Plendil 10 Mg 30 Tablets

Plendil 10 Mg 30 Tablets

Description:

Plendil 10 mg 30 tablets is a prescription antihypertensive medicine containing felodipine, a long-acting dihydropyridine calcium channel blocker. It is used for the long-term management of high blood pressure and certain types of chronic stable angina by relaxing and dilating blood vessels, improving blood flow, and reducing the workload on the heart. This prolonged-release, film-coated tablet provides sustained 24-hour blood pressure control with once-daily dosing, supporting cardiovascular health and helping reduce the risk of complications associated with uncontrolled hypertension such as stroke, heart attack, and kidney damage.

Indications:

• Treatment of essential (primary) hypertension in adults
• Long-term management of high blood pressure to help reduce cardiovascular risk (e.g., stroke, myocardial infarction, heart failure)
• May be used as monotherapy or in combination with other antihypertensive agents (such as ACE inhibitors, ARBs, diuretics, or beta-blockers) as prescribed by a physician
• Management of chronic stable angina pectoris (as per physician’s recommendation), by improving coronary blood flow and reducing myocardial oxygen demand
• Relief of symptoms related to elevated blood pressure such as headache, dizziness, and palpitations when due to hypertension (under medical supervision)

Active Ingredients / Key Components:

• Felodipine – 10 mg per prolonged-release film-coated tablet
• Excipients: The full list of inactive ingredients (tablet core and film coating components such as fillers, binders, colorants, and coating agents) is not available in the provided information. Please refer to the package leaflet for the complete excipient list.

Dosage & Administration / How to Use:

• Usual adult dose: As prescribed by the physician. For hypertension, felodipine is commonly started at a lower dose (e.g., 5 mg once daily) and may be adjusted. Plendil 10 mg is typically used when higher strength is required; follow your doctor’s exact instructions.
• Administration: Take the tablets once daily, preferably in the morning, at the same time each day.
• Swallow the tablet whole with a sufficient amount of water. Do not crush, chew, or split the prolonged-release tablet, as this will affect the controlled-release profile.
• Can be taken with or without food, but avoid very large or high-fat meals at the time of dosing unless your doctor advises otherwise.
• Avoid grapefruit or grapefruit juice during treatment, as it may increase felodipine levels and the risk of side effects.
• If you miss a dose: Take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
• Duration of use: Long-term, continuous therapy as directed by your doctor. Do not stop taking Plendil suddenly without medical advice, as this may cause a rise in blood pressure or worsening of angina.

Clinical Benefits:

• Provides effective, 24-hour blood pressure control with once-daily prolonged-release formulation, improving treatment adherence.
• Reduces peripheral vascular resistance by relaxing arterial smooth muscle, leading to lower systolic and diastolic blood pressure.
• Helps decrease myocardial oxygen demand and can improve coronary blood flow, supporting management of chronic stable angina.
• Supports long-term cardiovascular protection by helping to reduce the risk of complications associated with uncontrolled hypertension, such as stroke, heart attack, and kidney damage.
• Vasoselective action primarily on vascular smooth muscle, with minimal direct effect on cardiac conduction at therapeutic doses.
• May be combined with other antihypertensive classes for enhanced blood pressure control when monotherapy is insufficient, as directed by a physician.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to felodipine or any component of the formulation.
• Contraindicated in patients with severe hypotension, cardiogenic shock, or acute myocardial infarction with ongoing instability, unless specifically directed by a cardiologist.
• Use with caution in patients with heart failure, significant aortic stenosis, or other obstructive cardiac outflow conditions; close medical supervision is required.
• Use with caution in patients with liver impairment, as felodipine is extensively metabolized in the liver and dose adjustment may be necessary.
• May cause symptomatic hypotension, especially at treatment initiation or dose increase; caution in elderly patients or those on multiple antihypertensives.
• May cause gingival hyperplasia with long-term use; maintain good oral hygiene and regular dental check-ups.
• Drug interactions: Use caution with other antihypertensives, strong CYP3A4 inhibitors (e.g., certain antifungals, macrolide antibiotics, some antivirals), and inducers (e.g., rifampicin, some anticonvulsants). Avoid grapefruit juice.
• Pregnancy and breastfeeding: Use only if clearly needed and prescribed by a doctor. Consult your healthcare provider before use during pregnancy or lactation.
• May cause dizziness or fatigue; avoid driving or operating machinery until you know how the medicine affects you.
• Consult your doctor before use if you have heart disease, liver disease, very low blood pressure, severe aortic stenosis, or are taking other cardiovascular medications.
• Keep out of reach of children.

Side Effects:

• Common side effects: Headache, flushing, dizziness, palpitations, fatigue, ankle or leg swelling (peripheral edema), and warmth or redness of the skin due to vasodilation.
• Gastrointestinal effects: Nausea, abdominal discomfort, or constipation may occur in some patients.
• Dental effects: Gingival hyperplasia (gum overgrowth) with prolonged use; good oral hygiene and dental follow-up are recommended.
• Less common but serious side effects: Marked hypotension, severe dizziness or fainting, worsening chest pain (angina), or signs of allergic reaction such as rash, itching, swelling of face/lips/tongue, or difficulty breathing.
• Seek immediate medical attention if you experience severe chest pain, signs of heart attack, severe shortness of breath, or symptoms of a serious allergic reaction.
• Inform your doctor if any side effect is persistent, bothersome, or worsening.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature specified on the package insert (exact temperature range not provided; refer to the product carton/leaflet).

Specifications:

• Product type: Prescription antihypertensive medicine
• Active ingredient: Felodipine 10 mg per prolonged-release film-coated tablet
• Form: Prolonged-release film-coated tablet
• Pack size: 30 tablets – typically a 1-month supply for once-daily dosing (depending on prescribed regimen)
• Route of administration: Oral

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.