Macrofuran 50 Mg 30 Capsules

Macrofuran 50 Mg 30 Capsules

Description:

Macrofuran 50 mg 30 capsules is a prescription oral antibiotic medicine containing nitrofurantoin, a nitrofuran derivative urinary germicide. It is specifically used for the treatment and prevention of uncomplicated urinary tract infections (UTIs) caused by susceptible bacteria. Macrofuran works locally in the urinary tract by inhibiting bacterial growth and damaging bacterial DNA, helping to clear infection, relieve urinary symptoms such as burning and frequency, and reduce the risk of recurrent UTIs. It is intended for use under medical supervision only.

Indications:

• Treatment of acute uncomplicated urinary tract infections (UTIs), such as cystitis, caused by nitrofurantoin‑sensitive organisms.
• Management of lower urinary tract infections presenting with symptoms like burning during urination, urgency, frequency, and lower abdominal discomfort, as directed by a physician.
• Prevention of recurrent urinary tract infections in selected patients when prescribed by a healthcare professional.

Active Ingredients / Key Components:

• Nitrofurantoin – 50 mg per capsule.
• Other inactive ingredients/excipients: Detailed excipient list is not available in the provided information; please refer to the package leaflet for full composition.

Dosage & Administration / How to Use:

• Macrofuran 50 mg is for oral use only and should be taken exactly as prescribed by your doctor.
• It is generally recommended to take nitrofurantoin with food or milk to improve absorption and reduce stomach upset.
• Swallow the capsule whole with a full glass of water; do not crush or chew.
• Typical adult dosing regimens for uncomplicated UTIs may involve multiple daily doses; the exact dose, frequency, and duration must be determined by the prescribing physician based on age, kidney function, and severity of infection.
• For prophylaxis of recurrent UTIs, a lower daily dose may be used as directed by the doctor.
• Do not skip doses and complete the full course even if symptoms improve early, to reduce the risk of resistance and recurrence.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose; do not double the dose to make up for a missed one.

Clinical Benefits:

• Targets and controls bacterial growth in the urinary tract, helping to clear urinary infections effectively.
• Reduces bothersome UTI symptoms such as burning urination, urgency, frequency, and discomfort.
• Acts as a urinary germicide with localized action in urine, limiting systemic exposure compared to some other antibiotics.
• Can be used, under medical supervision, to help prevent recurrent urinary tract infections in selected patients.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to nitrofurantoin or any component of the formulation.
• Contraindicated in patients with significantly impaired renal function (reduced creatinine clearance), as inadequate urinary levels and increased toxicity may occur.
• Use with caution in patients with liver disease, pulmonary disease, anemia, diabetes, electrolyte imbalance, or vitamin B deficiency, and in those with a history of peripheral neuropathy.
• May cause false results in some laboratory tests (e.g., urinary glucose with Benedict’s reagent, changes in serum glucose, bilirubin, alkaline phosphatase, and urinary creatinine); inform laboratory staff that you are taking nitrofurantoin.
• Drug interactions: anticholinergic drugs may increase nitrofurantoin bioavailability by delaying gastric emptying; probenecid may decrease renal clearance and increase serum levels, raising toxicity risk; magnesium trisilicate may delay or reduce absorption; food increases bioavailability.
• Use in pregnancy and breastfeeding should only be under strict medical advice; inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
• May cause dizziness or drowsiness in some patients; if affected, avoid driving or operating machinery.
• Consult your doctor before use if pregnant, nursing, taking other medications, or if you have kidney disease, liver disease, lung disease, diabetes, anemia, or any chronic medical condition.
• Not intended to diagnose, treat, cure, or prevent any disease without a doctor’s prescription and supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include nausea, vomiting, loss of appetite, abdominal discomfort, and headache.
• Gastrointestinal upset is more likely if taken on an empty stomach; taking with food or milk may help.
• Less common side effects can include dizziness, drowsiness, rash, pruritus, and temporary changes in urine color.
• Serious but rare side effects may include allergic reactions (rash, itching, swelling, severe dizziness, difficulty breathing), liver problems (yellowing of skin or eyes, dark urine, severe fatigue), lung reactions (shortness of breath, cough, chest pain), blood disorders, or peripheral neuropathy (numbness, tingling, weakness in hands or feet).
• Stop the medicine and seek immediate medical attention if you experience signs of severe allergy, breathing difficulty, unexplained cough, chest pain, severe abdominal pain, persistent vomiting, jaundice, unusual bruising or bleeding, or numbness/tingling in extremities.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the package. Do not store in the bathroom or near moisture or heat sources.

Specifications:

• Active ingredient: nitrofurantoin 50 mg per capsule.
• Form: oral hard capsule.
• Pack size: 30 capsules per pack.
• Intended use: prescription antibiotic medicine for urinary tract infections.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.