Lezberg Plus 12.5/20 Mg 30 Tablets

Lezberg Plus 12.5/20 Mg 30 Tablets

Description:

Lezberg Plus 12.5/20 mg 30 tablets is a prescription antihypertensive medicine used to treat high blood pressure (hypertension) in adults. It combines two active ingredients, olmesartan (an angiotensin II receptor blocker – ARB) and hydrochlorothiazide (a thiazide diuretic), to provide dual blood pressure control. By relaxing blood vessels and increasing the excretion of excess salt and water, Lezberg Plus helps lower and maintain blood pressure, thereby reducing the risk of serious cardiovascular events such as stroke, heart attack, and kidney damage. This product is film‑coated to improve swallowing and gastrointestinal tolerability and is intended for regular, long‑term blood pressure management under medical supervision.

Indications:

• Treatment of essential hypertension (high blood pressure) in adults.
• Management of patients whose blood pressure is not adequately controlled by olmesartan or hydrochlorothiazide alone.
• Helps reduce the risk of complications associated with long‑standing high blood pressure, such as stroke, heart attack, and kidney impairment, when used as part of a comprehensive cardiovascular risk‑reduction plan.
• May be used as a replacement therapy in patients already stabilized on the individual components taken separately at the same doses.

Active Ingredients / Key Components:

• Olmesartan medoxomil – 20 mg per film‑coated tablet (angiotensin II receptor blocker – ARB).
• Hydrochlorothiazide – 12.5 mg per film‑coated tablet (thiazide diuretic).
• Other excipients: Full excipient list (tablet core and film coat) is not available in the provided information. Refer to the official package leaflet for complete inactive ingredients.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician experienced in the management of hypertension.
• Typical adult dose: 1 tablet of Lezberg Plus 12.5/20 mg once daily. The exact dose and duration are determined by your doctor based on your blood pressure response and clinical condition.
• Administration: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
• With or without food: Lezberg Plus can be taken with or without food, but it is preferable to take it at the same time each day to maintain consistent blood levels.
• If a dose is missed: Take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed tablet.
• Do not stop taking Lezberg Plus without consulting your doctor, even if you feel well, as high blood pressure often has no symptoms.
• Patients with kidney or liver impairment, elderly patients, or those on other antihypertensive medicines may require dose adjustment and closer monitoring as directed by a healthcare professional.

Clinical Benefits:

• Provides dual blood pressure control by combining an ARB (olmesartan) with a diuretic (hydrochlorothiazide) for enhanced antihypertensive efficacy.
• Helps relax and widen blood vessels, allowing blood to flow more easily and reducing strain on the heart.
• Promotes excretion of excess salt and water through the kidneys, helping to lower blood volume and blood pressure.
• Supports long‑term protection against hypertension‑related complications such as stroke, heart attack, and progressive kidney damage when used regularly as prescribed.
• Once‑daily dosing improves convenience and may support better treatment adherence in chronic blood pressure management.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to olmesartan, hydrochlorothiazide, other sulfonamide‑derived drugs, or any component of the formulation.
• Contraindicated during pregnancy, especially in the second and third trimesters, due to risk of injury and death to the developing fetus. If pregnancy is detected, stop Lezberg Plus immediately and contact your doctor.
• Contraindicated in severe kidney impairment, anuria (inability to produce urine), or severe liver impairment/cholestasis, unless specifically directed and closely monitored by a specialist.
• Use with caution in patients with renal artery stenosis, heart failure, electrolyte imbalances (such as low sodium, low potassium, or high calcium), gout, diabetes, or a history of severe allergic reactions.
• Hydrochlorothiazide may increase sensitivity to sunlight (photosensitivity). Avoid excessive sun exposure and use adequate sun protection.
• May cause electrolyte disturbances (changes in potassium, sodium, magnesium) and changes in kidney function. Regular monitoring of blood pressure, kidney function, and electrolytes is recommended.
• Inform your doctor about all medicines you are taking, especially other antihypertensives, diuretics, lithium, NSAIDs, corticosteroids, antidiabetic drugs, or potassium‑affecting agents, as interactions may occur.
• Consult your doctor before use if pregnant, planning pregnancy, or nursing. Breastfeeding is generally not recommended while on ARB/thiazide combinations unless clearly needed and supervised.
• May cause dizziness or fatigue, particularly at the start of treatment or when the dose is increased. Use caution when driving or operating machinery until you know how the medicine affects you.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include dizziness, headache, fatigue, weakness, nausea, abdominal discomfort, or increased urination, especially at the beginning of therapy.
• Possible laboratory changes: decreased potassium, sodium, or magnesium; increased uric acid, blood glucose, or changes in kidney function tests and lipids due to the diuretic component.
• Less common but serious side effects may include severe dizziness or fainting, irregular heartbeat, muscle cramps or weakness, significant reduction in urine output, signs of kidney problems, severe abdominal pain, or yellowing of the skin/eyes (jaundice).
• Allergic reactions such as rash, itching, swelling of the face, lips, tongue, or throat, and difficulty breathing require immediate medical attention.
• If you experience persistent, severe, or unusual symptoms, stop taking the medicine and contact your doctor or seek emergency medical care.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Serving size: 1 tablet.
• Count: 30 film‑coated tablets per pack.
• Form: Oral tablet (film‑coated).
• Strength per tablet: olmesartan medoxomil 20 mg + hydrochlorothiazide 12.5 mg.
• Intended use: Prescription antihypertensive medicine for adults.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.