NEVILOB Amlo 5/5 MG 30 TABLET

NEVILOB Amlo 5/5 MG 30 TABLET

Description:

NEVILOB Amlo 5/5 mg 30 tablet is a prescription cardiovascular medicine combining nebivolol and amlodipine in a single oral tablet. It is used for the treatment of high blood pressure (essential hypertension) and chronic stable angina, helping to control blood pressure, reduce heart workload, and improve blood flow to the heart. This fixed-dose combination is manufactured by Marcyrl Pharmaceutical Industries (MPI) and is intended for adult patients under medical supervision.

Indications:

• Treatment of essential hypertension (high blood pressure) in adults.
• Management of chronic stable angina (chest pain due to reduced blood flow to the heart).
• Helps reduce the risk of cardiovascular complications associated with uncontrolled hypertension, such as heart attack and stroke, when used as part of a comprehensive treatment plan.
• Indicated in patients who require combination therapy with both a beta-blocker (nebivolol) and a calcium channel blocker (amlodipine), or in those already stabilized on these agents given separately at equivalent doses.

Active Ingredients / Key Components:

• Nebivolol – 5 mg per tablet (beta-1 selective adrenergic blocker with vasodilating properties).
• Amlodipine (as amlodipine besylate or equivalent salt) – 5 mg per tablet (dihydropyridine calcium channel blocker).
• Excipients: The full list of inactive ingredients (excipients, binders, fillers, coloring agents, preservatives) is not available in the provided information. Please refer to the official package leaflet for the complete excipient list.

Dosage & Administration / How to Use:

• Dosage must be individualized by the prescribing physician based on the patient’s clinical condition, blood pressure response, and tolerance.
• Typical adult dose: 1 tablet once daily, preferably taken at the same time each day. The exact dose and duration are determined by your doctor.
• Route of administration: Oral. Swallow the tablet whole with a sufficient amount of water; do not crush or chew unless your doctor or pharmacist advises otherwise.
• May be taken with or without food; however, take it consistently in the same way (always with food or always without food) as advised by your physician.
• If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed tablet.
• Do not stop taking NEVILOB Amlo 5/5 mg suddenly without consulting your doctor, as abrupt discontinuation may worsen angina, blood pressure control, or heart condition.
• Use in elderly patients or those with renal/hepatic impairment may require dose adjustment and closer monitoring, as directed by the physician.

Clinical Benefits:

• Helps lower and control high blood pressure, supporting long-term cardiovascular health.
• Combines nebivolol and amlodipine in one tablet, simplifying treatment and improving adherence for patients who need both medications.
• Reduces frequency and severity of angina attacks by improving blood flow to the heart muscle and decreasing oxygen demand.
• Nebivolol’s beta-1 selectivity and vasodilatory effect may provide effective blood pressure control with a favorable tolerability profile in many patients.
• Amlodipine’s long-acting calcium channel blocking action provides sustained 24-hour blood pressure control and anti-anginal effect.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to nebivolol, amlodipine, other beta-blockers, other dihydropyridine calcium channel blockers, or any component of the formulation.
• Contraindicated in patients with severe bradycardia, cardiogenic shock, second- or third-degree atrioventricular (AV) block (without a pacemaker), sick sinus syndrome, or severe heart failure decompensation, unless specifically advised by a cardiologist.
• Use with caution in patients with heart failure, conduction disturbances, peripheral vascular disease, severe hypotension, or a history of myocardial infarction.
• Use with caution in patients with hepatic impairment or renal impairment; dose adjustment and close monitoring may be required.
• May mask symptoms of hypoglycemia in diabetic patients; monitor blood glucose regularly if you have diabetes.
• May interact with other antihypertensives, antiarrhythmics, calcium channel blockers, CYP3A4 inhibitors/inducers, and certain antidepressants. Inform your doctor about all medications and supplements you are taking.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. The safety of nebivolol and amlodipine combination in pregnancy and lactation requires medical evaluation.
• May cause dizziness, fatigue, or light-headedness, especially at the start of treatment or when the dose is increased. Avoid driving or operating machinery until you know how the medicine affects you.
• Alcohol may enhance the blood pressure-lowering effect and increase dizziness; limit or avoid alcohol consumption while taking this medicine.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision. Use only as prescribed by a qualified healthcare professional.
• Keep out of reach of children.

Side Effects:

• Common side effects may include headache, dizziness, fatigue, flushing, palpitations, peripheral edema (swelling of ankles or feet), nausea, abdominal discomfort, or constipation.
• Less common side effects can include slow heart rate (bradycardia), low blood pressure (hypotension), shortness of breath, sleep disturbances, rash, or muscle cramps.
• Serious side effects (seek immediate medical attention) may include severe dizziness or fainting, marked swelling of legs or sudden weight gain, worsening chest pain or new-onset chest pain, irregular heartbeat, severe shortness of breath, or signs of allergic reaction such as facial swelling, difficulty breathing, or severe skin rash.
• Not all possible side effects are listed. If you experience any unusual or persistent symptoms, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the package. Do not store above the temperature specified on the outer packaging (exact temperature range is not available in the provided information; refer to the product leaflet).

Specifications:

• Product type: Prescription cardiovascular medicine for hypertension and chronic stable angina.
• Strength: Nebivolol 5 mg + amlodipine 5 mg per tablet.
• Form: Tablet.
• Pack size: 30 tablets per pack.
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.