Diflucan Fluconazole 150 Mg 1 Capsules

Diflucan Fluconazole 150 Mg 1 Capsules

Description:

Diflucan Fluconazole 150 mg is a prescription oral antifungal medicine from Pfizer, supplied as a single capsule for systemic treatment of fungal infections. It contains fluconazole, a triazole antifungal with broad-spectrum activity used to treat mucosal and systemic candidiasis, including vaginal yeast infections, oropharyngeal and esophageal candidiasis, and other susceptible fungal infections. Diflucan works by inhibiting fungal cell membrane synthesis, helping to clear infection and relieve symptoms such as itching, discharge, soreness, and discomfort. It is intended for adult use under medical supervision.

Indications:

• Vaginal candidiasis (vaginal yeast infection) – relief of itching, burning, abnormal discharge, and discomfort.
• Oropharyngeal candidiasis (oral thrush) – white patches in the mouth, soreness, and difficulty swallowing, as prescribed by a doctor.
• Esophageal candidiasis – fungal infection of the esophagus causing pain or difficulty swallowing, as directed by a physician.
• Systemic candidiasis (such as candidemia and disseminated candidiasis) – treatment of susceptible Candida infections in blood or internal organs, under strict medical supervision.
• Cryptococcal infections (e.g., cryptococcal meningitis) – treatment and maintenance therapy in patients as prescribed by a specialist.
• Prevention of fungal infections in patients with weakened immune systems (e.g., chemotherapy, bone marrow transplant, advanced HIV) when recommended by a physician.

Active Ingredients / Key Components:

• Fluconazole – 150 mg per capsule.
• Inactive ingredients (excipients): Full excipient list is not provided in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.). Typical capsule excipients may include fillers, capsule shell components, and stabilizers, but exact components are not specified.

Dosage & Administration / How to Use:

• Use only as prescribed by a physician. Do not self-medicate with antifungal medicines without medical advice.
• For uncomplicated vaginal candidiasis in adults: commonly a single oral dose of 150 mg (1 capsule), taken once, with or without food, as directed by your doctor.
• For other infections (oropharyngeal, esophageal, systemic candidiasis, cryptococcal infections, prophylaxis): dose, frequency, and duration vary widely (e.g., daily dosing over several days or weeks) and must be determined by the treating physician.
• Swallow the capsule whole with a glass of water. Do not crush or chew.
• Can be taken with or without food; taking with food may reduce stomach discomfort in sensitive individuals.
• If you miss a dose (for multi-dose regimens), take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed dose. For the single-dose 150 mg regimen, consult your doctor if you vomit shortly after taking the capsule.
• Duration of treatment depends on the type and severity of infection and your immune status. Always complete the full course prescribed, even if symptoms improve earlier.
• Not recommended for children unless specifically prescribed by a pediatric specialist.

Clinical Benefits:

• Broad-spectrum antifungal action against many Candida species and Cryptococcus, helping to clear fungal infections effectively.
• Systemic oral therapy reaches multiple body sites through the bloodstream, suitable for mucosal and systemic infections.
• Convenient single 150 mg capsule regimen for uncomplicated vaginal candidiasis, improving adherence and patient comfort.
• Helps relieve symptoms of fungal infections such as itching, burning, pain, discharge, and swallowing difficulties.
• Can be used as prophylaxis in high-risk immunocompromised patients to help reduce the risk of invasive fungal infections, when prescribed.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to fluconazole, other azole antifungals, or any component of the formulation.
• Use with extreme caution in patients with liver disease or a history of liver toxicity related to antifungals; serious hepatic reactions, including rare fatalities, have been reported with fluconazole.
• Use with caution in patients with kidney impairment; dose adjustment may be required in multi-dose regimens.
• Fluconazole may prolong the QT interval and has been associated with rare cases of serious cardiac arrhythmias (torsades de pointes). Use cautiously in patients with existing heart rhythm disorders, electrolyte disturbances, or those taking other QT-prolonging drugs.
• Important drug interactions: fluconazole can affect or be affected by many medicines. Based on available information:
  • Cimetidine: may decrease efficacy of fluconazole.
  • Cyclosporine: may increase cyclosporine plasma concentrations; monitoring required.
  • Hydrochlorothiazide: may reduce renal clearance of fluconazole, increasing its levels.
  • Phenytoin: fluconazole may enhance phenytoin levels and effects; monitoring advised.
  • Rifampicin: may decrease fluconazole efficacy; higher doses may be required under medical supervision.
  • Sulfonylureas (e.g., tolbutamide, glyburide, glipizide): risk of enhanced hypoglycemic effect.
  • Warfarin and other coumarin-type anticoagulants: potentiation of anticoagulant effect with increased prothrombin time and bleeding risk.
• Inform your doctor about all medicines you are taking, including over-the-counter drugs, herbal supplements, and vitamins.
• Pregnancy: Use only if clearly needed and prescribed by a doctor after risk–benefit assessment. High or prolonged doses in pregnancy have been associated with fetal harm in some reports.
• Breastfeeding: Fluconazole passes into breast milk. Use only on medical advice, considering dose and duration.
• May cause dizziness or seizures in rare cases; if affected, avoid driving or operating machinery.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.
• Do not exceed the prescribed dose or duration. If symptoms persist or worsen, seek medical advice promptly.

Side Effects:

• Common side effects may include headache, nausea, stomach pain, diarrhea, indigestion, and skin rash.
• Less common side effects can include dizziness, taste changes, vomiting, elevated liver enzymes on blood tests, and fatigue.
• Serious side effects (seek immediate medical attention):
  • Signs of liver problems: persistent nausea, vomiting, loss of appetite, unusual tiredness, dark urine, pale stools, yellowing of skin or eyes (jaundice).
  • Severe skin reactions: widespread rash, blistering, peeling skin, sores in the mouth or eyes (possible Stevens–Johnson syndrome or toxic epidermal necrolysis).
  • Allergic reactions: swelling of face, lips, tongue, or throat, difficulty breathing, severe dizziness, or hives.
  • Irregular heartbeat, palpitations, fainting, or severe dizziness that may indicate a serious heart rhythm problem.
• If you experience any unexpected or severe symptoms, stop taking the medicine and contact your doctor immediately.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Serving size: 1 capsule (150 mg fluconazole).
• Count: 1 capsule per pack.
• Form: Oral capsule.
• Intended use: Prescription antifungal medicine for adults, as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.