Co-Diovan 160/25 Mg 15 Tablets

Co-Diovan 160/25 Mg 15 Tablets

Description:

Co-Diovan 160/25 mg is a prescription antihypertensive medicine combining valsartan (an angiotensin II receptor blocker) and hydrochlorothiazide (a thiazide diuretic) in film‑coated tablet form. It is used for the treatment and long‑term control of high blood pressure (hypertension) in adults, especially when blood pressure is not adequately controlled by a single agent. By relaxing blood vessels and promoting gentle diuresis, Co-Diovan helps reduce elevated blood pressure and lowers the risk of serious cardiovascular events such as stroke and heart attack when used as part of a comprehensive blood pressure management plan.

Indications:

• Treatment of essential hypertension in adults.
• Patients whose blood pressure is not adequately controlled by valsartan or hydrochlorothiazide alone.
• Patients who have been stabilized on the individual components and require a fixed‑dose combination for convenience and adherence.
• Helps reduce the risk associated with persistently high blood pressure, such as cardiovascular and renal complications, when used as directed by a physician.

Active Ingredients / Key Components:

• Valsartan – 160 mg per film‑coated tablet (angiotensin II receptor blocker / ARB).
• Hydrochlorothiazide – 25 mg per film‑coated tablet (thiazide diuretic).
• Other excipients: Full list of inactive ingredients (excipients, colorants, coating agents, preservatives) is not available in the provided information. Please refer to the official package leaflet for the complete composition.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician experienced in the management of hypertension.
• Typical adult dose: 1 tablet of Co-Diovan 160/25 mg once daily, or as directed by your doctor. The exact dose and strength may be adjusted based on blood pressure response and clinical condition.
• Route of administration: Oral. Swallow the tablet whole with a glass of water; do not crush or chew.
• Can be taken with or without food; take at the same time each day to maintain consistent blood levels.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed tablet.
• Do not stop taking Co-Diovan suddenly without consulting your doctor, as abrupt discontinuation may lead to a rise in blood pressure.
• Regular monitoring of blood pressure, kidney function, and electrolytes (especially potassium, sodium, and magnesium) is recommended during treatment.

Clinical Benefits:

• Provides dual antihypertensive action by blocking the effects of angiotensin II (via valsartan) and promoting diuresis and natriuresis (via hydrochlorothiazide), resulting in effective blood pressure reduction.
• Helps lower the risk of cardiovascular complications associated with uncontrolled hypertension, such as stroke, heart attack, and heart failure, when used as part of long‑term blood pressure control.
• Once‑daily fixed‑dose combination improves treatment convenience and may enhance patient adherence compared with taking two separate medicines.
• Hydrochlorothiazide supports additional blood pressure reduction in patients insufficiently controlled on valsartan alone by decreasing plasma volume and peripheral vascular resistance.
• Valsartan selectively blocks angiotensin II type 1 (AT1) receptors, leading to vasodilation and reduced aldosterone‑mediated sodium and water retention, without affecting bradykinin breakdown (lower cough risk compared with ACE inhibitors).

Warnings & Contraindications:

• Contraindicated in patients with hypersensitivity to valsartan, hydrochlorothiazide, other sulfonamide‑derived drugs, or any component of the formulation.
• Contraindicated in severe renal impairment, anuria, or severe hepatic impairment, and in patients with refractory hypokalemia, hypercalcemia, or symptomatic hyperuricemia/gout related to thiazide use.
• Do not use during the second and third trimesters of pregnancy due to risk of fetal toxicity (renal impairment, oligohydramnios, skull hypoplasia, and fetal death). Use in the first trimester is not recommended.
• Not recommended during breastfeeding, as valsartan and hydrochlorothiazide may be excreted in breast milk.
• Use with caution in patients with renal artery stenosis, heart failure, volume depletion, hyponatremia, hypokalemia, or other electrolyte imbalances.
• Monitor serum electrolytes, uric acid, and renal function periodically, especially in elderly patients, those with kidney disease, or those taking other medicines that affect the renin‑angiotensin‑aldosterone system or electrolytes.
• May cause symptomatic hypotension, particularly in patients who are volume‑ or salt‑depleted (e.g., on high‑dose diuretics, low‑salt diet, diarrhea, or vomiting). Initiate therapy cautiously and correct volume depletion if possible before starting.
• Use with caution in patients with diabetes mellitus, gout, hyperuricemia, or a history of photosensitivity reactions to thiazides.
• Drug interactions: Use cautiously with other antihypertensives, potassium‑sparing diuretics, potassium supplements, lithium, NSAIDs, and certain antidiabetic agents. Always inform your doctor about all medicines and supplements you are taking.
• Consult your doctor before use if pregnant, nursing, taking medications, or have medical conditions such as kidney disease, liver disease, heart failure, diabetes, gout, or electrolyte disturbances.
• Not intended for self‑medication; must be used under medical supervision for the treatment of diagnosed hypertension.
• Keep out of reach of children.

Side Effects:

• Common side effects may include dizziness, headache, fatigue, mild hypotension, and gastrointestinal discomfort (nausea, abdominal pain).
• Hydrochlorothiazide‑related effects may include increased urination, electrolyte disturbances (hypokalemia, hyponatremia, hypomagnesemia), increased uric acid (possible gout attacks), and mild increases in blood lipids or blood glucose.
• Valsartan‑related effects may include dizziness, orthostatic hypotension, and rarely kidney function changes or hyperkalemia (elevated potassium), especially in patients with renal impairment or on interacting drugs.
• Serious but less common side effects: severe hypotension, significant electrolyte imbalance, renal impairment, allergic reactions (rash, itching, swelling, difficulty breathing), or photosensitivity reactions. Seek immediate medical attention if any severe or unusual symptoms occur.
• If you experience persistent dizziness, fainting, muscle weakness, irregular heartbeat, severe abdominal pain, or signs of allergic reaction, stop the medicine and contact your doctor or emergency services promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer carton to protect from light. Do not store above the temperature specified on the package (typically below 25–30°c; refer to local pack instructions). Keep container tightly closed and out of reach of children. Do not use after the expiry date printed on the pack.

Specifications:

• Product type: Prescription antihypertensive medicine (fixed‑dose combination of ARB and thiazide diuretic).
• Strength: 160 mg valsartan + 25 mg hydrochlorothiazide per film‑coated tablet.
• Form: Film‑coated tablet for oral use.
• Pack size: 15 tablets per pack.
• Intended users: Adult patients as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.