Vildagluse Plus 50/850 30 Cap

Vildagluse Plus 50/850 30 Cap

Description:

Vildagluse Plus 50/850 is an oral anti-diabetic prescription medicine in capsule form that combines vildagliptin (a dpp-4 inhibitor) with metformin hydrochloride (a biguanide). It is formulated to improve blood glucose control in adults with type 2 diabetes mellitus when diet and exercise alone are not sufficient, and when combination therapy with these two agents is considered appropriate. By targeting both insulin secretion and insulin sensitivity, Vildagluse Plus 50/850 helps reduce elevated fasting and post‑meal blood sugar levels and supports long‑term diabetes management as part of a comprehensive treatment plan.

Indications:

• Type 2 diabetes mellitus in adults, particularly in patients insufficiently controlled on metformin alone or already receiving vildagliptin plus metformin as separate tablets.
• Improvement of glycemic control (reducing elevated fasting and postprandial blood glucose levels).
• May be used as part of combination therapy with other anti-diabetic agents as directed by a physician (e.g., insulin, sulfonylureas), when appropriate.

Active Ingredients / Key Components:

• Vildagliptin – 50 mg per capsule (dpp-4 inhibitor; enhances glucose‑dependent insulin secretion).
• Metformin hydrochloride – 850 mg per capsule (biguanide; decreases hepatic glucose production and improves insulin sensitivity).
• Other inactive ingredients/excipients: Not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).

Dosage & Administration / How to Use:

• Use only as prescribed by a physician experienced in the management of diabetes.
• Typical adult dose: often 1 capsule taken twice daily with meals (morning and evening), or as directed by your doctor. Exact dosing regimen must be individualized based on blood glucose levels, previous therapy, and tolerability.
• Swallow the capsule whole with a glass of water; do not crush or chew unless your healthcare provider advises otherwise.
• Take with food to reduce the risk of gastrointestinal side effects associated with metformin (such as nausea, abdominal discomfort, and diarrhea).
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Regular monitoring of blood glucose, and periodically kidney and liver function, is recommended during treatment.
• Do not adjust dose or discontinue the medicine without consulting your healthcare provider.

Clinical Benefits:

• Provides dual mechanism of action by combining vildagliptin and metformin to improve overall glycemic control in type 2 diabetes.
• Helps lower fasting and postprandial (after‑meal) blood glucose levels when used alongside diet and exercise.
• Vildagliptin enhances glucose‑dependent insulin secretion and reduces glucagon levels, supporting more physiologic blood sugar regulation.
• Metformin reduces hepatic glucose production and improves peripheral insulin sensitivity, contributing to better long‑term glycemic control.
• Fixed‑dose combination in capsule form may improve treatment convenience and adherence compared to taking the two components separately.

Warnings & Contraindications:

• For use in adults with type 2 diabetes only; not indicated for type 1 diabetes or for the treatment of diabetic ketoacidosis.
• Contraindicated in patients with severe renal impairment, acute or chronic metabolic acidosis (including diabetic ketoacidosis), or known hypersensitivity to vildagliptin, metformin, or any component of the formulation.
• Use with caution in patients with liver impairment or a history of liver disease; liver function monitoring may be required.
• Risk of lactic acidosis associated with metformin, particularly in patients with significant renal impairment, dehydration, severe infection, heart failure, respiratory failure, or in situations of hypoxia. Symptoms include rapid breathing, muscle pain, abdominal discomfort, and severe fatigue; seek urgent medical attention if suspected.
• Discontinue temporarily before major surgery or procedures involving iodinated contrast media, as advised by your doctor.
• May cause hypoglycemia when used in combination with insulin or sulfonylureas; blood glucose monitoring and possible dose adjustments of concomitant therapy may be needed.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. Your physician will decide if this medicine is appropriate or if insulin or another regimen is preferred.
• Inform your healthcare provider about all other medications you are taking, including diuretics, antihypertensives, steroids, or other anti-diabetic drugs, to avoid interactions.
• Avoid excessive alcohol intake during treatment, as it may increase the risk of lactic acidosis and affect blood sugar control.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects (often related to metformin) may include nausea, vomiting, diarrhea, abdominal discomfort, loss of appetite, and metallic taste. These are often mild and may improve with continued use or dose adjustment.
• Other possible side effects can include headache, dizziness, mild upper respiratory symptoms, or peripheral edema (swelling), particularly related to vildagliptin.
• Hypoglycemia (low blood sugar) is more likely when Vildagluse Plus is used with other glucose‑lowering agents such as insulin or sulfonylureas; symptoms include sweating, shakiness, hunger, palpitations, and confusion.
• Rare but serious side effects include lactic acidosis (a medical emergency) and liver function abnormalities. Seek immediate medical attention if you experience severe weakness, rapid breathing, unusual muscle pain, abdominal pain, dizziness, yellowing of the skin or eyes, or dark urine.
• If you notice any allergic reactions such as rash, itching, swelling of the face, lips, or tongue, or difficulty breathing, stop the medicine and seek urgent medical care.
• Always report any persistent, severe, or unusual side effects to your healthcare provider.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Do not store above the temperature specified on the package insert (information not available here; refer to the product pack).

Specifications:

• Product type: Oral anti-diabetic medicine.
• Strength: 50 mg vildagliptin + 850 mg metformin hydrochloride per capsule.
• Form: Capsules.
• Pack size: 30 capsules per pack.
• Intended use: Adult patients with type 2 diabetes mellitus, as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.