Marevan 5 Mg 102 Tablets

Marevan 5 Mg 102 Tablets

Description:

Marevan 5 mg 102 tablets is a prescription oral anticoagulant medicine containing warfarin, a vitamin k antagonist used to thin the blood and prevent harmful blood clots. It is commonly prescribed for long-term prevention and treatment of thromboembolic disorders such as deep vein thrombosis, pulmonary embolism, and stroke prevention in patients with atrial fibrillation or mechanical heart valves. Marevan is produced by Glaxo SmithKline and must always be used under strict medical supervision with regular blood monitoring (INR) to ensure safe and effective anticoagulation.

Indications:

• Treatment and prevention of venous thromboembolism, including deep vein thrombosis (DVT).
• Treatment and prevention of pulmonary embolism (PE).
• Prevention of stroke and systemic embolism in patients with atrial fibrillation.
• Prevention of thromboembolic complications in patients with rheumatic heart disease.
• Prevention of thromboembolism in patients with mechanical prosthetic heart valves, as directed by a cardiologist.
• Secondary prevention after transient ischemic attack (TIA) or ischemic stroke of cardioembolic origin, as prescribed by a specialist.

Active Ingredients / Key Components:

• Warfarin sodium – 5 mg per tablet (vitamin k antagonist oral anticoagulant).
• Other excipients: Full list of inactive ingredients is not available in the provided information. Please refer to the printed package leaflet for complete excipient details.

Dosage & Administration / How to Use:

• Marevan must only be taken exactly as prescribed by your doctor. Do not change the dose or stop the medicine without medical advice.
• The usual starting dose and maintenance dose are individualized based on blood test results (INR – international normalized ratio). There is no fixed standard dose; your doctor will adjust the dose to reach the target INR range.
• Tablets are taken orally once daily, preferably at the same time each day, with or without food, with a glass of water.
• If you miss a dose, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not double the dose to make up for a missed tablet.
• Regular blood monitoring (INR) is essential. Attend all scheduled laboratory tests and follow-up appointments so your doctor can adjust the dose safely.
• Maintain a consistent intake of vitamin k–containing foods (such as green leafy vegetables). Sudden large changes in diet, alcohol intake, or use of new medicines or herbal products may affect your INR and bleeding risk.
• Inform all healthcare providers, including dentists and pharmacists, that you are taking warfarin before any procedure, surgery, or when starting or stopping any medicine (including over-the-counter drugs and herbal supplements).
• Do not use this medicine in children unless specifically prescribed and supervised by a pediatric specialist.

Clinical Benefits:

• Helps prevent formation of dangerous blood clots in veins and arteries, reducing the risk of DVT and PE.
• Reduces the risk of stroke and systemic embolism in patients with atrial fibrillation and other high-risk cardiac conditions.
• Provides long-term anticoagulation in patients with mechanical heart valves and rheumatic heart disease, helping prevent valve-related thromboembolic events.
• Supports secondary prevention after thromboembolic events (such as TIA or previous clot), lowering the chance of recurrence when used and monitored correctly.

Warnings & Contraindications:

• Marevan (warfarin) can cause serious and potentially life-threatening bleeding. It must only be used under medical supervision with regular INR monitoring.
• Contraindicated in active major bleeding, severe uncontrolled hypertension, recent major surgery or trauma with high bleeding risk, known bleeding disorders, severe liver disease, and in patients with known hypersensitivity to warfarin or any component of the product.
• Contraindicated during pregnancy, especially in the first trimester and near term, due to risk of fetal harm and bleeding. Use in pregnancy only if clearly directed by a specialist and when benefits outweigh risks. Safer alternatives are usually preferred.
• Use with extreme caution in patients with history of gastrointestinal bleeding, peptic ulcer, recent stroke, intracranial hemorrhage, kidney or liver impairment, or alcohol abuse.
• Many medicines interact with warfarin (including some antibiotics, antifungals, anti-inflammatory drugs, antiplatelets, other anticoagulants, some heart medicines, antidepressants, and herbal products like ginkgo, garlic, ginseng, and St. John’s wort). Always consult your doctor or pharmacist before adding or stopping any medicine or supplement.
• Avoid excessive alcohol consumption, sudden major dietary changes, or crash diets while on warfarin, as these can alter INR and bleeding risk.
• Use with caution in elderly patients who may be more sensitive to anticoagulants and at higher risk of falls and bleeding.
• Consult your doctor before use if pregnant, nursing, taking any medications, or have medical conditions such as liver disease, kidney disease, hypertension, bleeding disorders, peptic ulcer, recent surgery, or history of stroke.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision. This medicine is used as part of a physician-directed treatment plan.
• Keep out of reach of children. Accidental ingestion can cause severe bleeding and requires immediate medical attention.

Side Effects:

• Common side effects: Easy bruising, prolonged bleeding from cuts, nosebleeds, bleeding gums, heavier or prolonged menstrual bleeding, and minor skin bruises or discoloration.
• Serious side effects (seek immediate medical attention): Unusual or severe bleeding (vomiting blood, coughing blood, blood in urine or stool, black or tarry stools), severe headache, dizziness, weakness, difficulty speaking, vision changes, chest pain, shortness of breath, sudden severe back or abdominal pain, or any signs of stroke or internal bleeding.
• Rare but serious: Skin necrosis, purple toe syndrome, allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing). Stop the medicine and seek urgent medical care if these occur.
• Report any unexplained bruising, bleeding, or change in your usual bleeding pattern to your doctor promptly so your dose and INR can be reassessed.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature indicated on the package insert, and protect from excessive heat and moisture.

Specifications:

• Product type: Prescription oral anticoagulant medicine.
• Strength: 5 mg warfarin sodium per tablet.
• Form: Tablet.
• Pack size: 102 tablets per pack.
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.