Granitryl 2 mg 5 f.c.tabs

Granitryl 2 mg 5 f.c.tabs

Description:

Granitryl 2 mg 5 f.c.tabs is a prescription antiemetic medicine containing granisetron, a selective 5-HT3 receptor antagonist. It is used to prevent and treat nausea and vomiting associated with cytotoxic chemotherapy and radiotherapy. Each film-coated tablet provides systemic control of chemotherapy-induced nausea and vomiting (CINV) and radiation-induced nausea and vomiting (RINV) by blocking serotonin (5-HT3) receptors in the gut and central nervous system. This product is intended for adult use under medical supervision.

Indications:

• Prevention of acute nausea and vomiting associated with cytotoxic chemotherapy.
• Treatment of nausea and vomiting associated with cytotoxic chemotherapy.
• Prevention of nausea and vomiting associated with radiotherapy.
• Management of serotonin-mediated nausea and vomiting where a 5-HT3 antagonist is indicated, as assessed by a physician.

Active Ingredients / Key Components:

• Granisetron – 2 mg per film-coated tablet (selective 5-HT3 receptor antagonist).
• Excipients: Film-coating and tablet core excipients (such as fillers, binders, disintegrants, and colorants) – exact composition and concentrations , please check the product leaflet or the manufacturer’s official website. Please refer to the official package insert for full excipient details.

Dosage & Administration / How to Use:

• Use only as prescribed by your physician and according to the chemotherapy or radiotherapy protocol.
• Adults (typical regimen – may vary by protocol): The usual oral dose for prevention of chemotherapy-induced nausea and vomiting is often 2 mg once daily, taken within 1 hour before the start of chemotherapy. Some regimens may divide the dose (for example, 1 mg twice daily). Your oncologist will determine the exact dose and schedule.
• For radiotherapy-induced nausea and vomiting, dosing is determined by the treating physician based on radiation type and schedule.
• Tablets should be swallowed whole with a sufficient amount of water. Do not crush or chew the film-coated tablets unless your doctor or pharmacist advises otherwise.
• Can generally be taken with or without food, but follow your doctor’s specific instructions.
• Do not exceed the prescribed daily dose.
• If you miss a dose, contact your doctor for instructions. Do not double the dose to make up for a missed one.
• Duration of use depends on the chemotherapy or radiotherapy course and medical assessment; do not stop the medication abruptly without consulting your doctor.

Clinical Benefits:

• Helps prevent and control chemotherapy-induced nausea and vomiting, improving patient comfort and treatment tolerance.
• Reduces radiotherapy-related nausea and vomiting by blocking serotonin (5-HT3) receptors in the gut and brain.
• Supports better adherence to cancer treatment protocols by minimizing distressing gastrointestinal side effects.
• Selective 5-HT3 receptor antagonism offers targeted antiemetic action with no sedative effect, allowing patients to maintain daily activities where medically appropriate.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to granisetron or any of the excipients in the formulation.
• Use with caution in patients with a history of cardiac disorders, including arrhythmias, prolonged QT interval, or those taking other medicines that may prolong QT interval.
• Caution in patients with severe hepatic impairment, as dose adjustment may be required; follow your doctor’s instructions.
• May mask progressive ileus or gastric distension; monitor patients with recent abdominal surgery or signs of bowel obstruction.
• Consult your doctor before use if you are pregnant, planning pregnancy, or breastfeeding. Granisetron should be used during pregnancy or lactation only if clearly needed and prescribed by a physician.
• Inform your doctor about all other medicines you are taking, including antidepressants (SSRIs, SNRIs), antiarrhythmics, antipsychotics, and other serotonergic drugs, due to potential risk of serotonin syndrome or cardiac effects.
• Not intended for self-medication; use only under medical supervision as part of a chemotherapy or radiotherapy regimen.
• Keep out of reach of children.
• Not intended to diagnose, treat, cure, or prevent any disease outside its approved indications.

Side Effects:

• Common side effects: Headache, constipation, diarrhea, abdominal pain, asthenia (weakness), and insomnia may occur. These are usually mild to moderate.
• Less common side effects: Dizziness, rash, pruritus (itching), fever, and changes in liver function tests.
• Serious side effects (seek immediate medical attention): Signs of allergic reaction such as swelling of the face, lips, tongue, or throat; difficulty breathing; severe rash; chest pain; palpitations; or signs of heart rhythm disturbances (e.g., fainting, rapid or irregular heartbeat).
• If you experience severe constipation, persistent abdominal pain, or signs of bowel obstruction, contact your doctor immediately.
• Report any unexpected or bothersome side effects to your physician or pharmacist.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed in its original blister and carton to protect from moisture. Do not store above the temperature stated on the package (typically below 30°c, if specified on the local pack). Keep out of reach of children. Do not use after the expiry date printed on the pack.

Specifications:

• Product type: Prescription antiemetic medicine (selective 5-HT3 receptor antagonist).
• Active ingredient strength: Granisetron 2 mg per film-coated tablet.
• Form: Film-coated tablets (f.c.tabs).
• Pack size: 5 film-coated tablets per pack (suitable for short chemotherapy or radiotherapy courses as prescribed).
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.