Itrin 5 Mg Tablets
Description:
Itrin 5 mg tablets are a prescription oral medicine containing terazosin, an alpha-1 adrenergic receptor blocker used primarily for the treatment of symptomatic benign prostatic hyperplasia (BPH) and mild to moderate hypertension. By selectively blocking alpha-1 receptors in smooth muscle, particularly in the prostate, bladder neck, and blood vessels, Itrin helps relieve urinary symptoms associated with enlarged prostate and lowers elevated blood pressure. It is manufactured by Abbott Laboratories and is commonly prescribed for adult men with BPH and adults with high blood pressure, as part of a comprehensive cardiovascular and urological health management plan.
Indications:
- Treatment of symptomatic benign prostatic hyperplasia (BPH) in adult men, including urinary symptoms such as weak stream, hesitancy, incomplete bladder emptying, frequent urination (especially at night), and urgency.
- Improvement of urinary flow and reduction of BPH-related obstruction by relaxing smooth muscle in the prostate and bladder neck.
- Treatment of mild to moderate essential hypertension in adults, either as monotherapy or in combination with other antihypertensive agents, as directed by a physician.
- Reduction of blood pressure to help lower the risk of cardiovascular complications associated with uncontrolled hypertension, when used as part of an overall treatment plan.
Active Ingredients / Key Components:
- Terazosin – 5 mg per tablet (alpha-1 adrenergic receptor antagonist).
- Excipients/inactive ingredients: Not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.). Refer to the package leaflet for the complete list of excipients.
Dosage & Administration / How to Use:
- Use exactly as prescribed by your physician. Dosage may vary depending on indication (BPH or hypertension), patient age, comorbidities, and response to treatment.
- For BPH (typical adult regimen – for information only; follow your doctor’s instructions):
- Therapy is usually initiated with a low dose once daily at bedtime to reduce the risk of first-dose hypotension (sudden drop in blood pressure).
- The dose may be gradually increased by the physician based on symptom relief and tolerability, up to a maintenance dose that may include 5 mg tablets once daily.
- For hypertension (typical adult regimen – for information only; follow your doctor’s instructions):
- Treatment usually starts with a low dose once daily, often at bedtime, with gradual titration according to blood pressure response.
- Itrin 5 mg tablets may be used as part of the titrated dose schedule or as a maintenance dose as determined by the physician.
- Administration:
- Take the tablet orally with a glass of water.
- May be taken with or without food, but take it consistently in the same way each day.
- To minimize dizziness or fainting, the first dose and dose increases are usually taken at bedtime unless your doctor advises otherwise.
- If you miss a dose: Take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed dose. If therapy is interrupted for several days, contact your doctor, as treatment may need to be restarted at a lower dose.
- Do not stop taking Itrin 5 mg tablets abruptly without consulting your doctor, especially if being used for blood pressure control.
Clinical Benefits:
- Helps relieve lower urinary tract symptoms associated with benign prostatic hyperplasia by relaxing smooth muscle in the prostate and bladder neck.
- Improves urinary flow rate and reduces urinary frequency, urgency, and nocturia (night-time urination), enhancing quality of life in men with BPH.
- Provides effective reduction of mild to moderate high blood pressure by decreasing peripheral vascular resistance through alpha-1 receptor blockade.
- Supports cardiovascular health when used as part of a comprehensive hypertension management plan, potentially helping to reduce long-term complications of uncontrolled blood pressure.
- Once-daily dosing regimen (as directed by the physician) supports better adherence and convenient long-term management of BPH and/or hypertension.
Warnings & Contraindications:
- Contraindicated in patients with known hypersensitivity or allergy to terazosin or any component of the formulation.
- May cause significant postural (orthostatic) hypotension, dizziness, or fainting, especially with the first dose, after dose increases, or when therapy is restarted. Stand up slowly from sitting or lying positions.
- Use with caution in patients with a history of syncope, severe cardiovascular disease, or in those taking other antihypertensive medications, nitrates, or phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil), as additive blood pressure lowering may occur.
- Patients with hepatic or renal impairment should use Itrin 5 mg tablets only under close medical supervision; dose adjustment may be required.
- May affect the ability to drive or operate machinery, particularly at the start of treatment or after dose increases. Avoid such activities if you feel dizzy, lightheaded, or faint.
- Intraoperative Floppy Iris Syndrome (IFIS) has been observed during cataract surgery in some patients treated with alpha-1 blockers. Inform your ophthalmologist if you are taking or have previously taken terazosin before cataract surgery.
- Not recommended for use in children or adolescents, as safety and efficacy in this age group have not been established.
- Pregnancy and breastfeeding: Although primarily indicated for men with BPH, if considered for hypertension in women, use during pregnancy or lactation should only occur if clearly needed and under strict medical supervision. Consult your doctor.
- Consult your doctor before use if you have heart disease, history of stroke, severe liver or kidney disease, or are taking medications such as other blood pressure drugs, diuretics, erectile dysfunction medications, or strong CYP3A4 inhibitors.
- Keep out of reach of children.
Side Effects:
- Common side effects may include dizziness, lightheadedness (especially when standing up), headache, fatigue, drowsiness, nasal congestion, and weakness.
- Some patients may experience palpitations, rapid heartbeat, edema (swelling of ankles or feet), nausea, or gastrointestinal discomfort.
- Less common but potentially serious side effects include severe hypotension, fainting, chest pain, shortness of breath, or pronounced irregular heartbeat. Seek immediate medical attention if these occur.
- Rarely, prolonged or painful erection (priapism) may occur; this is a medical emergency and requires immediate treatment.
- If you experience persistent dizziness, severe weakness, visual disturbances, or any unusual symptoms, contact your doctor promptly.
Storage Instructions:
Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the pack. Store at or below the temperature specified on the package insert (exact temperature range not provided in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.); refer to the product packaging).
Specifications:
- Form: Tablet (oral use).
- Strength: 5 mg terazosin per tablet.
- Pack size: 14 tablets per pack (ITRIN 5 MG 14 TAB).
- Product type: Prescription medicine for benign prostatic hyperplasia and mild to moderate hypertension.
Disclaimer: All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.
