Vendexine Syrup

Vendexine Syrup

Description:

Vendexine Syrup 125 ml is a prescription oral medicine from Eva Pharma that combines an antihistamine (chlorpheniramine) with a corticosteroid (dexamethasone). It is formulated to relieve moderate to severe allergic and inflammatory conditions affecting the respiratory tract and other body systems. By reducing histamine activity and suppressing inflammatory responses, Vendexine Syrup helps control symptoms such as sneezing, itching, runny nose, swelling, and other allergy-related discomforts. It is intended for use under medical supervision only.

Indications:

• Treatment of moderate to severe allergic conditions, as prescribed by a physician
• Relief of symptoms of allergic rhinitis such as sneezing, runny or blocked nose, nasal itching, and watery eyes
• Adjunct treatment in certain inflammatory and allergic conditions of the upper and lower respiratory tract (e.g., allergic bronchitis, allergic sinusitis), as directed by a doctor
• Relief of itching, redness, and swelling associated with allergic reactions (e.g., drug allergy, insect bites), when oral corticosteroid–antihistamine therapy is indicated
• Management of other corticosteroid-responsive allergic and inflammatory conditions where combination therapy with an antihistamine is clinically appropriate

Active Ingredients / Key Components:

• Chlorpheniramine (as chlorpheniramine maleate) – antihistamine (exact concentration in mg per 5 ml is not available in the provided information)
• Dexamethasone – systemic corticosteroid / glucocorticoid (exact concentration in mg per 5 ml is not available in the provided information)
• Other excipients: information about non-active ingredients (flavoring agents, sweeteners, preservatives, etc.) is not available in the provided information.

Dosage & Administration / How to Use:

• Vendexine Syrup must be used exactly as prescribed by your physician. Do not adjust the dose or duration without medical advice.
• Typical dosing is based on age, body weight, and the severity of the condition. The exact dose (ml per dose and number of doses per day) should be determined by the doctor.
• Shake the bottle well before each use to ensure uniform distribution of the active ingredients.
• Measure the dose accurately using a medical measuring spoon or oral syringe; do not use household teaspoons.
• Vendexine Syrup can usually be taken with or without food. If stomach upset occurs, taking it with food or milk may be helpful, as advised by your doctor.
• Duration of therapy should be as short as possible and strictly according to your doctor’s instructions, especially because of the presence of dexamethasone (a corticosteroid).
• Do not abruptly stop treatment if you have been using it for a prolonged period; your doctor may recommend gradual dose reduction to avoid withdrawal or adrenal insufficiency.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Not recommended for self-medication in children; pediatric use must be strictly supervised by a pediatrician.

Clinical Benefits:

• Provides rapid relief from allergy symptoms such as sneezing, runny nose, and itching through antihistamine action.
• Reduces inflammation, swelling, and redness in corticosteroid-responsive conditions due to the potent anti-inflammatory effect of dexamethasone.
• Helps control moderate to severe allergic reactions that may not respond adequately to antihistamines alone.
• Supports easier breathing and improved comfort in allergic and inflammatory respiratory conditions when used as part of a comprehensive treatment plan.

Warnings & Contraindications:

• Use only under medical supervision. Vendexine Syrup contains dexamethasone, a systemic corticosteroid, and chlorpheniramine, a sedating antihistamine.
• Contraindicated in patients with known hypersensitivity or allergy to chlorpheniramine, dexamethasone, other corticosteroids, other antihistamines, or any component of the formulation.
• Contraindicated in systemic fungal infections and in patients receiving live attenuated vaccines (e.g., live viral vaccines) while on immunosuppressive doses of corticosteroids.
• Use with extreme caution in patients with peptic ulcer disease, osteoporosis, uncontrolled hypertension, heart failure, diabetes mellitus, glaucoma, cataracts, psychiatric disorders, or a history of steroid-induced side effects.
• Chlorpheniramine may cause drowsiness; avoid driving, operating machinery, or performing tasks requiring alertness until you know how the medicine affects you.
• Alcohol and other central nervous system depressants may increase drowsiness and sedation; avoid or limit use as advised by your doctor.
• Long-term or high-dose corticosteroid use may suppress the immune system, increase susceptibility to infections, and mask signs of infection.
• Consult your doctor before use if pregnant, nursing, taking other medications (especially other steroids, antihistamines, sedatives, anticoagulants, antidiabetic drugs, or vaccines), or if you have chronic medical conditions such as liver disease, kidney disease, cardiovascular disease, or endocrine disorders.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.
• Do not use beyond the expiry date printed on the package. Do not use if the bottle is damaged or the seal is broken.

Side Effects:

• Common side effects related to chlorpheniramine may include drowsiness, dizziness, dry mouth, blurred vision, constipation, or difficulty concentrating.
• Possible side effects related to dexamethasone (especially with prolonged use or higher doses) may include increased appetite, weight gain, mood changes, insomnia, elevated blood pressure, increased blood sugar, fluid retention, and susceptibility to infections.
• Other potential side effects: stomach upset, nausea, headache, or changes in menstrual cycle.
• Serious side effects (seek immediate medical attention): severe allergic reaction (rash, itching, swelling of face or throat, severe dizziness, difficulty breathing), severe abdominal pain or black/tarry stools, vision changes, severe mood or behavior changes, signs of infection (fever, persistent sore throat), or signs of adrenal suppression (extreme tiredness, weakness, dizziness).
• This is not a complete list of side effects. Inform your doctor or pharmacist about any unusual or persistent symptoms.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not freeze. Store at or below the temperature specified on the package insert (exact temperature range is not available in the provided information). Discard any remaining syrup after the period recommended by the manufacturer once the bottle is opened, if stated on the label.

Specifications:

• Product type: Oral prescription medicine (antihistamine + corticosteroid combination)
• Form: Syrup
• Volume: 125 ml bottle
• Route of administration: Oral
• Active ingredients: chlorpheniramine + dexamethasone (exact concentrations , please check the product leaflet or the manufacturer’s official website)

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.