
• Excipients: Other inactive ingredients may be present in the formulation (full excipient list is not available in the provided information; please refer to the package leaflet for complete details).

Dosage & Administration / How to Use:

• Use exactly as directed by your doctor or as stated on the product leaflet. Do not exceed the recommended dose.
• Route of administration: Oral use only.
• Adults and adolescents (constipation): Typical starting dose is often 15–45 ml per day, which may be adjusted by the physician to a maintenance dose (commonly 15–30 ml per day) to achieve 1–2 soft stools daily. Exact dosing should follow medical advice and local product leaflet.
• Children (constipation): Dose must be determined by a pediatrician according to age and body weight. Always follow your doctor’s instructions carefully.
• Hepatic encephalopathy (adults): Higher doses are usually required and divided over the day (for example, multiple doses daily adjusted to produce 2–3 soft stools per day). Dosage and schedule must be prescribed and monitored by a specialist.
• Duphalac syrup may be taken with or without food. If preferred, it can be mixed with water, juice, or milk to improve taste.
• Measure the dose carefully using the measuring cup or device supplied with the product to ensure accurate dosing.
• Swallow the solution directly after measuring. Do not hold it in the mouth for prolonged periods.
• For constipation, it may take 1–2 days of treatment before the laxative effect is seen. Use regularly as directed for best results.
• Do not use for more than a few days without medical advice, especially in children, the elderly, or patients with chronic illness.

Clinical Benefits:

• Provides effective relief from constipation by softening stools and increasing stool frequency.
• Promotes gentle, predictable bowel movements with reduced straining, helping protect sensitive anorectal areas such as hemorrhoids.
• Acts as an osmotic laxative, drawing water into the colon to increase stool volume and stimulate natural peristalsis.
• Helps reduce blood ammonia levels in patients with hepatic encephalopathy by acidifying colonic contents and promoting the conversion of ammonia to non-absorbable ammonium.
• Supports bowel regularity in long-term management of chronic constipation under medical supervision.

Warnings & Contraindications:

• Do not use Duphalac if you are allergic (hypersensitive) to lactulose or any of the other ingredients in the product.
• Contraindicated in patients with galactosemia, intestinal obstruction (ileus), or suspected perforation of the digestive tract, and in patients with digestive tract obstruction not yet resolved.
• Use with caution in patients with diabetes mellitus, as lactulose may contain small amounts of sugars; consult your doctor before use.
• Prolonged use of laxatives without medical supervision may lead to electrolyte imbalance and dependence; always follow your doctor’s instructions.
• If you experience severe abdominal pain, nausea, vomiting, or signs of acute abdomen, stop using the product and seek medical attention immediately.
• Consult your doctor before use if pregnant or breastfeeding. Lactulose is generally considered safe, but medical advice is recommended.
• Consult your doctor before use if you have liver disease, kidney disease, diabetes, or are on a controlled sodium or sugar diet.
• Not intended to diagnose, treat, cure, or prevent any disease beyond its approved medical indications.
• Keep out of reach of children.
• If there is no improvement in constipation after several days of use, or if symptoms worsen, consult a healthcare professional.

Side Effects:

• Common side effects may include flatulence (gas), abdominal discomfort, mild abdominal cramps, and bloating, especially at the beginning of treatment. These often decrease with continued use or dose adjustment.
• At higher doses, diarrhea and loose stools may occur; if this happens, reduce the dose or consult your doctor.
• Prolonged diarrhea may lead to electrolyte disturbances (such as low potassium) and dehydration; seek medical advice if persistent.
• Less common side effects can include nausea or vomiting. If these are severe or persistent, stop use and consult a healthcare professional.
• Seek immediate medical attention if you experience signs of a severe allergic reaction such as rash, itching, swelling of the face, lips, tongue, or throat, or difficulty breathing.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Do not store above the temperature stated on the package (usually below 25 °c, if specified on the label). Do not freeze. Keep out of reach of children. Do not use after the expiry date printed on the bottle and carton. Dispose of unused medicine according to local regulations.

Specifications:

• Product type: Oral osmotic laxative syrup.
• Active ingredient concentration: Lactulose 667 mg/ml (667 g/l).
• Volume: 200 ml bottle.
• Suitable for: Adults, elderly, and children under medical supervision.
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.