Sugarlo Plus 50/850 Mg 30 Tablets

Sugarlo Plus 50/850 Mg 30 Tablets

Description:

Sugarlo Plus 50/850 mg 30 Tablets is an oral anti-diabetic prescription medicine combining vildagliptin and metformin hydrochloride. It is used as part of a comprehensive diabetes care plan to help control blood glucose levels in adults with type 2 diabetes mellitus when diet, exercise, and/or metformin alone are not sufficient. This fixed-dose combination works through complementary mechanisms to improve insulin response, reduce hepatic glucose production, and enhance peripheral glucose utilization, supporting long-term blood sugar management and helping reduce the risk of diabetes-related complications.

Indications:

• Management of type 2 diabetes mellitus in adults, particularly when blood glucose is insufficiently controlled with metformin alone or in patients already treated with the combination of vildagliptin and metformin as separate tablets.
• Helps reduce elevated fasting blood glucose and postprandial (after-meal) blood glucose levels.
• Used as an adjunct to diet and exercise to improve glycemic control.
• May be used in combination with other anti-diabetic agents (such as sulfonylureas or insulin) as directed by a physician to achieve target glycemic control.

Active Ingredients / Key Components:

• Vildagliptin – 50 mg per tablet (a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases incretin levels, enhancing insulin secretion and decreasing glucagon secretion in a glucose-dependent manner).
• Metformin hydrochloride – 850 mg per tablet (a biguanide that decreases hepatic glucose production, improves insulin sensitivity, and enhances peripheral glucose uptake and utilization).
• Other excipients: Not specified in available information. Full excipient list is not available and should be checked on the product pack or patient information leaflet.

Dosage & Administration / How to Use:

• Sugarlo Plus 50/850 mg is a prescription medicine; the exact dose and regimen must be determined by your doctor based on your blood glucose levels, current therapy, kidney function, and overall health.
• Typical adult dosing: Often taken as one tablet twice daily with meals (morning and evening), but the dose and frequency may vary according to medical advice. Do not exceed the maximum daily dose prescribed by your physician.
• Always take the tablets with food to reduce gastrointestinal side effects associated with metformin (such as nausea, abdominal discomfort, and diarrhea).
• Swallow the tablet whole with a glass of water. Do not crush, break, or chew the tablet unless your doctor or pharmacist specifically advises otherwise.
• If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not take a double dose to make up for a missed one.
• Continue to follow a controlled diet, exercise plan, and regular blood glucose monitoring as recommended by your healthcare provider while taking this medicine.
• Use in children and adolescents: Safety and efficacy data are limited; use only if specifically prescribed by a specialist.

Clinical Benefits:

• Provides dual mechanism of action for improved glycemic control by combining vildagliptin (DPP-4 inhibitor) with metformin (biguanide).
• Helps lower fasting and postprandial blood glucose levels, supporting better overall HbA1c control in type 2 diabetes.
• Metformin component helps reduce hepatic glucose production and improves insulin sensitivity in muscle and adipose tissue, promoting peripheral glucose utilization.
• Vildagliptin enhances the body’s own incretin system, increasing insulin secretion and reducing glucagon secretion in a glucose-dependent manner, with a low risk of hypoglycemia when used without sulfonylureas or insulin.
• May help improve or stabilize body weight compared to some other anti-diabetic therapies, as metformin is generally weight-neutral or may support modest weight reduction.
• Convenient fixed-dose combination can improve treatment adherence by reducing the number of tablets compared with taking vildagliptin and metformin separately.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to vildagliptin, metformin, or any of the excipients.
• Contraindicated in patients with severe renal impairment or significant reduction in kidney function, and in conditions that may affect kidney function (e.g., severe dehydration, shock, severe infection). Metformin accumulation can lead to lactic acidosis.
• Contraindicated in acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.
• Use with caution in patients with hepatic impairment or a history of liver disease, as vildagliptin has been associated with rare cases of liver dysfunction.
• Stop metformin-containing products temporarily before and after radiological examinations involving iodinated contrast media or major surgery, as advised by your doctor, due to risk of acute kidney injury and lactic acidosis.
• Alcohol intake should be limited or avoided during treatment, as excessive alcohol increases the risk of lactic acidosis with metformin.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. Insulin is usually preferred during pregnancy; this medicine should only be used if clearly needed and prescribed by a specialist.
• Use with caution in elderly patients; kidney function should be assessed regularly before and during treatment.
• Monitor liver function tests periodically as recommended by your doctor during treatment with vildagliptin-containing products.
• May cause hypoglycemia when used in combination with sulfonylureas or insulin; dose adjustments of the concomitant therapy may be required.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision. This is a prescription-only medicine and must be used strictly under the guidance of a healthcare professional.
• Keep out of reach of children.

Side Effects:

• Common side effects (usually mild to moderate): nausea, vomiting, diarrhea, abdominal pain, loss of appetite, indigestion, headache, dizziness, and mild upper respiratory symptoms.
• Metformin-related gastrointestinal effects are more likely at treatment initiation and often improve when taken with food and with gradual dose titration.
• Rare but serious side effect: lactic acidosis (a medical emergency), characterized by symptoms such as rapid breathing, severe weakness, muscle pain, unusual sleepiness, abdominal discomfort, and feeling very unwell. Seek immediate medical attention if these occur.
• Vildagliptin has been associated rarely with liver dysfunction; symptoms may include fatigue, loss of appetite, dark urine, or yellowing of the skin or eyes (jaundice). Contact your doctor immediately if these appear.
• Hypoglycemia (low blood sugar) is uncommon when used alone but may occur more frequently when combined with sulfonylureas or insulin. Symptoms include sweating, tremor, hunger, palpitations, confusion, or dizziness. Treat promptly with fast-acting carbohydrates and seek medical advice if severe or recurrent.
• Allergic reactions such as rash, itching, or swelling may occur. Severe reactions (e.g., difficulty breathing, swelling of face, lips, or tongue) require urgent medical attention.
• If you experience any unexpected, persistent, or severe side effects, stop taking the medicine and consult your doctor or pharmacist immediately.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature specified on the outer packaging (exact storage temperature range is not available here; refer to the product carton or leaflet for precise instructions). Do not use if the blister pack is damaged.

Specifications:

• Product type: Oral anti-diabetic medicine (fixed-dose combination).
• Strength: 50 mg vildagliptin + 850 mg metformin hydrochloride per tablet.
• Form: Film-coated tablets.
• Pack size: 30 tablets per pack.
• Intended users: Adults with type 2 diabetes mellitus, as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.