Co-Diovan 160/25 Mg 10 Tablets

Co-Diovan 160/25 Mg 10 Tablets

Description:

Co-Diovan 160/25 mg is a prescription antihypertensive medicine combining valsartan (an angiotensin II receptor blocker) and hydrochlorothiazide (a thiazide diuretic) in film-coated tablet form. It is used for the treatment and long-term control of high blood pressure (hypertension) in adults, especially when blood pressure is not adequately controlled by monotherapy. By relaxing blood vessels and increasing the excretion of excess salt and water, Co-Diovan 160/25 mg helps lower blood pressure, reduce cardiovascular risk, and support overall heart and vascular health under medical supervision.

Indications:

• Treatment of essential hypertension (primary high blood pressure) in adults.
• Management of high blood pressure in patients whose blood pressure is not adequately controlled with valsartan or hydrochlorothiazide alone.
• Helps reduce the risk of complications associated with uncontrolled hypertension, such as stroke, heart attack, and kidney damage, as part of a comprehensive cardiovascular risk management plan.

Active Ingredients / Key Components:

• Valsartan – 160 mg per film-coated tablet (angiotensin II receptor blocker, ARB).
• Hydrochlorothiazide – 25 mg per film-coated tablet (thiazide diuretic).
• Other inactive ingredients (excipients) such as tablet core and coating components are present but specific excipient names and concentrations , please check the product leaflet or the manufacturer’s official website.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician experienced in the management of hypertension.
• Typical adult dose: 1 tablet of Co-Diovan 160/25 mg once daily, or as directed by your doctor. The exact dose and duration depend on individual blood pressure response and clinical condition.
• Route of administration: Oral. Swallow the film-coated tablet whole with a glass of water; do not crush or chew.
• May be taken with or without food; take at the same time each day to maintain consistent blood levels.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed tablet.
• Do not stop taking Co-Diovan suddenly without consulting your doctor, as abrupt discontinuation may worsen blood pressure control.
• Regular monitoring of blood pressure, kidney function, and serum electrolytes (especially potassium, sodium, and magnesium) is recommended during treatment.

Clinical Benefits:

• Provides dual antihypertensive action by blocking the effects of angiotensin II (valsartan) and promoting diuresis and natriuresis (hydrochlorothiazide), leading to effective blood pressure reduction.
• Helps lower the risk of cardiovascular events associated with long-term uncontrolled hypertension, such as stroke, myocardial infarction, and heart failure, when used as part of an overall risk-reduction strategy.
• Supports improved vascular function by reducing total peripheral resistance and decreasing plasma volume through controlled excretion of sodium and water.
• Convenient fixed-dose combination in a single daily tablet, which may improve treatment adherence compared with taking separate medicines.

Warnings & Contraindications:

• Contraindicated in patients with hypersensitivity to valsartan, hydrochlorothiazide, other sulfonamide-derived drugs, or any component of the formulation.
• Contraindicated in severe renal impairment, anuria, or severe hepatic impairment, and in patients with cholestasis or biliary cirrhosis where thiazides may not be appropriate.
• Contraindicated during the second and third trimesters of pregnancy due to risk of fetal toxicity and death associated with drugs acting on the renin-angiotensin system.
• Not recommended during breastfeeding unless clearly needed and after medical assessment.
• Use with caution in patients with renal artery stenosis, kidney disease, liver disease, electrolyte imbalance (such as low sodium, low potassium, or low magnesium), gout, diabetes, or a history of severe allergic reactions.
• May cause electrolyte disturbances (e.g., hypokalemia, hyponatremia, hypomagnesemia) and changes in kidney function; regular laboratory monitoring is advised.
• Concomitant use with potassium supplements, potassium-sparing diuretics, or salt substitutes containing potassium may increase the risk of hyperkalemia; use only under strict medical supervision.
• Use cautiously with other antihypertensive agents, diuretics, lithium, non-steroidal anti-inflammatory drugs (nsaids), or medicines that affect the renin-angiotensin-aldosterone system due to potential interactions.
• May cause dizziness or fatigue, especially at the start of treatment or when the dose is increased; caution is advised when driving or operating machinery until you know how the medicine affects you.
• Consult your doctor before use if pregnant, nursing, taking medications, or have medical conditions such as kidney disease, liver disease, diabetes, heart failure, or gout.
• Keep out of reach of children.
• Not intended to diagnose, treat, cure, or prevent any disease outside its approved medical indications.

Side Effects:

• Common side effects may include dizziness, headache, fatigue, low blood pressure (hypotension), increased urination, and mild gastrointestinal discomfort (nausea, abdominal pain).
• Electrolyte disturbances such as low potassium, low sodium, or low magnesium levels may occur, potentially causing muscle weakness, cramps, or irregular heartbeat.
• Possible changes in kidney function, including increased serum creatinine or blood urea nitrogen, particularly in patients with pre-existing kidney disease or those taking other nephrotoxic drugs.
• Less common side effects may include rash, photosensitivity (increased sensitivity to sunlight), gout attacks, or elevated blood glucose or uric acid levels.
• Serious but rare reactions can include severe allergic reactions (angioedema, swelling of face, lips, tongue, or throat), severe hypotension, or significant renal impairment. Seek immediate medical attention if you experience difficulty breathing, severe dizziness, fainting, or swelling of the face or throat.
• Report any unusual or persistent symptoms to your healthcare provider for assessment and possible adjustment of therapy.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer carton to protect from light. Do not store above the temperature specified on the package (typically below 30°c, if stated). Keep container tightly closed and out of reach of children. Do not use after the expiry date printed on the pack.

Specifications:

• Product type: Prescription antihypertensive medicine (fixed-dose combination).
• Form: Film-coated tablet.
• Strength per tablet: Valsartan 160 mg + hydrochlorothiazide 25 mg.
• Pack size: 10 tablets per pack.
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.