Special Import - Progynova 2 mg 84 Tablets

Progynova 2 mg 84 Tablets

Description:

Progynova 2 mg 84 tablets is a prescription hormone replacement therapy (HRT) medicine containing estradiol valerate, a synthetic form of the natural female hormone oestrogen. It is used in women with oestrogen deficiency, particularly during or after menopause, to relieve menopausal symptoms such as hot flushes, night sweats, vaginal dryness and mood changes, and to help prevent post‑menopausal bone loss and osteoporosis in selected high‑risk patients. This oral tablet formulation is intended for adult women and must be used under strict medical supervision.

Indications:

• Hormone replacement therapy (HRT) for women with oestrogen deficiency during or after menopause (natural or surgical).
• Relief of moderate to severe vasomotor menopausal symptoms such as hot flushes, night sweats and sleep disturbances.
• Management of genitourinary symptoms of menopause including vaginal dryness, irritation, discomfort during intercourse and urinary urgency/frequency related to oestrogen deficiency.
• Prevention of post‑menopausal osteoporosis in women at increased risk of fractures who are intolerant of, or unsuitable for, other medications approved for osteoporosis prevention (as determined by a physician).
• Hormonal support in certain gynaecological treatment regimens where oestrogen replacement is required, as directed by a specialist.

Active Ingredients / Key Components:

• Estradiol valerate – 2 mg per tablet (oestrogen hormone used for hormone replacement therapy).
• Excipients (inactive ingredients) – include standard tablet fillers, binders and colouring agents (exact composition not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.)).
• Active ingredient concentration details beyond estradiol valerate 2 mg are not available in the provided data.

Dosage & Administration / How to Use:

• Progynova 2 mg is for oral use only and should be taken exactly as prescribed by your doctor.
• The usual regimen for HRT is 1 tablet (2 mg estradiol valerate) once daily, preferably at the same time each day, swallowed with water, with or without food, unless your doctor advises otherwise.
• Your doctor may adjust the dose or treatment schedule based on your symptoms, response to therapy and individual risk factors. Do not change the dose or stop taking the medicine without consulting your doctor.
• In women with an intact uterus, a progestogen is usually added for at least 10–14 days of each cycle to reduce the risk of endometrial hyperplasia and endometrial cancer. Follow your doctor’s instructions regarding any additional progestogen therapy.
• If you forget a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed tablet and continue with your regular schedule. Do not take a double dose to make up for a missed tablet.
• Use the lowest effective dose for the shortest duration consistent with treatment goals and your individual risk profile, as determined by your healthcare provider.
• Regular medical follow‑up (including breast and pelvic examinations, blood pressure checks and review of risk factors) is essential during treatment.

Clinical Benefits:

• Provides effective relief from common menopausal symptoms such as hot flushes, night sweats and sleep disturbances, improving daily comfort and quality of life.
• Helps restore oestrogen levels, supporting the health of urogenital tissues, reducing vaginal dryness and discomfort and improving sexual comfort.
• Contributes to the maintenance of bone mineral density in post‑menopausal women, helping to reduce the risk of osteoporosis and related fractures in appropriately selected patients.
• May help stabilize mood and reduce some emotional and psychological symptoms associated with oestrogen deficiency in menopause, as part of a comprehensive treatment plan.
• Convenient once‑daily oral tablet allows consistent dosing and easier adherence under medical supervision.

Warnings & Contraindications:

• Progynova 2 mg should only be used under the supervision of a qualified healthcare professional experienced in hormone replacement therapy. A thorough assessment of risks and benefits is required before starting treatment.
• Do not use if you are allergic (hypersensitive) to estradiol valerate or any of the tablet’s excipients.
• Contraindicated in women with known, past or suspected breast cancer or oestrogen‑dependent malignant tumours (for example, cancer of the endometrium).
• Contraindicated in women with unexplained vaginal bleeding, untreated endometrial hyperplasia or known/suspected pregnancy.
• Contraindicated in patients with active or recent venous thromboembolism (deep vein thrombosis, pulmonary embolism), known thrombophilic disorders, or a history of arterial thromboembolic disease (such as myocardial infarction or stroke).
• Contraindicated in acute liver disease, a history of liver disease where liver function tests have not returned to normal, or known severe liver impairment.
• Use with caution and only after careful risk assessment if you have risk factors such as obesity, smoking, hypertension, diabetes, high cholesterol, migraine, systemic lupus erythematosus, or a strong family history of breast cancer or thromboembolic disease.
• Stop treatment and seek immediate medical attention if you experience symptoms suggestive of thrombosis or stroke (such as sudden chest pain, shortness of breath, coughing blood, sudden severe headache, vision changes, weakness or numbness in one side of the body).
• Consult your doctor before use if you are taking other medications, including anticoagulants, antihypertensives, thyroid hormones, antiepileptics or herbal products such as St John’s wort, as interactions may occur.
• Not intended for use during pregnancy or breastfeeding.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision. This is a prescription‑only hormone therapy.
• Keep out of reach of children.

Side Effects:

• Common side effects may include breast tenderness or enlargement, nausea, abdominal discomfort, headache, leg cramps, fluid retention (oedema), weight changes, mood changes (including irritability or low mood) and spotting or breakthrough bleeding, especially in the first months of treatment.
• Less common side effects can include changes in libido, skin changes (such as rash or itching), chloasma (patchy skin pigmentation), migraine, dizziness, and changes in blood pressure.
• Serious but less frequent adverse effects include increased risk of venous thromboembolism (blood clots in the veins), stroke, myocardial infarction, gallbladder disease, and certain hormone‑dependent cancers (such as breast or endometrial cancer), particularly with long‑term use and in women with additional risk factors.
• Seek immediate medical attention if you develop chest pain, sudden shortness of breath, coughing blood, severe headache, vision or speech problems, sudden weakness or numbness, severe abdominal pain, jaundice (yellowing of the skin or eyes), or a breast lump.
• If you experience any persistent, bothersome or unusual symptoms while taking Progynova, contact your doctor promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture, ideally below 25–30 °c or as indicated on the package. Keep the tablets in their original blister pack until use to protect from light and humidity. Keep container tightly closed and keep out of reach of children.

Specifications:

• Active ingredient: estradiol valerate 2 mg per tablet.
• Product type: prescription hormone replacement therapy medicine.
• Serving size: 1 tablet (2 mg estradiol valerate), as directed by a physician.
• Count and form: 84 tablets – oral tablets for daily use (often supplied as 3 strips of 28 tablets).
• Intended users: adult women requiring oestrogen replacement during or after menopause, as assessed and prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.