Ketosteril 100 Tablets

Ketosteril 100 Tablets

Description:

Ketosteril 100 Tablets is a prescription medicinal product used in the management of chronic kidney disease (CKD)–related disordered protein metabolism. It contains alpha-ketoanalogues of essential amino acids combined with selected essential amino acids to help prevent and treat complications arising from faulty or deficient protein metabolism in patients with chronic renal insufficiency who are on a low-protein diet. Ketosteril supports nutritional status, helps reduce uremic symptoms, and may slow the progression of kidney damage when used alongside dietary protein restriction and standard nephrology care.

Indications:

• Prevention and therapy of damage due to faulty or deficient protein metabolism in chronic renal insufficiency.
• Use in adult patients with chronic kidney disease and a glomerular filtration rate (GFR) generally below 25 ml/min, in combination with a protein-restricted diet (about 40 g protein per day or less for adults).
• Helps maintain adequate amino acid supply in patients with chronic renal failure while limiting nitrogen intake.
• Supports nutritional status and may help reduce symptoms associated with advanced kidney disease related to protein metabolism disorders.

Active Ingredients / Key Components:

• Alpha-ketoanalogues of essential amino acids (exact per-tablet quantities not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.)):
  • Alpha-ketoanalogue of isoleucine
  • Alpha-ketoanalogue of leucine
  • Alpha-ketoanalogue of phenylalanine
  • Alpha-ketoanalogue of valine
  • Alpha-ketoanalogue of methionine
• Essential amino acids (exact per-tablet quantities not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.)):
  • L-lysine
  • L-threonine
  • L-tryptophan
  • L-histidine
  • L-tyrosine
• Other excipients and coating components: not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).
• Note: The exact mg content of each component per tablet is not provided in the current data and is therefore unavailable.

Dosage & Administration / How to Use:

• Unless otherwise prescribed by the physician, the usual adult dose is 4 to 8 tablets three times daily.
• Tablets should be taken during meals to optimize absorption and metabolic utilization of the ketoanalogues and amino acids.
• Swallow tablets whole with a sufficient amount of water; do not crush or chew unless directed by your doctor.
• Use only under medical supervision, particularly in patients with chronic kidney disease.
• Ketosteril must be used in conjunction with a protein-restricted diet (approximately 40 g protein per day or less in adults, as directed by your nephrologist or dietitian).
• Duration of therapy is long term and depends on the course of chronic renal insufficiency; follow your nephrologist’s recommendations and do not stop treatment without medical advice.

Clinical Benefits:

• Helps prevent and treat damage caused by faulty or deficient protein metabolism in chronic renal insufficiency.
• Provides essential amino acid precursors with minimal nitrogen load, supporting nutritional status in patients on low-protein diets.
• Supports the maintenance of muscle mass and protein balance in chronic kidney disease patients.
• Used as part of a comprehensive renal management plan, it may help reduce uremic symptoms associated with advanced kidney impairment.

Warnings & Contraindications:

• Contraindicated in patients with hypercalcemia (elevated blood calcium levels).
• Contraindicated in patients with disturbed amino acid metabolism.
• In patients with hereditary phenylketonuria, it must be considered that Ketosteril contains phenylalanine.
• Serum calcium levels must be monitored regularly during treatment, as hypercalcemia may develop.
• Use only under the supervision of a physician experienced in the management of chronic kidney disease.
• Consult your doctor before use if you are pregnant, planning pregnancy, or breastfeeding.
• Inform your physician about all other medications, supplements, or vitamins you are taking to avoid interactions.
• Patients with severe liver disease, metabolic disorders, or other serious medical conditions should use this product only after medical evaluation.
• Not intended for use in children unless specifically prescribed by a pediatric nephrologist.
• Keep out of reach of children.

Side Effects:

• The main reported side effect is hypercalcemia (elevated blood calcium levels); regular monitoring of serum calcium is recommended.
• Signs of hypercalcemia may include nausea, vomiting, constipation, abdominal pain, muscle weakness, confusion, or increased thirst and urination; contact your doctor immediately if these occur.
• Other side effects are not commonly reported but may include gastrointestinal discomfort or intolerance in sensitive individuals.
• Seek medical attention if you experience any unusual symptoms, allergic reactions (such as rash, itching, swelling, or difficulty breathing), or severe side effects.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Form: Film-coated tablet.
• Count: 100 tablets per pack.
• Serving size: As prescribed (commonly 4–8 tablets three times daily for adults).
• Intended use: Prescription support in chronic renal insufficiency with protein-restricted diet.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.