Coloverin A 30 Tablets

Coloverin A 30 Tablets

Description:

Coloverin A 30 Tablets is a prescription-only oral medicine commonly used in Egypt for the management of irritable bowel syndrome (IBS) and spastic colon. It combines an antispasmodic agent (mebeverine) with a benzodiazepine anxiolytic (chlordiazepoxide) to relieve abdominal cramps, intestinal spasms, and associated anxiety or tension that can worsen gastrointestinal symptoms. Coloverin A helps relax smooth muscles of the gastrointestinal tract and reduces nervous tension, improving overall digestive comfort and quality of life in patients with functional bowel disorders.

Indications:

• Spastic colon and irritable bowel syndrome (IBS).
• Functional bowel disorders associated with intestinal spasms and abdominal pain.
• Abdominal cramps, bloating, and discomfort related to colonic spasm.
• Gastrointestinal symptoms aggravated by anxiety, stress, or emotional tension.
• Adjunctive treatment in conditions where reduction of gut motility and relief of smooth muscle spasm is desired, as assessed by a physician.

Active Ingredients / Key Components:

• Chlordiazepoxide – exact strength per tablet is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.) (benzodiazepine derivative with sedative, anxiolytic, and skeletal muscle relaxant properties).
• Mebeverine hydrochloride – exact strength per tablet is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.) (direct-acting antispasmodic on gastrointestinal smooth muscle).
• Full excipient list (lactose, binders, colorants, etc.) is not available in the provided data. Please refer to the printed package insert for complete composition.

Dosage & Administration / How to Use:

• Use only as prescribed by your physician. Do not exceed the recommended dose.
• Typical adult dosing (for IBS and spastic colon) is usually 1 tablet taken 2–3 times daily, but the exact dose, frequency, and duration must be determined by the treating doctor based on the patient’s condition and response.
• Tablets are taken orally with a sufficient amount of water.
• Can be taken before or after meals as directed by your doctor; some patients may prefer taking it before meals to better control post‑prandial cramps.
• Do not crush or chew the tablets unless your doctor or pharmacist advises otherwise.
• Do not abruptly stop treatment with chlordiazepoxide-containing products after prolonged use without medical supervision, as this may cause withdrawal symptoms. Your doctor may recommend gradual dose reduction.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed dose.
• Not recommended for children unless specifically prescribed by a pediatric specialist.

Clinical Benefits:

• Helps relieve intestinal spasms and colicky abdominal pain associated with irritable bowel syndrome and spastic colon.
• Reduces bloating, discomfort, and altered bowel habits related to functional bowel disorders.
• Provides anxiolytic and calming effect via chlordiazepoxide, which may improve IBS symptoms triggered or worsened by stress and anxiety.
• Improves overall gastrointestinal comfort and may enhance daily functioning and quality of life in patients with chronic spastic colon.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to chlordiazepoxide, mebeverine, other benzodiazepines, or any component of the formulation.
• Chlordiazepoxide is a benzodiazepine; use with extreme caution in patients with a history of drug or alcohol abuse, dependence, or addiction.
• Use with caution in patients with severe hepatic impairment, renal impairment, respiratory insufficiency, sleep apnea, myasthenia gravis, or severe depression.
• May cause drowsiness, dizziness, or impaired concentration. Avoid driving, operating machinery, or performing tasks requiring mental alertness until you know how the medicine affects you.
• Avoid concomitant use with alcohol or other central nervous system depressants (such as opioids, sedative antihistamines, or other anxiolytics) as this may enhance sedative and respiratory depressant effects.
• Long-term use of benzodiazepines may lead to tolerance, physical dependence, and withdrawal symptoms upon abrupt discontinuation. Use the lowest effective dose for the shortest possible duration under medical supervision.
• Pregnancy and breastfeeding: Use only if clearly needed and strictly under physician supervision. Benzodiazepines may affect the fetus or nursing infant.
• Elderly patients are more sensitive to benzodiazepine effects (sedation, falls, confusion); dose adjustment and close monitoring are required.
• Consult your doctor before use if pregnant, nursing, taking medications, or have medical conditions such as liver disease, kidney disease, respiratory disorders, glaucoma, depression, or a history of substance abuse.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include drowsiness, dizziness, fatigue, lightheadedness, and mild sedation due to chlordiazepoxide.
• Gastrointestinal side effects can include nausea, constipation, or, rarely, diarrhea or abdominal discomfort.
• Less common effects may include headache, dry mouth, blurred vision, or changes in appetite.
• Serious side effects (seek immediate medical attention) may include severe allergic reactions (rash, itching, swelling of face or tongue, difficulty breathing), marked confusion, severe drowsiness, respiratory depression, mood or behavior changes, or signs of dependence or withdrawal.
• If you experience any unusual or persistent side effects, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer carton to protect from light. Do not store above the temperature indicated on the package (typically below 30°c, if specified). Keep container tightly closed and keep out of reach of children.

Specifications:

• Form: Tablets for oral use.
• Pack size: 30 tablets per pack.
• Product type: Prescription medicine for irritable bowel syndrome and spastic colon.
• Active ingredients: chlordiazepoxide + mebeverine (exact mg per tablet not specified in available data; refer to package insert).

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.