Maxophage Xr 1000 Mg 30 Tablets

Maxophage Xr 1000 Mg 30 Tablets

Description:

Maxophage XR 1000 mg is an oral extended-release antidiabetic medicine containing metformin hydrochloride, a biguanide used for the management of type 2 diabetes mellitus. It helps control high blood sugar in adults by improving the body’s response to insulin, reducing glucose production in the liver, and decreasing glucose absorption from the intestine. As a once-daily extended-release tablet, Maxophage XR 1000 mg offers convenient, sustained blood glucose control when used as an adjunct to proper diet and regular exercise, with or without other antidiabetic agents, as prescribed by a physician.

Indications:

• Management of type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus) in adults, particularly in overweight or obese patients.
• Used as an adjunct to diet and exercise to improve glycemic control.
• May be used as monotherapy or in combination with other oral antidiabetic medications or insulin, as directed by the treating physician.
• Helps reduce symptoms and complications associated with uncontrolled high blood sugar, such as excessive thirst, frequent urination, fatigue, and long-term microvascular and macrovascular complications (when part of a comprehensive diabetes management plan).

Active Ingredients / Key Components:

• Metformin hydrochloride – 1000 mg per extended-release tablet.

Dosage & Administration / How to Use:

• Maxophage XR 1000 mg is for oral use only and should be swallowed whole with a glass of water. Do not crush, chew, or split the tablets, as this will affect the extended-release properties.
• It is generally recommended to take the tablet once daily with the evening meal or as directed by your physician to reduce gastrointestinal side effects and ensure optimal glucose control.
• Typical adult dosing of metformin begins with a lower dose and is gradually increased at intervals of about 2 weeks, based on blood glucose response and tolerability, up to a maximum daily dose of 3 g of metformin (in divided or extended-release doses). The exact dose and regimen of Maxophage XR 1000 mg must be determined by the prescribing doctor.
• Take the medicine at the same time each day to maintain consistent blood levels and better glycemic control.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed dose.
• Use in children: According to the provided reference, pediatric dosing is not applicable for this specific product; use only in adults unless otherwise explicitly directed by a specialist.

Clinical Benefits:

• Helps lower elevated blood glucose levels in type 2 diabetes without usually causing weight gain and with a low risk of hypoglycemia when used as monotherapy.
• Reduces hepatic gluconeogenesis (glucose production by the liver), leading to improved fasting blood glucose levels.
• Enhances insulin-mediated glucose uptake and utilization in muscle and adipose tissue, improving overall insulin sensitivity.
• Decreases intestinal absorption of glucose and other hexose sugars, contributing to better postprandial (after-meal) glucose control.
• May improve lipid profile in type 2 diabetic patients, including reductions in triglycerides and LDL cholesterol, as part of comprehensive diabetes management.
• Extended-release formulation provides more stable plasma levels of metformin, which may enhance tolerability and convenience with once-daily dosing.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to metformin hydrochloride or any component of the formulation.
• Contraindicated in patients with severe renal impairment or significant reduction in kidney function, due to the increased risk of lactic acidosis. Renal function must be assessed before starting therapy and periodically thereafter.
• Use is contraindicated in acute or chronic conditions associated with tissue hypoxia (e.g., cardiac or respiratory failure, recent myocardial infarction, shock), severe liver disease, or alcoholism, as these conditions increase the risk of lactic acidosis.
• Discontinue temporarily before and for a period after radiologic studies with intravascular iodinated contrast agents, as recommended by your physician, due to potential impact on kidney function.
• Not recommended in cases of severe infection, dehydration, or in patients undergoing major surgery until the condition is stabilized and kidney function is reassessed.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. Your physician will decide whether to continue, adjust, or change your diabetes medication.
• Consult your doctor before use if you have kidney disease, liver disease, heart failure, history of lactic acidosis, chronic alcohol use, or other serious medical conditions.
• Excessive alcohol intake (acute or chronic) increases the risk of lactic acidosis and should be avoided while taking metformin.
• Not intended to diagnose, treat, cure, or prevent any disease on its own; it must be used as part of a comprehensive diabetes management plan under medical supervision.
• Keep out of reach of children. Accidental ingestion by children may cause serious harm and requires immediate medical attention.

Side Effects:

• Common side effects may include gastrointestinal symptoms such as nausea, vomiting, abdominal discomfort, diarrhea, loss of appetite, or a metallic taste in the mouth. These are often transient and may improve when the dose is taken with food or after dose adjustment.
• Less common effects may include headache, weakness, or mild skin reactions (e.g., rash). Inform your doctor if any side effect is persistent or bothersome.
• Long-term use of metformin may be associated with decreased vitamin B12 absorption, which can lead to vitamin B12 deficiency in some patients. Periodic monitoring of vitamin B12 levels may be advised in long-term therapy.
• A rare but serious adverse effect is lactic acidosis, a medical emergency characterized by symptoms such as rapid breathing, severe fatigue, muscle pain, abdominal pain, feeling cold, dizziness, or slow/irregular heartbeat. If you experience these symptoms, stop the medicine and seek immediate medical attention.
• If you develop signs of severe infection, dehydration, or sudden worsening of kidney function, contact your doctor promptly, as dose adjustment or discontinuation may be necessary.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Active ingredient: metformin hydrochloride 1000 mg per extended-release tablet.
• Form: extended-release tablet for oral use.
• Pack size: 30 tablets per pack.
• Intended use: prescription antidiabetic medicine for adults with type 2 diabetes mellitus, as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.