Epigonal 75 Mg 1 Ampoules

Epigonal 75 Mg 1 Ampoules

Description:

Epigonal 75 mg ampoule is a prescription fertility medication containing human menopausal gonadotrophin (menotropins: follicle stimulating hormone (FSH) + luteinizing hormone (LH)) purified from the urine of postmenopausal women. It is administered by injection and used under specialist supervision to stimulate ovarian follicular growth, induce ovulation, and support gonadal steroid production in women with certain types of infertility who do not have primary ovarian failure. Epigonal is classified as a hormonal medicine and is typically used in assisted reproductive techniques and controlled ovarian stimulation protocols.

Indications:

• Treatment of female infertility due to anovulation or oligo-ovulation (e.g. polycystic ovary syndrome – PCOS) in patients who have not responded to first-line treatments such as clomiphene citrate.
• Controlled ovarian stimulation for assisted reproductive technologies (ART) such as in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and other ART procedures.
• Stimulation of multiple follicular development in women undergoing ovarian stimulation protocols under specialist care.
• Induction of follicular growth and maturation in women with hypogonadotropic hypogonadism when combined with human chorionic gonadotropin (hCG), as directed by a fertility specialist.

Active Ingredients / Key Components:

• Human menopausal gonadotrophin (menotropins: FSH + LH) – 75 iu per ampoule (equivalent to a combination of follicle stimulating hormone and luteinizing hormone). Exact FSH:LH ratio is not specified in the available data.
• Other inactive ingredients/excipients: Not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).

Dosage & Administration / How to Use:

• Epigonal 75 mg ampoule is for parenteral use only and must be administered by subcutaneous or intramuscular injection, exactly as prescribed by a fertility specialist or gynecologist experienced in infertility treatment.
• The dosage regimen is individualized based on the patient’s response, ovarian reserve, and treatment protocol. Initial doses and subsequent adjustments are determined by the physician using ultrasound monitoring and serum estradiol measurements.
• In anovulatory patients, treatment usually starts within the first 7 days of the menstrual cycle, with daily injections until adequate follicular development is achieved, followed by administration of hCG to trigger ovulation, as directed by the physician.
• In ART cycles (e.g. IVF), Epigonal is used as part of controlled ovarian stimulation protocols, often in combination with GnRH agonists or antagonists and followed by hCG or other triggers according to clinic protocol.
• Do not self-inject unless you have been fully trained by your healthcare provider on preparation, reconstitution (if applicable), injection technique, and safe disposal of needles and syringes.
• Do not change the dose, frequency, or duration of treatment without medical advice. If you miss a dose, contact your doctor immediately for instructions; do not double the dose.

Clinical Benefits:

• Stimulates ovarian follicular growth and development in women with inadequate endogenous FSH and LH activity.
• Promotes maturation of ovarian follicles and supports gonadal steroid production, helping to prepare the endometrium for potential implantation.
• Enhances the chances of ovulation and pregnancy in appropriately selected infertile women when used within a controlled treatment plan.
• Enables controlled ovarian stimulation and multiple follicle development in assisted reproductive technologies (IVF/ICSI), improving the number of retrievable oocytes.

Warnings & Contraindications:

• Use only under the supervision of a physician experienced in infertility treatment and assisted reproductive techniques.
• Contraindicated in women with primary ovarian failure, unexplained ovarian enlargement or cysts not due to polycystic ovary syndrome, hormone-dependent tumors of the breast, ovary, uterus, or pituitary/hypothalamus, undiagnosed vaginal bleeding, or tumors of the hypothalamus or pituitary gland.
• Contraindicated in pregnancy and during breastfeeding.
• Risk of ovarian hyperstimulation syndrome (OHSS): Treatment may cause excessive ovarian response. Contact your doctor immediately if you experience severe pelvic pain, rapid weight gain, abdominal swelling, nausea, vomiting, or shortness of breath.
• Increases the risk of multiple pregnancy (twins or more) and ectopic pregnancy, particularly in ART cycles. Careful monitoring is essential.
• Use with caution in women with known risk factors for thromboembolic events (e.g. personal or family history of blood clots, severe obesity, thrombophilia). Inform your doctor of any history of thrombosis, heart disease, or stroke.
• Consult your doctor before use if you have liver disease, kidney disease, uncontrolled thyroid or adrenal disorders, hyperprolactinemia, or other serious medical conditions.
• Not intended to diagnose, treat, cure, or prevent any disease outside its approved indications. Do not use for weight loss, performance enhancement, or any non-medical purpose.
• Keep out of reach of children. Use only the prescribed ampoule and discard any remaining solution safely according to your pharmacist’s instructions.

Side Effects:

• Common side effects may include injection site pain, redness or swelling, headache, abdominal discomfort, bloating, nausea, breast tenderness, and mild mood changes.
• Serious side effects can include ovarian hyperstimulation syndrome (OHSS), severe abdominal pain or swelling, rapid weight gain, shortness of breath, decreased urine output, blood clots (leg pain/swelling, chest pain, sudden shortness of breath), and allergic reactions (rash, itching, swelling of face/lips/tongue, difficulty breathing). Seek immediate medical attention if these occur.
• Visual disturbances, ovarian torsion, and ovarian cyst rupture have been reported with gonadotrophin therapy; report any sudden severe pelvic pain or visual changes to your doctor immediately.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and heat. Specific temperature requirements (e.g. room temperature or refrigerated storage) should follow the product leaflet; if not available, ask your pharmacist. Keep the ampoule in its original packaging until use. Do not use if the solution is discolored, contains particles, or if the ampoule is damaged. Keep out of reach of children.

Specifications:

• Form: Injectable solution in ampoule.
• Strength: 75 iu human menopausal gonadotrophin (FSH + LH) per ampoule.
• Pack size: 1 ampoule per pack.
• Route of administration: Subcutaneous or intramuscular injection, as directed by the physician.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.