One Alpha 0.25 Mcg Tablets

One Alpha 0.25 Mcg Tablets

Description:

One Alpha 0.25 mcg is a prescription medicine containing alfacalcidol, an active vitamin D analogue used to manage disorders of calcium and phosphate metabolism. It is commonly prescribed in chronic kidney disease, hypoparathyroidism, and various bone diseases to help normalize calcium levels, improve bone mineralization, and reduce symptoms related to vitamin D deficiency and impaired bone health. This product is intended for adult and pediatric patients as directed by a physician and should be used under strict medical supervision.

Indications:

• Treatment and prevention of hypocalcaemia (low blood calcium levels).
• Management of hypoparathyroidism (underactive parathyroid glands) associated with disturbed calcium and phosphate balance.
• Treatment of hypophosphataemia (low blood phosphate levels) related to vitamin D metabolism disorders.
• Management of renal osteodystrophy (bone disease associated with chronic kidney failure).
• Treatment of osteomalacia (softening of the bones due to vitamin D deficiency or impaired activation).
• Supportive therapy in chronic kidney disease patients to improve bone health and mineral balance, as prescribed by a nephrologist.

Active Ingredients / Key Components:

• Alfacalcidol – 0.25 mcg per tablet.
• Other excipients: Full excipient list is not available in the provided information; please refer to the official package insert for complete details.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician experienced in managing calcium and bone metabolism disorders.
• Adults (oral): Typical recommended starting dose of alfacalcidol is 1 mcg/day, with maintenance doses usually ranging from 0.25–1 mcg/day, adjusted according to blood calcium, phosphate, and parathyroid hormone levels. Since this product contains 0.25 mcg per tablet, the exact number of tablets per day must be determined by the doctor.
• Pediatric use: Dose and duration must be individualized by a pediatric specialist based on age, weight, and laboratory results.
• Tablets are usually taken by mouth, once daily, with or without food, at the same time each day, unless otherwise directed by your doctor.
• Regular monitoring of serum calcium, phosphate, alkaline phosphatase, and renal function is essential during therapy to avoid hypercalcaemia and other complications.
• Do not change the dose, stop, or restart treatment without consulting your healthcare provider.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed dose.

Clinical Benefits:

• Helps correct low calcium levels in the blood by enhancing intestinal absorption and mobilization of calcium.
• Supports proper bone mineralization, helping to reduce bone pain, muscle weakness, and risk of fractures associated with osteomalacia and renal osteodystrophy.
• Assists in managing mineral and bone disorders in chronic kidney disease by bypassing impaired vitamin D activation in the kidneys.
• Improves symptoms related to hypoparathyroidism by stabilizing calcium and phosphate balance.
• Contributes to overall skeletal health and function when used as part of a comprehensive treatment plan including diet, phosphate binders, and other medications as prescribed.

Warnings & Contraindications:

• Contraindicated in patients with hypercalcaemia (high blood calcium), hypervitaminosis D, or known hypersensitivity to alfacalcidol or any of the excipients.
• Use with extreme caution in patients with renal impairment, nephrolithiasis (kidney stones), arteriosclerosis, or sarcoidosis, and in those receiving digitalis (cardiac glycosides), as hypercalcaemia may increase the risk of toxicity.
• Frequent monitoring of serum calcium, phosphate, and renal function is mandatory; dose adjustments or temporary discontinuation may be required if hypercalcaemia or hyperphosphataemia occurs.
• Avoid excessive intake of calcium supplements or other vitamin D products unless specifically advised by your doctor, as this may increase the risk of hypercalcaemia.
• Consult your doctor before use if pregnant or nursing; use during pregnancy and lactation only if the potential benefit justifies the potential risk to the mother and baby.
• Inform your doctor about all medicines you are taking, including thiazide diuretics, anticonvulsants, digitalis, magnesium-containing antacids, and other vitamin D analogues, due to potential interactions.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision; it is a prescription medicine that must be used under a doctor’s guidance.
• Keep out of reach of children.

Side Effects:

• The most important potential side effect is hypercalcaemia (high blood calcium), which may present with nausea, vomiting, constipation, abdominal pain, loss of appetite, excessive thirst, frequent urination, muscle weakness, confusion, or fatigue.
• Other possible side effects include hyperphosphataemia, pruritus (itching), skin rash, headache, and mild gastrointestinal disturbances.
• Prolonged hypercalcaemia may lead to calcification of soft tissues, kidney stones, and worsening kidney function.
• Seek immediate medical attention if you experience severe or persistent symptoms such as severe abdominal pain, confusion, irregular heartbeat, or signs of allergic reaction (rash, swelling of face or throat, difficulty breathing).

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature specified on the package insert (exact temperature range not available in the provided information).

Specifications:

• Form: Tablets for oral use.
• Strength: 0.25 mcg alfacalcidol per tablet.
• Pack size: 30 tablets per pack (based on reference product information).
• Intended use: Prescription medicine for disorders of calcium and bone metabolism under medical supervision.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.