Epicophylline Phenobarbitone L Syrup 125 ml

Epicophylline Phenobarbitone L Syrup 125 ml

Description:

Epicophylline Phenobarbitone L Syrup 125 ml is a prescription respiratory medicine combining a bronchodilator (acefylline piperazine) with a barbiturate sedative (phenobarbital). It is formulated to help relieve bronchospasm and improve breathing in conditions such as bronchial asthma, chronic bronchitis, and emphysema, while also providing a mild sedative effect that can reduce anxiety and restlessness associated with breathing difficulty. This oral syrup is produced by EIPICO and is intended for use under medical supervision only.

Indications:

• Adjunctive treatment of bronchial asthma to help relieve bronchospasm and improve airflow (as prescribed by a physician).
• Management of chronic bronchitis with associated cough, wheeze, and difficulty breathing.
• Supportive treatment in emphysema to help ease breathing and reduce chest tightness.
• May be used where a bronchodilator with additional sedative effect is required to reduce agitation related to respiratory distress, only as directed by a doctor.

Active Ingredients / Key Components:

• Acefylline piperazine – exact concentration in mg per 5 ml is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).
• Phenobarbital – exact concentration in mg per 5 ml is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).
• Other excipients: The full list of inactive ingredients (flavoring agents, sweeteners, preservatives, colorants, solvents) is not available in the provided data. Please refer to the package insert for complete composition.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician. Dosage depends on age, body weight, clinical condition, and response to treatment.
• Typical administration: oral use only. Measure the dose carefully using a medical measuring spoon or oral syringe to ensure accuracy.
• May be taken with or without food, unless your doctor advises otherwise. Taking with food may reduce stomach discomfort in sensitive patients.
• Do not exceed the prescribed dose or frequency. Overdose of phenobarbital can cause serious central nervous system depression and respiratory suppression.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Duration of treatment is determined by the doctor according to the underlying respiratory condition and patient response. Do not stop treatment abruptly without medical advice, especially due to the phenobarbital component.
• In children, elderly patients, or those with liver or kidney impairment, strict medical supervision and dose adjustment are required.

Clinical Benefits:

• Helps dilate the bronchial airways, improving airflow and easing breathing in asthma, chronic bronchitis, and emphysema.
• Reduces bronchospasm and chest tightness, which may help decrease episodes of wheezing and shortness of breath.
• Provides a sedative effect that may reduce anxiety, restlessness, and agitation associated with respiratory difficulty (due to phenobarbital).
• May improve overall comfort, sleep quality, and tolerance to respiratory symptoms when used appropriately under medical supervision.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to acefylline piperazine, phenobarbital, other barbiturates, xanthine derivatives, or any component of the formulation.
• Contraindicated in severe respiratory depression, significant liver impairment, porphyria, or a history of barbiturate dependence or abuse.
• Use with extreme caution in patients with liver disease, kidney impairment, respiratory insufficiency, obstructive sleep apnea, cardiovascular disease, or a history of drug or alcohol abuse.
• Phenobarbital may cause drowsiness, dizziness, and impaired concentration. Avoid driving, operating machinery, or performing tasks requiring alertness until you know how the medicine affects you.
• Avoid concomitant use with alcohol or other central nervous system depressants (such as sedatives, hypnotics, some antihistamines, opioids, or anxiolytics) unless specifically approved by your doctor, as this may increase the risk of severe sedation and respiratory depression.
• May interact with many medicines (e.g., anticoagulants, antiepileptics, oral contraceptives, some antibiotics, antifungals, and others). Inform your doctor and pharmacist about all medications and supplements you are taking.
• Use in children, elderly patients, pregnant women, and breastfeeding mothers requires careful medical assessment of risks and benefits.
• Consult your doctor before use if pregnant, nursing, taking other medications, or if you have liver disease, kidney disease, respiratory problems, seizures, depression, or any chronic medical condition.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision. It is a prescription medicine that must be used according to a healthcare provider’s instructions.
• Keep out of reach of children. Accidental ingestion, especially by children, can be dangerous and requires immediate medical attention.

Side Effects:

• Common side effects may include drowsiness, dizziness, fatigue, lightheadedness, headache, or mild gastrointestinal discomfort such as nausea or vomiting.
• Phenobarbital may cause impaired coordination, slowed reaction time, and difficulty concentrating.
• Allergic reactions (rash, itching, swelling, severe dizziness, difficulty breathing) can occur and require immediate medical attention.
• Serious side effects may include severe drowsiness, confusion, difficulty breathing, fainting, severe hypotension, unusual bleeding or bruising, mood changes, or signs of liver problems (yellowing of skin or eyes, dark urine, persistent nausea).
• Long-term use of phenobarbital may lead to tolerance, dependence, or withdrawal symptoms if stopped abruptly. Do not discontinue without medical guidance.
• If you experience any severe or unexpected side effects, or if symptoms worsen or do not improve, contact your doctor promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and heat sources. Keep the bottle tightly closed when not in use. Do not freeze. Keep out of reach of children. Do not use after the expiry date printed on the package, and discard any remaining syrup according to pharmacist instructions.

Specifications:

• Product form: oral syrup.
• Volume: 125 ml per bottle.
• Intended use: prescription bronchodilator and sedative combination for respiratory conditions, under medical supervision.
• Suitable for: adults and children only as directed by a physician; not for self-medication.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.