Vildagluse Plus 50/1000 30 Cap

Vildagluse Plus 50/1000 30 Cap

Description:

Vildagluse Plus 50/1000 30 Cap is an oral anti-diabetic prescription medicine used to improve blood glucose control in adults with type 2 diabetes mellitus. It combines two active ingredients, vildagliptin (a dpp-4 inhibitor) and metformin hydrochloride (a biguanide), in a single tablet to help lower blood sugar levels when diet and exercise alone are not sufficient. This combination works by increasing insulin release in response to meals, reducing glucose production in the liver, and improving the body’s sensitivity to insulin, making it a key option in comprehensive diabetes care and long-term blood sugar management.

Indications:

• Management of type 2 diabetes mellitus in adults, particularly when blood glucose is not adequately controlled by metformin alone, diet, and exercise.
• Helps reduce elevated fasting and postprandial (after-meal) blood glucose levels.
• May be used as part of combination therapy with other anti-diabetic medications as directed by a physician.
• Aims to lower the risk of diabetes-related complications associated with poor glycemic control, such as neuropathy, nephropathy, and cardiovascular events, as part of an overall treatment plan.

Active Ingredients / Key Components:

• Vildagliptin – 50 mg per tablet (dpp-4 inhibitor / insulin secretagogue).
• Metformin hydrochloride – 1000 mg per tablet (biguanide class anti-diabetic).
• Other excipients: Information on inactive ingredients (excipients, coloring agents, preservatives, coating materials) is not available in the provided data. Please refer to the official package insert for the full excipient list.

Dosage & Administration / How to Use:

• Use exactly as prescribed by your physician. Do not change your dose or stop the medication without medical advice.
• Typical adult dose: One tablet (50 mg vildagliptin / 1000 mg metformin) taken once or twice daily, as determined by the treating physician based on blood glucose control and tolerance. The exact regimen must be individualized.
• Administration: Swallow the tablet whole with a glass of water. Do not crush or chew unless your doctor or pharmacist advises otherwise.
• Take with food or shortly after a meal to reduce gastrointestinal side effects associated with metformin (such as nausea, abdominal discomfort, or diarrhea).
• If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed one.
• Regular monitoring of blood glucose, and when indicated HbA1c, renal function, and liver function is recommended during treatment.
• Not recommended for use in children and adolescents unless specifically prescribed by a specialist.

Clinical Benefits:

• Provides dual mechanism of action by combining vildagliptin and metformin to improve overall glycemic control in type 2 diabetes.
• Helps reduce both fasting and postprandial blood glucose levels, supporting more stable daily blood sugar profiles.
• Vildagliptin enhances glucose-dependent insulin secretion and decreases glucagon levels, improving the body’s natural response to meals.
• Metformin decreases hepatic glucose production and improves peripheral insulin sensitivity, contributing to better long-term glycemic control.
• Combination in a single tablet may improve treatment adherence compared to taking separate medications.
• Supports long-term diabetes management as part of a comprehensive plan including diet, exercise, and lifestyle modification.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to vildagliptin, metformin, or any of the tablet’s components.
• Contraindicated in patients with severe renal impairment or end-stage renal disease, and in conditions that may affect kidney function (e.g., severe dehydration, severe infection, shock).
• Contraindicated in acute or chronic metabolic acidosis, including diabetic ketoacidosis and lactic acidosis, with or without coma.
• Use with caution in patients with liver impairment or a history of liver disease; liver function monitoring may be required.
• Risk of lactic acidosis: Metformin can rarely cause lactic acidosis, a serious metabolic complication. Risk is increased in renal impairment, uncontrolled diabetes, prolonged fasting, excessive alcohol intake, hepatic impairment, or conditions associated with hypoxia (e.g., heart failure, recent myocardial infarction, respiratory failure).
• Temporarily discontinue metformin-containing medicines before and after procedures involving iodinated contrast media or major surgery, as advised by your doctor.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. Use during pregnancy or lactation should be based on medical advice and risk–benefit assessment.
• Use with caution in elderly patients; kidney function should be regularly monitored.
• May cause dizziness in some patients; if affected, avoid driving or operating machinery until you know how the medicine affects you.
• Consult your doctor before use if you have heart disease, liver disease, kidney disease, a history of pancreatitis, alcohol abuse, or other serious medical conditions.
• Keep out of reach of children.

Side Effects:

• Common side effects: Nausea, vomiting, diarrhea, abdominal pain, indigestion, loss of appetite, headache, dizziness, and mild upper respiratory tract symptoms.
• Less common side effects: Metallic taste in the mouth, mild peripheral edema, fatigue, or mild skin reactions such as rash or itching.
• Hypoglycemia (low blood sugar) is more likely when this medicine is used in combination with other anti-diabetic drugs such as sulfonylureas or insulin. Symptoms include sweating, tremor, hunger, palpitations, confusion, or dizziness.
• Rare but serious side effects: Lactic acidosis (symptoms may include rapid breathing, muscle pain, stomach pain, severe weakness, feeling cold, dizziness, or slow/irregular heartbeat), severe liver dysfunction, or pancreatitis (severe abdominal pain radiating to the back, nausea, vomiting).
• Seek immediate medical attention if you experience signs of lactic acidosis, severe allergic reaction (swelling of face, lips, tongue, or throat; difficulty breathing; severe rash), severe abdominal pain, yellowing of the skin or eyes, or unexplained fatigue and dark urine.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer carton to protect from light. Do not store above the temperature stated on the package (specific temperature information is not available in the provided data; refer to the official pack). Keep container tightly closed and keep out of reach of children.

Specifications:

• Form: Film-coated tablets (caps indicated in name; oral solid dosage form).
• Strength: 50 mg vildagliptin / 1000 mg metformin hydrochloride per tablet.
• Pack size: 30 tablets per pack.
• Route of administration: Oral.
• Intended for: Adult patients with type 2 diabetes mellitus, as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.