Gliflozino 10 mg 6224000866778

Gliflozino 10 mg 6224000866778

Description:

Gliflozino 10 mg (30 film-coated tablets) is an oral antidiabetic prescription medicine containing dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It is used as part of a comprehensive diabetes care plan to help control blood glucose levels in adults with type 2 diabetes mellitus. By blocking SGLT2 in the kidneys, Gliflozino promotes the excretion of excess glucose in the urine, helping reduce blood sugar, improve glycemic control, and support long-term diabetes management when combined with diet and exercise. This product is classified as a medicine for diabetes care and health prevention of diabetes-related complications.

Indications:

• Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
• Can be used as monotherapy in patients with type 2 diabetes who are intolerant to metformin or for whom metformin is contraindicated (as per physician’s judgment).
• Used in combination therapy with other antidiabetic agents (such as metformin, sulfonylureas, DPP-4 inhibitors, or insulin) when additional glycemic control is needed.
• Helps reduce elevated fasting and postprandial blood glucose levels.
• May contribute to modest weight reduction and reduction in systolic blood pressure in patients with type 2 diabetes (as observed with SGLT2 inhibitors in general).
• Supports long-term prevention of diabetes-related complications by improving overall glycemic control when used as directed by a healthcare professional.

Active Ingredients / Key Components:

• Dapagliflozin – 10 mg per film-coated tablet.
• Other tablet excipients (film-coating agents, fillers, binders, etc.) are present but not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.). Exact excipient composition and concentrations are not available.

Dosage & Administration / How to Use:

• Recommended adult dose (typical): 10 mg dapagliflozin (one tablet) once daily, or as prescribed by the treating physician.
• Administration: Swallow the tablet whole with a sufficient amount of water. Do not crush, break, or chew the film-coated tablet.
• With or without food: Gliflozino 10 mg can be taken with or without food at approximately the same time each day.
• Combination therapy: When used with other antidiabetic medications (e.g., insulin or sulfonylureas), the dose of the concomitant medicine may need adjustment to reduce the risk of hypoglycemia. This must be done only under medical supervision.
• Renal or hepatic impairment: Dose initiation or continuation should be carefully evaluated by a physician in patients with impaired kidney or liver function. Use may be restricted or contraindicated in moderate to severe renal impairment. Follow physician guidance strictly.
• Missed dose: If a dose is missed, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not take a double dose to make up for a missed one.
• Duration of use: Long-term treatment as directed by your doctor. Do not stop taking Gliflozino without consulting your healthcare provider, as this may worsen blood glucose control.

Clinical Benefits:

• Helps significantly lower blood glucose levels in adults with type 2 diabetes by increasing urinary glucose excretion through SGLT2 inhibition.
• Contributes to reduction in HbA1c when used alone or in combination with other antidiabetic agents, supporting better long-term glycemic control.
• May assist in modest weight loss due to caloric loss from glycosuria, which can be beneficial in overweight or obese patients with type 2 diabetes.
• Can help reduce systolic blood pressure in some patients, contributing to overall cardiometabolic risk reduction when combined with lifestyle modifications.
• Provides a complementary mechanism of action when added to metformin or other oral antidiabetics, enhancing overall diabetes management.
• Once-daily oral dosing improves convenience and may support better treatment adherence in long-term diabetes care.

Warnings & Contraindications:

• Not for type 1 diabetes or diabetic ketoacidosis (DKA): Gliflozino 10 mg is not indicated for the treatment of type 1 diabetes or for diabetic ketoacidosis and may increase the risk of ketoacidosis in inappropriate use.
• Renal impairment: Use is not recommended or may be contraindicated in patients with moderate to severe renal impairment or end-stage renal disease. Kidney function should be assessed before and periodically during treatment.
• Risk of volume depletion: May increase the risk of dehydration, hypotension, and dizziness, especially in elderly patients, those on diuretics, or those with low blood pressure. Adequate fluid intake is important.
• Genital and urinary tract infections: Increased risk of genital mycotic infections and urinary tract infections due to glycosuria. Patients should maintain good personal hygiene and seek medical advice if symptoms occur.
• Hypoglycemia risk: When combined with insulin or insulin secretagogues (e.g., sulfonylureas), the risk of hypoglycemia may increase. Dose adjustment of the concomitant agent may be necessary.
• Ketoacidosis: Rare but serious cases of diabetic ketoacidosis have been reported with SGLT2 inhibitors, sometimes with only moderately elevated blood glucose. Seek immediate medical attention if symptoms such as nausea, vomiting, abdominal pain, excessive thirst, difficulty breathing, confusion, or unusual fatigue occur.
• Urinary frequency: Increased urination is expected due to the mechanism of action (glycosuria). This is usually mild but should be monitored, especially in patients at risk of dehydration.
• Pregnancy and breastfeeding: Safety in pregnancy and lactation is not well established. Use only if clearly needed and prescribed by a physician after careful risk–benefit assessment.
• Liver disease: Use with caution in patients with hepatic impairment; dose adjustments or alternative therapy may be required as per physician’s evaluation.
• Consult your doctor before use if pregnant, nursing, taking other medications, or if you have medical conditions such as kidney disease, liver disease, low blood pressure, recurrent urinary tract infections, or a history of ketoacidosis.
• Keep out of reach of children.
• This product is a prescription medicine and should be used only under medical supervision.

Side Effects:

• Common side effects: Increased urination, thirst, mild dehydration, genital fungal infections (e.g., vulvovaginal candidiasis, balanitis), urinary tract infections, dysuria, and back pain.
• Less common side effects: Dizziness, hypotension (low blood pressure), increased cholesterol levels, and mild changes in kidney function tests.
• Serious but rare side effects: Diabetic ketoacidosis (DKA), severe urinary tract infections (including pyelonephritis), Fournier’s gangrene (necrotizing fasciitis of the perineum), and severe hypersensitivity reactions.
• Stop using the product and seek immediate medical attention if you experience signs of severe allergic reaction (rash, itching, swelling of face or throat, severe dizziness, difficulty breathing), symptoms of ketoacidosis (nausea, vomiting, abdominal pain, difficulty breathing, confusion, unusual fatigue), or signs of severe infection (fever, chills, flank pain, or severe genital pain/swelling).
• This is not a complete list of side effects. Always consult your doctor or pharmacist for more information and report any unexpected or bothersome symptoms.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer carton to protect from light. Do not store above the temperature stated on the package (typically below 30°c, if specified). Keep container tightly closed and out of reach of children. Do not use after the expiry date printed on the pack.

Specifications:

• Strength: 10 mg dapagliflozin per film-coated tablet.
• Form: Oral film-coated tablet.
• Pack size: 30 film-coated tablets per pack.
• Intended use: Prescription antidiabetic medicine for adults with type 2 diabetes mellitus.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.