One Alpha 1 Mgc Tablets

One Alpha 1 Mgc Tablets

Description:

One Alpha 1 mcg capsules (often referred to as One Alpha 1 mcg tablets) is a prescription vitamin D analogue medicine containing alfacalcidol, an active metabolite of vitamin D. It is used to manage and prevent disorders related to calcium and phosphate imbalance, particularly in patients with kidney disease or impaired vitamin D activation. By helping regulate calcium and phosphate levels, One Alpha supports healthy bones, teeth, and proper mineral metabolism. This product is classified as a medicine and should be used only under medical supervision.

Indications:

• Treatment and prevention of hypocalcaemia (low blood calcium levels)
• Management of hypoparathyroidism (reduced parathyroid hormone activity) associated with calcium and phosphate imbalance
• Treatment of hypophosphataemia (low blood phosphate levels), particularly of renal origin
• Renal osteodystrophy associated with chronic kidney disease and dialysis
• Osteomalacia (softening of the bones) due to vitamin D deficiency or impaired vitamin D activation
• Conditions where active vitamin D supplementation is required to normalize calcium and phosphate homeostasis, as determined by a physician

Active Ingredients / Key Components:

• Alfacalcidol – 1 mcg per capsule
• Other inactive ingredients (excipients) are present to form the capsule, but detailed excipient list is not available in the provided information.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician experienced in managing calcium and phosphate metabolism disorders.
• Adults (oral): Recommended starting dose is typically 1 mcg/day, adjusted by the doctor according to blood calcium, phosphate, and alkaline phosphatase levels.
• Maintenance dose (oral): Usually 0.25–1 mcg/day, individualized based on clinical response and laboratory results.
• Adults on dialysis (intravenous use): Initial dose is commonly 1 mcg per dialysis session, two to three times per week. Intravenous use is performed only in a clinical setting by healthcare professionals.
• Capsules are usually taken once daily, preferably at the same time each day, with or without food, as directed by your doctor.
• Regular monitoring of serum calcium, phosphate, and renal function is essential; the doctor may adjust the dose or temporarily stop treatment if hypercalcaemia occurs.
• Do not exceed the prescribed dose and do not stop treatment abruptly without consulting your doctor.

Clinical Benefits:

• Helps correct and maintain normal blood calcium levels in patients with hypocalcaemia.
• Supports healthy bone mineralization and reduces the risk of bone pain and deformities associated with osteomalacia and renal osteodystrophy.
• Improves calcium and phosphate balance in patients with chronic kidney disease and impaired vitamin D activation.
• May help reduce symptoms such as muscle cramps, bone pain, and weakness related to calcium and vitamin D deficiency states.

Warnings & Contraindications:

• Contraindicated in patients with hypercalcaemia (high blood calcium), vitamin D toxicity, or known hypersensitivity to alfacalcidol or any component of the product.
• Use with extreme caution in patients with renal impairment, nephrolithiasis (kidney stones), arteriosclerosis, or sarcoidosis, as they are at higher risk of hypercalcaemia.
• Frequent monitoring of serum calcium, phosphate, and renal function is mandatory during therapy. Dose adjustments or temporary discontinuation may be required if levels become abnormal.
• Avoid concurrent excessive intake of calcium supplements or other vitamin D products unless specifically directed by your doctor, as this may increase the risk of hypercalcaemia.
• Consult your doctor before use if pregnant or nursing; safety in pregnancy and lactation requires careful medical assessment and monitoring.
• Consult your doctor before use if you are taking other medications such as thiazide diuretics, digitalis glycosides, magnesium-containing antacids, or other vitamin D analogues, as interactions may increase the risk of toxicity.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision; it is a prescription medicine and must be used according to a doctor’s instructions.
• Keep out of reach of children.

Side Effects:

• The most significant potential side effect is hypercalcaemia (high blood calcium), which may present with nausea, vomiting, constipation, loss of appetite, excessive thirst, frequent urination, headache, drowsiness, or muscle weakness.
• Other possible side effects may include hyperphosphataemia, pruritus (itching), rash, abdominal pain, or fatigue.
• Prolonged hypercalcaemia can lead to vascular and soft tissue calcification, kidney stones, and kidney damage.
• Seek immediate medical attention if you experience severe or persistent symptoms such as severe abdominal pain, confusion, irregular heartbeat, or signs of allergic reaction (swelling of face, lips, tongue, or difficulty breathing).

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature specified on the package insert (exact temperature range is not available in the provided information).

Specifications:

• Active ingredient: alfacalcidol 1 mcg per capsule
• Form: oral capsule (often referred to as tablet in common usage)
• Pack size: 30 capsules per pack
• Intended use: prescription vitamin D analogue for calcium and bone metabolism disorders

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.