Xolamol Eye Drops

Xolamol Eye Drops

Description:

Xolamol Eye Drops 5 ml is a prescription ophthalmic medicine used to lower raised intraocular pressure in various types of glaucoma and ocular hypertension. It combines two proven antiglaucoma agents, dorzolamide (a topical carbonic anhydrase inhibitor) and timolol (a non-selective beta-adrenergic blocker), to reduce aqueous humor production and effectively decrease intraocular pressure. This dual-action eye drop is intended for adult patients and older adults under the supervision of an eye specialist and is commonly used as monotherapy or adjunctive therapy when a single agent is insufficient to control intraocular pressure.

Indications:

• Reduction of elevated intraocular pressure in patients with open-angle glaucoma.
• Management of ocular hypertension (raised pressure inside the eye without visible optic nerve damage).
• May be used in patients not adequately controlled with a single antiglaucoma agent.
• Helps reduce the risk of progressive optic nerve damage and visual field loss associated with chronically elevated intraocular pressure.

Active Ingredients / Key Components:

• Dorzolamide hydrochloride – concentration not specified in available data (commonly used as a topical carbonic anhydrase inhibitor to reduce aqueous humor secretion).
• Timolol maleate – concentration not specified in available data (a non-selective beta-adrenergic blocker that decreases aqueous humor production).
• Other excipients: Information on preservatives (e.g., benzalkonium chloride) and additional inactive ingredients is not available in the provided data. Please refer to the product leaflet for the full excipient list.

Dosage & Administration / How to Use:

• Use only as prescribed by your ophthalmologist or healthcare provider.
• Typical adult dose (if prescribed as monotherapy or adjunct therapy): usually 1 drop in the affected eye(s) twice daily (morning and evening). Exact dosing regimen should follow your doctor’s instructions and the official product leaflet.
• Wash your hands thoroughly before use.
• Shake the bottle gently if recommended by the leaflet (if applicable).
• Tilt your head back, gently pull down the lower eyelid to form a small pocket, and instill 1 drop into the conjunctival sac without touching the eye or eyelids with the dropper tip.
• Close your eyes gently and apply light pressure with a finger to the inner corner of the eye (near the nose) for 1–2 minutes to reduce systemic absorption.
• If using other ophthalmic medications, leave at least 5–10 minutes between different eye drops. Ointments should be applied last.
• Do not wear soft contact lenses during instillation if the product contains preservatives such as benzalkonium chloride; remove lenses before use and wait at least 15 minutes before reinsertion (check leaflet for confirmation).
• Do not exceed the prescribed dose or frequency. If a dose is missed, apply it as soon as you remember unless it is almost time for the next dose. Do not double the dose.

Clinical Benefits:

• Effectively lowers intraocular pressure by combining two complementary mechanisms of action (carbonic anhydrase inhibition and beta-blockade).
• Helps slow the progression of glaucomatous optic nerve damage and visual field loss when used regularly as prescribed.
• May reduce the need for multiple separate eye drops by providing a fixed-dose combination, improving treatment convenience and adherence.
• Provides sustained intraocular pressure control throughout the day when used twice daily.

Warnings & Contraindications:

• Contraindicated in patients with hypersensitivity to dorzolamide, timolol, sulfonamides, beta-blockers, or any component of the formulation.
• Contraindicated in patients with bronchial asthma, a history of bronchial asthma, or severe chronic obstructive pulmonary disease (copd), due to the risk of bronchospasm from timolol.
• Contraindicated in patients with sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock.
• Use with caution in patients with cardiovascular disease (e.g., coronary artery disease, heart failure, hypotension), peripheral vascular disease, or conduction disturbances; close monitoring is recommended.
• Use with caution in patients with diabetes mellitus, as beta-blockers may mask signs of hypoglycemia.
• Use with caution in patients with thyroid disorders, particularly hyperthyroidism, as beta-blockers may mask signs of thyrotoxicosis.
• Use with caution in patients with a history of severe allergic reactions, as beta-blockers may increase the severity of anaphylactic reactions and reduce response to epinephrine.
• Systemic absorption of timolol may occur; concomitant use with oral beta-blockers, calcium channel blockers, antiarrhythmics, digitalis glycosides, or other antihypertensives may enhance systemic beta-blockade.
• Because dorzolamide is a sulfonamide, systemic-type adverse reactions characteristic of sulfonamides may occur, including severe skin reactions. Discontinue use and seek medical attention if serious reactions develop.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. Use only if the potential benefit justifies the potential risk to the fetus or infant.
• Consult your doctor before use if you have kidney or liver impairment, respiratory disease, cardiac disease, or are taking systemic beta-blockers or other glaucoma medications.
• Not intended for use in children unless specifically prescribed by a pediatric ophthalmologist.
• Do not use if the solution changes color, becomes cloudy, or if the seal is broken or bottle is damaged.
• Do not touch the dropper tip to any surface, including the eye or hands, to avoid contamination and potential eye infection.
• Keep out of reach of children.

Side Effects:

• Common local side effects may include burning or stinging sensation in the eye, blurred vision immediately after instillation, eye redness, itching, tearing, or foreign body sensation.
• Other possible ocular effects: conjunctivitis, eyelid inflammation, dry eye, corneal changes, or allergic reactions.
• Systemic side effects related to timolol (due to absorption) may include bradycardia, low blood pressure, dizziness, fatigue, headache, shortness of breath, or worsening of asthma/copd in susceptible individuals.
• Systemic sulfonamide-type reactions from dorzolamide are rare but may include skin rash, severe skin reactions, fever, or blood disorders; discontinue the product and seek urgent medical advice if such symptoms occur.
• Seek immediate medical attention if you experience severe eye pain, sudden vision changes, swelling of the face or eyelids, difficulty breathing, chest pain, or signs of a severe allergic reaction (such as rash, itching, swelling, severe dizziness, or trouble breathing).

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not freeze. Store at or below the temperature specified on the product carton or leaflet (exact temperature range not available in the provided data). Use within the recommended period after first opening (check the package insert for the in-use shelf life) and discard any remaining solution after that time.

Specifications:

• Product type: Prescription ophthalmic antiglaucoma medicine (eye drops).
• Form: Sterile ophthalmic solution (drops).
• Pack size: 5 ml bottle.
• Route of administration: Topical ocular use only (for the eyes).
• Manufacturer: Jamjoom Pharmaceuticals.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.