supranil 25mg 30cap

supranil 25mg 30cap

Description:

Supranil 25mg 30cap is a prescription antidepressant medicine containing clomipramine, a tricyclic antidepressant (TCA) with strong anti-obsessional properties. It is primarily used in the management of depressive disorders and obsessive compulsive disorder (OCD), and may also be used as adjunctive treatment of cataplexy associated with narcolepsy under medical supervision. Supranil works by inhibiting the reuptake of the neurotransmitters noradrenaline and serotonin (5-ht) in the central nervous system, increasing their concentration in the synaptic cleft and helping to improve mood, reduce obsessive thoughts, and stabilize emotional state.

Indications:

• Treatment of depressive disorders, including major depression, with symptoms such as persistent low mood, loss of interest, sleep disturbance, and reduced energy (as prescribed by a psychiatrist or physician).
• Treatment of obsessive compulsive disorder (OCD), helping to reduce intrusive obsessive thoughts and repetitive compulsive behaviors.
• Adjunctive treatment of cataplexy associated with narcolepsy (sudden loss of muscle tone), as part of a comprehensive management plan prescribed by a specialist.
• May be used in other indications only if specifically directed by a healthcare professional, according to approved guidelines.

Active Ingredients / Key Components:

• Clomipramine hydrochloride – 25 mg per capsule (tricyclic antidepressant, tertiary amine).
• Other excipients: Not specified in available data. Full list of inactive ingredients is not available; refer to the printed package insert for complete composition.

Dosage & Administration / How to Use:

• Supranil 25mg 30cap is for oral use only and must be taken exactly as prescribed by your doctor. Do not adjust the dose or stop treatment without medical advice.
• Adults – Depression:
  - Usual initial dose: 10 mg at night (typically using lower-strength tablets/capsules).
  - The dose is then gradually increased, as tolerated, up to about 150 mg per day, given as a single dose at night or in 3–4 divided doses, according to physician instructions.
  - Maintenance dose: usually 30–50 mg daily, adjusted individually based on response and tolerability.
  - Maximum dose: generally should not exceed 250 mg per day.
• Adults – Obsessive Compulsive Disorder (OCD):
  - Initial dose: 25 mg at night.
  - The dose can be gradually increased, as directed by the physician, up to about 150 mg per day, given as a single dose at night or in 3–4 divided doses.
• Cataplexy associated with narcolepsy:
  - Dose and titration are individualized and determined strictly by a specialist; follow the exact regimen provided by your doctor.
• Capsules should be swallowed whole with a sufficient amount of water. Do not crush or chew the capsules.
• Can be taken with or without food; if gastric upset occurs, taking it with food or after meals may help.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Duration of therapy is usually long term (several months or more). Do not stop treatment abruptly; the dose should be tapered gradually under medical supervision to reduce the risk of withdrawal symptoms.

Clinical Benefits:

• Helps relieve symptoms of depression by increasing serotonin and noradrenaline levels in the brain, improving mood, motivation, and overall mental well-being.
• Provides strong anti-obsessional effect, reducing the frequency and intensity of obsessive thoughts and compulsive behaviors in patients with OCD.
• Contributes to better sleep patterns and reduction of anxiety symptoms that often accompany depression and OCD.
• Acts as an adjunctive option in the management of cataplexy associated with narcolepsy, helping to decrease sudden episodes of muscle weakness.

Warnings & Contraindications:

• Use only under medical supervision. Supranil (clomipramine) is a prescription medicine and should not be used without a doctor’s evaluation and follow-up.
• Contraindicated in patients with known hypersensitivity to clomipramine, other tricyclic antidepressants, or any component of the formulation.
• Contraindicated in patients who are currently taking, or have taken within the last 14 days, monoamine oxidase inhibitors (maois) due to risk of serious, potentially fatal interactions.
• Contraindicated in acute recovery phase after myocardial infarction and in certain serious cardiac arrhythmias; caution is required in patients with any cardiovascular disease.
• Use with extreme caution in patients with a history of seizures/epilepsy, glaucoma (especially narrow-angle glaucoma), urinary retention, prostatic hypertrophy, severe liver disease, or thyroid dysfunction.
• May increase the risk of suicidal thoughts and behaviors, particularly in young adults and during the initial weeks of treatment or after dose changes. Close monitoring by caregivers and healthcare professionals is essential.
• May cause drowsiness, dizziness, blurred vision, and impaired concentration. Avoid driving, operating machinery, or performing tasks requiring alertness until you know how the medicine affects you.
• Avoid alcohol while taking clomipramine as it may enhance sedative effects and increase side effects.
• Consult your doctor before use if pregnant or planning pregnancy. Clomipramine should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.
• Consult your doctor before use if breastfeeding; clomipramine may pass into breast milk, and a decision should be made to discontinue nursing or discontinue the drug.
• Inform your doctor about all other medications you are taking, including other antidepressants, antipsychotics, antiarrhythmics, antihypertensives, anticoagulants, and herbal products (e.g. St. John’s wort) due to potential interactions.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision and prescription.
• Keep out of reach of children. Accidental ingestion in children can be dangerous and requires immediate medical attention.

Side Effects:

• Common side effects: dry mouth, constipation, nausea, vomiting, abdominal discomfort, increased appetite or weight changes, sweating, dizziness, drowsiness, fatigue, tremor, blurred vision, difficulty in urination, and mild increase in heart rate.
• Less common but important side effects: confusion (especially in elderly), mood changes, agitation, insomnia, sexual dysfunction (decreased libido, difficulty with ejaculation or orgasm), orthostatic hypotension (drop in blood pressure when standing), and skin rash.
• Serious side effects – seek immediate medical attention: signs of allergic reaction (swelling of face, lips, tongue, or throat, severe rash, difficulty breathing), severe dizziness or fainting, irregular or fast heartbeat, seizures, severe constipation or abdominal pain, yellowing of the skin or eyes (jaundice), unusual bleeding or bruising, or worsening depression or suicidal thoughts.
• If any side effect is severe, persistent, or worrying, contact your doctor or pharmacist promptly. Do not stop the medication suddenly without medical advice.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the container tightly closed and store at or below the temperature recommended on the package insert (typically below 25°c, if stated). Do not use after the expiry date printed on the pack. Keep out of reach and sight of children.

Specifications:

• Product type: Prescription antidepressant medicine (tricyclic antidepressant).
• Active ingredient strength: clomipramine hydrochloride 25 mg per capsule.
• Form: Capsule for oral administration.
• Pack size: 30 capsules per pack.
• Intended users: Adults, and only under specialist guidance in other age groups as per official recommendations.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.