Randil 20 Mg 30 Tablets

Randil 20 Mg 30 Tablets

Description:

Randil 20 mg 30 tablets is a prescription cardiovascular medicine containing nicorandil, an antianginal vasodilator used for the management and prevention of chest pain (angina pectoris) due to coronary artery disease. Nicorandil works as a potassium channel opener and nitric oxide donor, improving blood flow to the heart muscle, reducing the frequency and severity of angina attacks, and enhancing exercise tolerance. It is intended for adult patients under medical supervision as part of a comprehensive heart health and angina management plan.

Indications:

• Prevention and long-term management of chronic stable angina pectoris.
• Reduction in frequency, duration, and intensity of angina attacks (chest pain related to coronary artery disease).
• Improvement of exercise tolerance in patients with ischemic heart disease, by enhancing coronary blood flow.
• Adjunctive therapy in patients with coronary artery disease where additional antianginal control is required, as directed by a cardiologist or physician.

Active Ingredients / Key Components:

• Nicorandil – 20 mg per tablet.
• Excipients: The full list of inactive ingredients (tablet core and coating components such as fillers, binders, disintegrants, colorants, and preservatives) is not available in the provided information. Please refer to the package leaflet for complete excipient details.

Dosage & Administration / How to Use:

• Use only as prescribed by your doctor. Do not self-medicate or adjust the dose without medical advice.
• Typical adult dose for chronic stable angina (for general reference only – your doctor may adjust): often 10–20 mg taken twice daily. The exact regimen must be determined by the treating physician based on clinical condition and response.
• Swallow the tablet whole with a sufficient amount of water. Do not crush or chew unless your doctor or pharmacist specifically advises otherwise.
• Randil 20 mg tablets may be taken with or without food; taking it at the same times each day helps maintain stable blood levels.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Do not stop taking Randil suddenly without consulting your doctor, as abrupt discontinuation may worsen angina symptoms.
• Regular follow-up with your doctor is important to monitor blood pressure, heart status, and response to treatment.

Clinical Benefits:

• Provides effective antianginal control by dilating both coronary arteries and peripheral blood vessels, improving blood supply to the heart muscle.
• Reduces the frequency and severity of angina attacks, helping to relieve chest pain and discomfort associated with coronary artery disease.
• Improves exercise tolerance and physical activity capacity in patients with chronic stable angina.
• Acts as a potassium channel opener and nitric oxide donor, leading to arterial and venous dilatation, reduction in cardiac preload and afterload, and improved myocardial oxygen balance.
• May provide myocardial protection via ischemic preconditioning mechanisms (mitochondrial k+ atp channel opening), which can help reduce ischemic damage, arrhythmias, and infarct size when used as part of physician-directed therapy.

Warnings & Contraindications:

• Use only under medical supervision. Randil (nicorandil) is a prescription medicine for cardiovascular conditions and is not suitable for self-treatment.
• Contraindicated in patients with known hypersensitivity or allergy to nicorandil or any of the excipients.
• Contraindicated in patients with severe hypotension (very low blood pressure), cardiogenic shock, or acute pulmonary edema, unless specifically managed in a controlled hospital setting.
• Do not use concurrently with phosphodiesterase-5 inhibitors (such as sildenafil, tadalafil, vardenafil) due to risk of severe hypotension.
• Use with caution in patients with low blood pressure, volume depletion, severe heart failure, or those on other vasodilators or antihypertensive medications.
• Gastrointestinal, skin, or mucosal ulceration has been reported with nicorandil, especially at higher doses or in patients with pre-existing ulcers. Inform your doctor immediately if you develop persistent mouth ulcers, anal ulcers, skin ulcers, or gastrointestinal bleeding.
• Use with caution in patients with a history of peptic ulcer disease, inflammatory bowel disease, or diverticular disease.
• Consult your doctor before use if you are pregnant, planning pregnancy, or breastfeeding. Nicorandil should be used in pregnancy or lactation only if the potential benefit justifies the potential risk.
• Inform your doctor about all medicines you are taking, including nitrates, antihypertensives, diuretics, other antianginal agents, and over-the-counter products, to avoid interactions and excessive blood pressure lowering.
• May cause dizziness or light-headedness, especially at the start of treatment or when the dose is increased. Avoid driving or operating machinery until you know how the medicine affects you.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision; it is specifically indicated for physician-diagnosed angina and coronary artery disease.
• Keep out of reach of children.

Side Effects:

• Common side effects may include headache (often dose-related), flushing, dizziness, weakness, palpitations, and a feeling of warmth due to vasodilation.
• Gastrointestinal effects such as nausea, vomiting, abdominal discomfort, or diarrhea may occur in some patients.
• Hypotension (low blood pressure), orthostatic hypotension (drop in blood pressure on standing), and fainting can occur, especially in elderly patients or those on multiple blood pressure-lowering medications.
• Ulcerative reactions (oral ulcers, gastrointestinal ulcers, skin or mucosal ulcers, anal ulcers) have been reported with nicorandil; these may be serious and require discontinuation. Seek medical attention if you notice persistent or painful ulcers or any signs of bleeding.
• Less common side effects may include rash, pruritus (itching), increased heart rate, or edema (swelling).
• Seek immediate medical attention if you experience severe chest pain not relieved by usual treatment, signs of severe hypotension (collapse, severe dizziness), difficulty breathing, severe abdominal pain, black or bloody stools, or any signs of allergic reaction such as swelling of the face, lips, tongue, or throat.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Strength: 20 mg nicorandil per tablet.
• Form: Oral tablets.
• Pack size: 30 tablets per pack.
• Intended use: Prescription antianginal medicine for adults as directed by a physician.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.