Doliprane 1000 Mg 15 Tablets

Doliprane 1000 Mg 15 Tablets

Description:

Doliprane 1000 mg is a branded oral analgesic and antipyretic medicine containing high‑strength paracetamol (acetaminophen). It is used for the relief of moderate pain and the reduction of fever in adults and adolescents, particularly when a 1000 mg dose of paracetamol is clinically indicated. Each tablet delivers a precise dose of paracetamol to help manage headaches, toothache, musculoskeletal pain, menstrual pain, flu‑like symptoms, and other painful conditions while effectively lowering elevated body temperature. Manufactured by Sanofi, Doliprane is widely trusted for its efficacy and safety when used at the recommended dose.

Indications:

• Symptomatic treatment of mild to moderate pain (e.g. headache, toothache, muscle pain, joint pain, back pain).
• Relief of pain associated with colds and flu‑like conditions.
• Reduction of fever (antipyretic) in infectious and inflammatory conditions.
• Adjunctive relief of pain in conditions such as migraine attacks (as directed by a physician).
• Suitable for adults and adolescents who require a 1000 mg dose of paracetamol per intake, according to medical advice.

Active Ingredients / Key Components:

• Paracetamol (Acetaminophen) – 1000 mg per tablet.
• Inactive ingredients/excipients: Exact excipient list (e.g. fillers, binders, coating agents) is not available in the provided information. Please refer to the product package insert for full composition.

Dosage & Administration / How to Use:

• Route of administration: Oral use only.
• Adults: Commonly 500–1000 mg paracetamol per dose, with at least 4–6 hours between doses. Do not exceed a total daily dose of 4000 mg (4 g) of paracetamol from all sources, unless otherwise directed by a physician. Follow your doctor’s or pharmacist’s instructions and the package leaflet.
• Adolescents (body weight usually ≥ 50 kg): Dose and frequency should be determined by a healthcare professional. Maximum daily dose must be adjusted to body weight and must not exceed the recommended total daily dose of paracetamol.
• Swallowing: Swallow the tablet whole with a sufficient amount of water. It may be taken with or without food. In patients with sensitive stomach, taking it with food or after meals may be preferable.
• Duration of use: Do not use for more than 3 days for fever or 5 days for pain without medical advice. If symptoms persist, worsen, or new symptoms appear, consult a doctor.
• Hepatic or renal impairment: Dose interval and maximum daily dose must be reduced according to medical advice. Use only under strict medical supervision in patients with liver or kidney disease.
• Concomitant products: Do not take with other medicines containing paracetamol to avoid overdose.

Clinical Benefits:

• Provides effective relief of mild to moderate pain, helping improve daily comfort and functionality.
• Reduces fever by acting on the thermoregulatory center in the hypothalamus, helping restore normal body temperature.
• Has minimal peripheral anti‑inflammatory effect, which may be preferable for patients who cannot tolerate non‑steroidal anti‑inflammatory drugs (NSAIDs).
• Rapid onset of analgesic and antipyretic action when taken at the recommended dose, supporting quick symptom control in headaches, flu‑like symptoms, and other painful conditions.

Warnings & Contraindications:

• Do not use Doliprane 1000 mg if you are allergic (hypersensitive) to paracetamol or any of the other components of the product.
• Contraindicated in severe liver impairment, active severe hepatic disease, or in cases of severe alcohol abuse due to increased risk of hepatotoxicity.
• Use with extreme caution in patients with liver disease, chronic alcoholism, malnutrition, dehydration, or severe kidney impairment. Dose adjustment and medical supervision are required.
• Do not exceed the recommended dose. Accidental or intentional overdose of paracetamol can cause serious, potentially fatal liver damage.
• Avoid concomitant use with other paracetamol‑containing products, including cold and flu remedies, to prevent cumulative overdose.
• Caution when used with medicines that affect liver enzymes or paracetamol metabolism (e.g. certain antiepileptics, rifampicin) and with chronic excessive alcohol intake, as these may increase the risk of liver toxicity.
• Drug interactions noted for paracetamol include: cholestyramine (may reduce absorption), activated charcoal (may reduce absorption if given soon after ingestion), domperidone and metoclopramide (may enhance absorption).
• Consult your doctor before use if pregnant or breastfeeding. Paracetamol is generally considered compatible when used at recommended doses, but medical advice is recommended.
• Consult your doctor before use if you have liver disease, kidney disease, chronic alcohol use, glucose‑6‑phosphate dehydrogenase (G6PD) deficiency, or are taking other regular medications.
• If high fever persists for more than 3 days, or pain lasts more than 5 days, or if symptoms worsen, seek medical advice.
• Keep out of reach of children.

Side Effects:

• Common side effects are generally rare at recommended doses but may include mild gastrointestinal disturbances such as nausea, stomach discomfort, or vomiting.
• Allergic reactions (hypersensitivity) may occur, including skin rash, itching, urticaria, facial or throat swelling, or difficulty breathing. Stop use and seek immediate medical attention if any signs of allergy appear.
• Serious skin reactions such as Stevens–Johnson syndrome, toxic epidermal necrolysis, or acute generalized exanthematous pustulosis have been reported very rarely with paracetamol. Discontinue immediately and consult a doctor if skin redness, blistering, or peeling occurs.
• High doses or prolonged use, especially above the recommended maximum daily dose, can cause severe liver damage (hepatotoxicity), which may be life‑threatening. Symptoms of overdose may include nausea, vomiting, loss of appetite, sweating, abdominal pain, and later signs of liver failure. Immediate medical attention is essential in suspected overdose, even if you feel well.
• Very rare blood disorders (e.g. thrombocytopenia, leukopenia) have been reported with paracetamol. Seek medical advice if you notice unusual bruising, bleeding, or infections.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the packaging. Store at or below the temperature indicated on the package insert if specified.

Specifications:

• Product type: Oral analgesic and antipyretic medicine.
• Active ingredient: Paracetamol (acetaminophen) 1000 mg per tablet.
• Form: Tablet.
• Pack size: 15 tablets per pack.
• Intended users: Adults and adolescents as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.